||1R01CA234205-01A1 Interpret this number
||University Of Texas Hlth Sci Ctr Houston
||Age of Initiation of Tobacco Products Among Usa Youth and Young Adults
The Surgeon General's 2012 report provided data that the initiation of cigarette smoking begins before
adulthood. Considering the new and emerging tobacco products available, estimating the age and onset of
initiation, changing patterns of tobacco use and correlates of tobacco use among U.S. youth and young adults
is paramount to informing contemporary tobacco regulatory science. We will directly inform the Food and Drug
Administration (FDA) authority on tobacco regulation about all tobacco products to protect the public’s health.
This project directly address the FDA's research priority areas that focus on understanding the knowledge,
attitudes, and behaviors that contribute to tobacco product (TP) initiation, age of TP initiation, and factors
associated with age of initiation. Our study involves a prospective secondary analysis of the first three waves of
the Population Assessment of Tobacco and Health (PATH) study among U.S. youth (12-17 years old) and
young adults (18-24 years old) who reported never use at baseline. Six TPs will be considered: cigarettes, e-
cigarettes, cigars (i.e. traditional cigars, cigarillo, filtered cigars), hookah; smokeless tobacco, and any of these
TPs. Seven outcomes are considered for each TP: age to first report ever or past 30-day use, age to become
susceptible to use, age to be an established user (i.e. ever use fairly regularly), age to first report dual/poly TP
use, age to first use flavored TP, and age of ever combustible use. There is a gap in the knowledge related to
the age of first reporting of each one of the seven outcomes prospectively and with contemporary data. This
project has three aims. Aim 1: Among youth ages 12-17 years old who are never users of TPs at wave 1, to
estimate prospectively their age of initiation of TPs and to identify the risk factors associated with the age of
initiation of cigarettes and each one of the NCTPs: e-cigarettes, cigars, hookah, and smokeless tobacco. Aim
2: same as aim 1 but among young adults ages 18-24 years old who are never users of TPs at wave 1. Aim 3:
Among youth and young adults ages 12-24 who are never users of TPs at wave 1, to identify the trajectories
and transitions in the onset of TPs across time, from wave 1 to waves 2 and 3, and to identify the risk factors
associated with these trajectories and transitions. We plan to explore socio-demographic, interpersonal,
intrapersonal, social, and environmental factors potentially associated with the age of initiation of the different
TPs. Consistent with research priorities FDA has set forth, this project focuses on our understanding of the
knowledge and behaviors to best predict age of initiation. Few studies can test hypotheses with longitudinal
data that span youth and young adults. This project strengthens the evidence for tobacco regulatory science by
expanding the evidence regarding emerging tobacco products, using a national longitudinal study, and taking
advantage of contemporary data that reflects the evolving tobacco product landscape. This project addresses
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