Grant Details
Grant Number: |
5R21CA219028-02 Interpret this number |
Primary Investigator: |
Phillips, Siobhan |
Organization: |
Northwestern University At Chicago |
Project Title: |
Incorporating Biomarkers of Prognosis and Cardiovascular Disease Risk in the Fit2thrive Physical Activity Promotion Intervention for Breast Cancer Survivors |
Fiscal Year: |
2019 |
Abstract
PROJECT SUMMARY/ABSTRACT
Higher physical activity (PA) is associated with reduced risk of breast cancer (BC) recurrence and progression
and increased survival. Increased PA is also associated with reductions in cardiovascular disease (CVD)
mortality, the leading cause of non-cancer mortality among BC survivors (BCS). PA may prevent BC
progression and CVD via its effects on inflammation and also decrease CVD risk via effects on cardiometabolic
biomarkers. However, the exact biologic mechanisms are poorly understood as few PA interventions include
biomarkers of BC progression or CVD risk. Additionally, most PA interventions are costly, intense, on-site
multicomponent interventions that provide little insight into what components (i.e. phone calls, Fitbits, etc.) are,
or are not, effective, and traditional venous blood sample collection is often costly and requires lab visits
limiting the potential public health impact of this research. In order to increase
Publications
None