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Grant Details

Grant Number: 5R01CA204356-05 Interpret this number
Primary Investigator: Pechmann, Cornelia
Organization: University Of California-Irvine
Project Title: Social Media Technology for Treating Tobacco Addiction
Fiscal Year: 2020


 DESCRIPTION (provided by applicant): Social Media Technology for Treating Tobacco Addiction. The internet was built for communication. This research project, with its cutting-edge social network approaches and analyses, will examine the potential of the internet, and more specifically social media, to engage health communications for quitting smoking and preventing relapse for addiction treatment and cancer prevention. Further, the design tests the personalized benefits and treatment processes of a women-centered internet cessation intervention. With initial funding from an NIH R34 innovation award, we developed and evaluated a novel online social media intervention for tobacco cessation called Tweet2Quit. Tweet2Quit is a 100-day online intervention that uses a novel, low cost, automated approach to encourage and direct peer-to-peer social support for quitting smoking. Private Twitter groups of 24 smokers are set up, and engagement is encouraged and directed by daily auto feedback and daily auto messages that suggest discussion topics consistent with US treatment guidelines for tobacco use cessation. In a randomized controlled trial (N=160), all participants received advice to quit, referral to the NCI website, and 8 weeks of nicotine patch ("usual care"); and half were then randomized to a Tweet2Quit peer support group to test the net benefit of the social media intervention. At 60-days follow- up, Tweet2Quit participants reported 40% sustained abstinence compared to 20% for controls (p=.017), and engagement in the intervention was related to abstinence (p<.001). Consistent with the tobacco treatment literature, in both study conditions, men were more likely to quit smoking than women, and the gender effect in Tweet2Quit was moderate (d=.55). Notably, women in Tweet2Quit tweeted as much as the men, though the content differed thematically. The proposed randomized controlled evaluation (N=960) of the Tweet2Quit intervention will biochemically verify abstinence out to 6-months follow-up and will test the personalized benefit for women of a women-only versus co-ed Tweet2Quit group. In a 3-arm design, we will compare: 1) usual care, 2) Tweet2Quit-coed, and 3) Tweet2Quit-women only. Each 24-person Tweet2Quit group will include 12 buddy pairs based on similarity in demographics and abstinence goals. Also automated pattern detection will identify dips in tweeting and trigger automated alerts and engagement strategies. Our primary aims test hypothesis 1: Relative to usual care (n=240), Tweet2Quit-coed groups (n=480) will achieve significantly greater bioconfirmed sustained abstinence out to 6-months follow-up, and hypothesis 2: Women in Tweet2Quit will achieve significantly greater bioconfirmed 6-months abstinence in woman-only groups (n=240) vs. coed groups (n=240 women). Our secondary aims are to test the same hypotheses based on 3-month (end of treatment) sustained abstinence and 7-day point prevalence at 1, 3, and 6 months. Exploratory aims will study the Tweet2Quit groups' social network structures with a focus on the identification of buddy pairs and social brokers and test if these relationships are stronger for women in women-only groups versus women in coed groups of Tweet2Quit.


Understanding Hesitation to Use Nicotine Replacement Therapy: A Content Analysis of Posts in Online Tobacco-Cessation Support Groups.
Authors: Phillips C. , Pechmann C. , Calder D. , Prochaska J.J. .
Source: American journal of health promotion : AJHP, 2023 Jan; 37(1), p. 30-38.
EPub date: 2022-07-11.
PMID: 35817548
Related Citations

Buddies as In-Group Influencers in Online Support Groups: A Social Network Analysis of Processes and Outcomes.
Authors: Esmaeeli A. , Pechmann C.C. , Prochaska J.J. .
Source: Journal of interactive marketing : a quarterly publication from the Direct Marketing Educational Foundation, Inc, 2022 May; 57(2), p. 198-211.
EPub date: 2022-04-26.
PMID: 35656556
Related Citations

Application of Automated Text Analysis to Examine Emotions Expressed in Online Support Groups for Quitting Smoking.
Authors: Vogel E.A. , Pechmann C.C. .
Source: Journal of the Association for Consumer Research, 2021 Jul; 6(3), p. 315-323.
EPub date: 2021-05-24.
PMID: 36275173
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Facebook Recruitment Using Zip Codes to Improve Diversity in Health Research: Longitudinal Observational Study.
Authors: Pechmann C. , Phillips C. , Calder D. , Prochaska J.J. .
Source: Journal of medical Internet research, 2020-06-05; 22(6), p. e17554.
EPub date: 2020-06-05.
PMID: 32501274
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The Use of Web-Based Support Groups Versus Usual Quit-Smoking Care for Men and Women Aged 21-59 Years: Protocol for a Randomized Controlled Trial.
Authors: Pechmann C.A. , Calder D. , Phillips C. , Delucchi K. , Prochaska J.J. .
Source: JMIR research protocols, 2020-01-14; 9(1), p. e16417.
EPub date: 2020-01-14.
PMID: 31934869
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Disparities in knowledge and use of tobacco treatment among smokers in California following healthcare reform.
Authors: Young-Wolff K.C. , Adams S.R. , Tan A.S.L. , Adams A.S. , Klebaner D. , Campbell C.I. , Satre D.D. , Salloum R.G. , Carter-Harris L. , Prochaska J.J. .
Source: Preventive medicine reports, 2019 Jun; 14, p. 100847.
EPub date: 2019-03-15.
PMID: 31024786
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The flip side of Natural American Spirit: corporate social responsibility advertising.
Authors: Epperson A.E. , Prochaska J.J. , Henriksen L. .
Source: Tobacco control, 2018 May; 27(3), p. 355-356.
EPub date: 2017-02-25.
PMID: 28237942
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Documentation of e-cigarette use and associations with smoking from 2012 to 2015 in an integrated healthcare delivery system.
Authors: Young-Wolff K.C. , Klebaner D. , Folck B. , Tan A.S.L. , Fogelberg R. , Sarovar V. , Prochaska J.J. .
Source: Preventive medicine, 2018 Apr; 109, p. 113-118.
EPub date: 2018-01-31.
PMID: 29360481
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Tobacco Cessation in Oncology Care.
Authors: Kaiser E.G. , Prochaska J.J. , Kendra M.S. .
Source: Oncology, 2018; 95(3), p. 129-137.
EPub date: 2018-06-19.
PMID: 29920482
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Do you vape? Leveraging electronic health records to assess clinician documentation of electronic nicotine delivery system use among adolescents and adults.
Authors: Young-Wolff K.C. , Klebaner D. , Folck B. , Carter-Harris L. , Salloum R.G. , Prochaska J.J. , Fogelberg R. , Tan A.S.L. .
Source: Preventive medicine, 2017 Dec; 105, p. 32-36.
EPub date: 2017-08-16.
PMID: 28823688
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Innovative approaches to support smoking cessation for individuals with mental illness and co-occurring substance use disorders.
Authors: Das S. , Prochaska J.J. .
Source: Expert review of respiratory medicine, 2017 Oct; 11(10), p. 841-850.
EPub date: 2017-08-09.
PMID: 28756728
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Natural American Spirit Brand Marketing Casts Health Halo Around Smoking.
Authors: Epperson A.E. , Henriksen L. , Prochaska J.J. .
Source: American journal of public health, 2017 May; 107(5), p. 668-670.
PMID: 28398789
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Social Media and Mobile Technology for Cancer Prevention and Treatment.
Authors: Prochaska J.J. , Coughlin S.S. , Lyons E.J. .
Source: American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2017; 37, p. 128-137.
PMID: 28561647
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