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Grant Details

Grant Number: 5R03CA230965-02 Interpret this number
Primary Investigator: Cadmusbertram, Lisa
Organization: University Of Wisconsin-Madison
Project Title: Feasibility Trial of Home-Based Strength Training in Endometrial Cancer Survivors
Fiscal Year: 2020


PROJECT SUMMARY Endometrial cancer survivors are a growing population with high prevalence of inactivity and obesity. Despite the benefits of strength training and the risk of functional limitations for obese individuals, interventions for this population have focused mainly on weight loss and aerobic physical activity. A small number of studies have tested resistance training, but only as part of a larger multi-modal approach; thus the specific benefits of resistance training have not been identified. Due to low long-term success rates of weight loss interventions, focusing on building strength and confidence through resistance training may be a promising approach to engaging endometrial cancer survivors in the process of health lifestyle change. The proposed pilot trial will determine the feasibility and safety of our home-based strength training intervention, which consists of an in- person instructional session followed by video coaching. All equipment is provided and all exercises can be done within the home. This home-based approach is important for preserving our reach to rural cancer survivors. Main outcomes will include adherence to the exercise sessions and the video calls, as well as participant feedback about the intervention. We will also measure anthropometrics, body composition, functional fitness, biomarkers, quality of life, and self-efficacy. However, the core purpose of a pilot study is to establish feasibility rather than to test hypotheses, therefore our specific aims focus specifically on the feasibility of both the intervention and the measures and will provide the data needed to refine our protocols to support a fully-powered trial.


Feasibility and acceptability of home-based strength training in endometrial cancer survivors.
Authors: Gorzelitz J. , Costanzo E. , Gangnon R. , Koltyn K. , Dietz A.T. , Spencer R.J. , Rash J. , Cadmus-Bertram L. .
Source: Journal of cancer survivorship : research and practice, 2023 Feb; 17(1), p. 120-129.
EPub date: 2021-03-06.
PMID: 33675013
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Improvements in strength and agility measures of functional fitness following a telehealth-delivered home-based exercise intervention in endometrial cancer survivors.
Authors: Gorzelitz J.S. , Stoller S. , Costanzo E. , Gangnon R. , Koltyn K. , Dietz A.T. , Spencer R.J. , Rash J. , Cadmus-Bertram L. .
Source: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022 Jan; 30(1), p. 447-455.
EPub date: 2021-07-25.
PMID: 34304292
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