Grant Number:	6P20CA210284-03 Interpret this number
Primary Investigator:	Castle, Philip
Organization:	Albert Einstein College Of Medicine
Project Title:	Building Research Capacity to Address the Challenge of Non Communicable Diseases and Injuries in Rwanda the Gukorana Research Center
Fiscal Year:	2018

PROJECT SUMMARY/ABSTRACT The primary goal of this proposal is to plan for the development of and launch a sustainable Regional Center of Research Excellence (RCRE) for non-communicable diseases and injuries (NCDIs) in Rwanda. To accomplish this goal, we will establish a bi-lateral, multi-institutional, US-Rwanda collaboration to 1) conduct a rigorous landscape analysis of local infrastructure and human capacities and 2) initiate activities to address gaps in capacity for conducting NCDI research and establishing a RCRE in Rwanda. The initial focus will be on two core areas, cancer and injury, and we will conduct training and education to perform high-quality research in these core areas, and developing the electronic data infrastructure and administration needed to establish/improve disease registration for research purposes. This application leverages long- standing, pre-existing partnerships between Albert Einstein College of Medicine (AECOM), University of Rwanda (UR), Rwanda Military Hospital (RMH), Harvard University Medical School (HMS), Partners in Health (PIH), Virginia Commonwealth University (VCU), King Faisal Hospital, and the Rwanda Biomedical Center (RBC) of the Rwanda Ministry of Health (MOH). The plans for and the subsequent establishment of a RCRE in NCDI will improve the efficiency and effectiveness of research supported by each of these individual institutions by uniting efforts and fostering collaboration within the RCRE and other Rwandan stakeholders. The proposed name of the center is “GUKORANYA” (Global University Consortium for Research in Non- communicable diseases and InjurY) Research Center (GRC). In Kinyarwanda, the national language of Rwanda, the word `gukoranya' means `to gather together'. After building the necessary research capacities and infrastructure, this center will assess the burden of cancer and injury in Rwanda and develop feasible and effective research strategies to inform the public policy and clinical practices for the prevention and treatment of these conditions.




Cancer risk among people living with Human Immuodeficiency Virus (HIV) in Rwanda from 2007 to 2018.
Authors: Dusingize J.C. , Murenzi G. , Muhoza B. , Businge L. , Remera E. , Uwinkindi F. , Hagenimana M. , Rwibasira G. , Nsanzimana S. , Castle P.E. , et al. .
Source: International journal of cancer, 2024-08-11; , .
EPub date: 2024-08-11.
PMID: 39128948
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Building Trauma and EMS Systems Capacity in Rwanda: Lessons and Recommendations.
Authors: Jayaraman S. , Ntirenganya F. , Nkeshimana M. , Rosenberg A. , Dushime T. , Kabagema I. , Uwitonze J.M. , Uwitonize E. , Nyinawankusi J.D. , Riviello R. , et al. .
Source: Annals of global health, 2021; 87(1), p. 104.
EPub date: 2021-10-26.
PMID: 34754760
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Estimating global injuries morbidity and mortality: methods and data used in the Global Burden of Disease 2017 study.
Authors: James S.L. , Castle C.D. , Dingels Z.V. , Fox J.T. , Hamilton E.B. , Liu Z. , Roberts N.L.S. , Sylte D.O. , Bertolacci G.J. , Cunningham M. , et al. .
Source: Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention, 2020 Oct; 26(Supp 1), p. i125-i153.
EPub date: 2020-08-24.
PMID: 32839249
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The Initial Prehospital Management of Traumatic Brain Injuries in Kigali, Rwanda.
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Source: Prehospital and disaster medicine, 2020 Oct; 35(5), p. 533-537.
EPub date: 2020-06-30.
PMID: 32600486
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Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.
Authors: James S.L. , Castle C.D. , Dingels Z.V. , Fox J.T. , Hamilton E.B. , Liu Z. , S Roberts N.L. , Sylte D.O. , Henry N.J. , LeGrand K.E. , et al. .
Source: Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention, 2020 Oct; 26(Supp 1), p. i96-i114.
EPub date: 2020-04-24.
PMID: 32332142
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Authors: Rosenberg A. , Ntirenganya F. , Bagahirwa I. , Mbanjumucyo G. , Rutayisire L. , Muneza S. , Nzeyimana I. , Benimana E. , Nahayo E. , Bhengu B. , et al. .
Source: Journal of global health, 2020 Jun; 10(1), p. 010201.
PMID: 32257131
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Detecting direct oral anticoagulants in trauma patients using liquid chromatography-mass spectrometry: A novel approach to medication reconciliation.
Authors: Jayaraman S. , DeAntonio J.H. , Leichtle S.W. , Han J. , Liebrecht L. , Contaifer D. , Young C. , Chou C. , Staschen J. , Doan D. , et al. .
Source: The journal of trauma and acute care surgery, 2020 Apr; 88(4), p. 508-514.
PMID: 31688825
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Source: The Journal of surgical research, 2020 Feb; 246, p. 482-489.
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Pain in the Prehospital Setting in Rwanda: Results of a Mixed-Methods Quality Improvement Project.
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The epidemiology and prehospital care of motorcycle crashes in a sub-Saharan African urban center.
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Medications and patient safety in the trauma setting: a systematic review.
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