Grant Number:	5R01CA239595-02 Interpret this number
Primary Investigator:	Fuemmeler, Bernard
Organization:	Virginia Commonwealth University
Project Title:	Clarifying the Role of Tobacco Retail Outlets on Maternal Smoking During Pregnancy and Child Secondhand Smoke Exposure
Fiscal Year:	2020

Abstract Both smoking and second hand smoke (SHS) exposure are established risk factors for chronic disease and cancer. While the prevalence of smoking has decreased in the population as whole, there are subgroups that are particularly vulnerable to smoke exposure, such as pregnant women and children, and it is recommended to eliminate exposure almost entirely among these subgroups. Many states are active in either planning or proposing new regulations limiting tobacco retail outlet (TRO) density as a means of reducing smoking. Presumably, reducing TRO density should lead to lower levels of adult smoking, which should also reduce maternal smoking during pregnancy and SHS exposure in children. There is scant evidence that TRO density is related to smoking behaviors, and there is no evidence showing that reducing TRO density will extend to vulnerable subgroups and those passively exposed, like pregnant women and children. The purpose of proposed study is to examine the extent to which TRO density is related to biomarkers of smoke exposure (cotinine) in 1000 women during their pregnancy and in 400 children aged 4-10 born of these mothers. In addition, the study will determine the degree to which cotinine levels and TRO density relate to health care utilization and costs during pregnancy and early childhood. To accomplish this study, the team will integrate data on biomarkers of smoke exposure and health-care utilization data from a longitudinal pre-birth cohort with publically available data sources on TROs and census data (American Community Survey). By better understanding the link that TROs have with smoke exposure and the related health-care costs associated with such exposure, we will be better positioned to make data-driven policies that aim to modify the TRO landscape. Successful completion of this project will provide evidence supporting continued efforts to expand policies reducing TRO density and retain them where they are being enacted.




Modeling the Effects of Policies that Restrict Tobacco Retail Outlets on Prenatal Smoke Exposure and Perinatal Health Care Utilization.
Authors: Boyle J. , Barsell D.J. , Zhang J.J. , Oliver J.A. , McClernon F.J. , Dahman B. , Hoyo C. , Fuemmeler B.F. , Wheeler D.C. .
Source: Prevention Science : The Official Journal Of The Society For Prevention Research, 2024-09-04 00:00:00.0; , .
EPub date: 2024-09-04 00:00:00.0.
PMID: 39230657
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Tobacco exposures are associated with health care utilization (HCU) and health care costs in pregnant persons and their newborn babies.
Authors: Fuemmeler B.F. , Dahman B. , Glasgow T.E. , Barsell D.J. , Oliver J.A. , Zhang J. , Hoyo C. , Murphy S.K. , McClernon F.J. , Wheeler D.C. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2024-05-31 00:00:00.0; , .
EPub date: 2024-05-31 00:00:00.0.
PMID: 38818778
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Neighborhood deprivation, racial segregation and associations with cancer risk and outcomes across the cancer-control continuum.
Authors: Fuemmeler B.F. , Shen J. , Zhao H. , Winn R. .
Source: Molecular Psychiatry, 2023-03-03 00:00:00.0; , .
EPub date: 2023-03-03 00:00:00.0.
PMID: 36869227
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Tobacco Retail Outlets, Neighborhood Deprivation and the Risk of Prenatal Smoke Exposure.
Authors: Wheeler D.C. , Boyle J. , Jeremy Barsell D. , Maguire R.L. , Zhang J.J. , Oliver J.A. , Jones S. , Dahman B. , Murphy S.K. , Hoyo C. , et al. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2022-11-12 00:00:00.0; 24(12), p. 2003-2010.
PMID: 35793204
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Spatially Varying Associations of Neighborhood Disadvantage with Alcohol and Tobacco Retail Outlet Rates.
Authors: Wheeler D.C. , Boyle J. , Barsell D.J. , Glasgow T. , McClernon F.J. , Oliver J.A. , Fuemmeler B.F. .
Source: International Journal Of Environmental Research And Public Health, 2022-04-26 00:00:00.0; 19(9), .
EPub date: 2022-04-26 00:00:00.0.
PMID: 35564641
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Neighborhood Deprivation is Associated with Increased Risk of Prenatal Smoke Exposure.
Authors: Wheeler D.C. , Boyle J. , Barsell D.J. , Maguire R.L. , Dahman B. , Murphy S.K. , Hoyo C. , Zhang J. , Oliver J.A. , McClernon J. , et al. .
Source: Prevention Science : The Official Journal Of The Society For Prevention Research, 2022-02-18 00:00:00.0; , .
EPub date: 2022-02-18 00:00:00.0.
PMID: 35179695
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Associations of Alcohol and Tobacco Retail Outlet Rates with Neighborhood Disadvantage.
Authors: Wheeler D.C. , Boyle J. , Barsell D.J. , Glasgow T. , McClernon F.J. , Oliver J.A. , Fuemmeler B.F. .
Source: International Journal Of Environmental Research And Public Health, 2022-01-20 00:00:00.0; 19(3), .
EPub date: 2022-01-20 00:00:00.0.
PMID: 35162162
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DNA Methylation in Babies Born to Nonsmoking Mothers Exposed to Secondhand Smoke during Pregnancy: An Epigenome-Wide Association Study.
Authors: Fuemmeler B.F. , Dozmorov M.G. , Do E.K. , Zhang J.J. , Grenier C. , Huang Z. , Maguire R.L. , Kollins S.H. , Hoyo C. , Murphy S.K. .
Source: Environmental Health Perspectives, 2021 May; 129(5), p. 57010.
EPub date: 2021-05-19 00:00:00.0.
PMID: 34009014
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Evaluation of neighborhood deprivation and store characteristics in relation to tobacco retail outlet sales violations.
Authors: Wheeler D.C. , Do E.K. , Hayes R.B. , Hughes C. , Fuemmeler B.F. .
Source: Plos One, 2021; 16(7), p. e0254443.
EPub date: 2021-07-16 00:00:00.0.
PMID: 34270555
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