Grant Number:	5R21CA219028-02 Interpret this number
Primary Investigator:	Phillips, Siobhan
Organization:	Northwestern University At Chicago
Project Title:	Incorporating Biomarkers of Prognosis and Cardiovascular Disease Risk in the Fit2thrive Physical Activity Promotion Intervention for Breast Cancer Survivors
Fiscal Year:	2019

PROJECT SUMMARY/ABSTRACT Higher physical activity (PA) is associated with reduced risk of breast cancer (BC) recurrence and progression and increased survival. Increased PA is also associated with reductions in cardiovascular disease (CVD) mortality, the leading cause of non-cancer mortality among BC survivors (BCS). PA may prevent BC progression and CVD via its effects on inflammation and also decrease CVD risk via effects on cardiometabolic biomarkers. However, the exact biologic mechanisms are poorly understood as few PA interventions include biomarkers of BC progression or CVD risk. Additionally, most PA interventions are costly, intense, on-site multicomponent interventions that provide little insight into what components (i.e. phone calls, Fitbits, etc.) are, or are not, effective, and traditional venous blood sample collection is often costly and requires lab visits limiting the potential public health impact of this research. In order to increase




Effects of a Physical Activity mHealth Intervention (Fit2Thrive) on WCRF/AICR Cancer Prevention Score among Breast Cancer Survivors: A Secondary Data Analysis.
Authors: Reading J.M. , Solk P. , Starikovsky J. , Song J. , Hasanaj K. , Wang S. , Siddique J. , Wolter M. , Frey J. , Courneya K.S. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2025-06-09 00:00:00.0; , .
EPub date: 2025-06-09 00:00:00.0.
PMID: 40488447
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Feasibility and acceptability of the Fit2Thrive mHealth physical activity promotion intervention components in breast cancer survivors.
Authors: Solk P. , Song J. , Reading J. , Starikovsky J. , Cullather E. , Wang S. , Hasanaj K. , Morelli W.A. , Spring B. , Cella D. , et al. .
Source: Translational Behavioral Medicine, 2025-01-16 00:00:00.0; 15(1), .
PMID: 40795071
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Acceptability of the Fit2ThriveMB mHealth physical activity promotion intervention in women with metastatic breast cancer.
Authors: Starikovsky J. , Solk P. , Desai R. , Reading J.M. , Hasanaj K. , Wang S.D. , Carden L.B. , Wolter M. , Hickey B. , Lee J. , et al. .
Source: Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer, 2025-01-06 00:00:00.0; 33(1), p. 72.
EPub date: 2025-01-06 00:00:00.0.
PMID: 39762596
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Effect of the Fit2Thrive Intervention on Patient-reported Outcomes in Breast Cancer Survivors: A Randomized Full Factorial Trial.
Authors: Solk P. , Song J. , Welch W.A. , Spring B. , Cella D. , Penedo F. , Ackermann R. , Courneya K.S. , Siddique J. , Freeman H. , et al. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2023-08-21 00:00:00.0; 57(9), p. 765-776.
PMID: 37203237
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Optimization of a technology-supported physical activity promotion intervention for breast cancer survivors: Results from Fit2Thrive.
Authors: Phillips S.M. , Penedo F.J. , Collins L.M. , Solk P. , Siddique J. , Song J. , Cella D. , Courneya K.S. , Ackermann R.T. , Welch W.A. , et al. .
Source: Cancer, 2021-11-23 00:00:00.0; , .
EPub date: 2021-11-23 00:00:00.0.
PMID: 34812521
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