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Grant Details

Grant Number: 5R01CA207689-04 Interpret this number
Primary Investigator: Raup-Krieger, Janice
Organization: University Of Florida
Project Title: A Patient-Centered Intervention Using Virtual Technology to Reduce Colorectal Cancer Disparities in Primary Care
Fiscal Year: 2020
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Abstract

PROJECT ABSTRACT Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. Unfortunately, there are significant CRC screening disparities that result in higher rates of CRC-related morbidity and mortality for minority and rural patient populations, particularly in the southern United States. The development of interventions that capitalize on advances in communication, informatics, and computer science have great promise for resolving theoretical and practical problems associated with CRC screening decision-making. The purpose of this proposal is to test the efficacy of a patient-centered, tailored message intervention delivered via virtual technology for increasing CRC screening within guidelines among racial/ethnic minority and rural patients. We hypothesize that exposure to a minimally tailored CRC screening intervention delivered via VHT will lead to improved cognitive processing of the intervention and increased adherence with initial and repeated annual FIT screening completion as compared to a fully tailored, text-only intervention. This hypothesis will be tested through two specific aims. In Specific Aim 1, we will conduct focus groups and think-aloud interviews stratified by geography, gender, and racial/ethnic background to expand and pilot test an intervention that uses a virtual human as a delivery mechanism for CRC screening information. In Specific Aim 2, patients (N = 3,000) will be recruited via primary care clinics and a secure, clinical data warehouse to complete a patient- randomized test of the efficacy of the intervention for promoting initial and repeat FIT testing. Dependent measures will be assessed via patient self-report and chart review. The proposed study will reduce health disparities and associated morbidity and mortality due to CRC via increasing screening among racial/ethnic minority and rural populations.

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Publications

A Pilot Study Determining Comprehension and the Acceptability of a Cancer Research Study Website for Cancer Patients and Caregivers.
Authors: Flood-Grady E. , Neil J.M. , Paige S.R. , Lee D. , Damiani R.E. , Hough D. , Savitsky Z. , George T.J. , Krieger J.L. .
Source: Journal of cancer education : the official journal of the American Association for Cancer Education, 2020 Jun; 35(3), p. 589-598.
PMID: 30847837
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Understanding Perceptions and Attitudes in Breast Cancer Discussions on Twitter.
Authors: Modave F. , Zhao Y. , Krieger J. , He Z. , Guo Y. , Huo J. , Prosperi M. , Bian J. .
Source: Studies in health technology and informatics, 2019-08-21; 264, p. 1293-1297.
PMID: 31438134
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The Influence of Patient Identification and Narrative Transportation on Intentions to Participate in Cancer Research.
Authors: Neil J.M. , Gough A. , Kee F. , George T.J. , Pufahl J. , Krieger J.L. .
Source: Journal of cancer education : the official journal of the American Association for Cancer Education, 2019 Aug; 34(4), p. 725-734.
PMID: 29721780
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Does an interactive trust-enhanced electronic consent improve patient experiences when asked to share their health records for research? A randomized trial.
Authors: Harle C.A. , Golembiewski E.H. , Rahmanian K.P. , Brumback B. , Krieger J.L. , Goodman K.W. , Mainous A.G. , Moseley R.E. .
Source: Journal of the American Medical Informatics Association : JAMIA, 2019-07-01; 26(7), p. 620-629.
PMID: 30938751
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Trends of Parent-Adolescent Drug Talk Styles in Early Adolescence.
Authors: Shin Y. , Pettigrew J. , Miller-Day M. , Hecht M.L. , Krieger J.L. .
Source: Health communication, 2019 07; 34(8), p. 801-810.
EPub date: 2018-02-20.
PMID: 29461099
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Creating an mHealth App for Colorectal Cancer Screening: User-Centered Design Approach.
Authors: Griffin L. , Lee D. , Jaisle A. , Carek P. , George T. , Laber E. , Lok B. , Modave F. , Paskett E. , Krieger J. .
Source: JMIR human factors, 2019-05-08; 6(2), p. e12700.
EPub date: 2019-05-08.
PMID: 31066688
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Recruitment in online research for COPD: leveraging social media and research registries.
Authors: Paige S.R. , Krieger J.L. .
Source: ERJ open research, 2019 Apr; 5(2), .
EPub date: 2019-04-08.
PMID: 30972351
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Measuring health information seeking challenges in chronic disease: A psychometric analysis of a brief scale.
Authors: Paige S.R. , Flood-Grady E. , Krieger J.L. , Stellefson M. , Miller M.D. .
Source: Chronic illness, 2019-03-19; , p. 1742395319836476.
EPub date: 2019-03-19.
PMID: 30889966
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Computer-Mediated Experiences of Patients with Chronic Obstructive Pulmonary Disease.
Authors: Paige S.R. , Stellefson M. , Krieger J.L. , Alber J.M. .
Source: American journal of health education, 2019; 50(2), p. 127-134.
EPub date: 2019-02-26.
PMID: 31641399
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