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Grant Details

Grant Number: 5R01CA198971-04 Interpret this number
Primary Investigator: Buman, Matthew
Organization: Arizona State University-Tempe Campus
Project Title: Stand and Move at Work: a Group-Randomized Trial
Fiscal Year: 2018


 DESCRIPTION (provided by applicant): The health benefits of moderate-vigorous physical activity are well-established across the lifespan and progress is being made to help Americans achieve the 2008 Physical Activity Guidelines for Americans of 150 minutes/week of moderate-vigorous physical activity. However, Physical Activity Guidelines also state the need to "minimize the amount of time spent being sedentary for extended periods"; yet adults spend an average of 7.5 h/day being sedentary (i.e., sitting). Our preliminary studies suggest reallocating just 30 min/day from sedentary to light-intensity physical activity, holding moderate-vigorous physical activity constant, can significantly improve health risks. The workplace is the ideal context to reduce sedentary behavior given that American workers spend 70-80% of their workday sitting at a desk. Indeed, our preliminary studies suggest that small but cumulative changes in posture and light-intensity physical activity can be achieved without interfering with daily tasks and productivity. Strategies to reduce sitting and increase light-intensity physical activity in the workplace have been promising but are limited by small sample size, short duration, and non- randomized designs. This project aims to test the relative efficacy of two interventions in 24 worksites across two states (N=720 workers). The MOVE intervention is a multilevel individual, social, environmental, and organizational intervention targeting increases i light-intensity physical activity in the workplace. The STAND&MOVE intervention is the MOVE intervention in addition to the installation and use of sit-stand workstations to reduce sitting an enhance light-intensity physical activity opportunities. Our primary outcome will be objectively-measured changes in light-intensity physical activity and sitting over 12 months, with additional process measures at 6 months and longer-term sustainability outcomes at 24 months. Our secondary outcome will be cardiometabolic risk using a composite measure of fasting glucose, insulin, triglycerides, HDL-cholesterol, and blood pressure over the same time points. Unique features of this application are the group-randomized design, which to our knowledge has yet to be used to test the efficacy of sit-stand workstations in the adult workforce, precise measurement of workplace posture and activity, geographical and workplace diversity across two states (Arizona and Minnesota), diverse investigator team of exercise physiologists, wellness professionals, epidemiologists, and biostatisticians, and strong potential for immediate dissemination and broad implementation due to the real-word setting and high level of generalizability. This project stands to be the most definitive study to date on the efficacy and effectiveness of multi-level workplace interventions to increase light-intensity physical activity, reduce sitting, and improve cardiometabolic health.


Effect of Weight Goals on Sitting and Moving During a Worksite Sedentary Time Reduction Intervention.
Authors: Leonard K.S. , de Brito J.N. , Larouche M.L. , Rydell S.A. , Mitchell N.R. , Pereira M.A. , Buman M.P. .
Source: Translational journal of the American College of Sports Medicine, 2022 Fall; 7(4), .
EPub date: 2022-09-15.
PMID: 36213514
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Cost and cost-effectiveness of the 'Stand and Move at Work' multicomponent intervention to reduce workplace sedentary time and cardiometabolic risk.
Authors: Michaud T.L. , You W. , Estabrooks P.A. , Leonard K. , Rydell S.A. , Mullane S.L. , Pereira M.A. , Buman M.P. .
Source: Scandinavian journal of work, environment & health, 2022-07-01; 48(5), p. 399-409.
EPub date: 2022-03-25.
PMID: 35333373
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Qualitative comparative analysis of the implementation fidelity of a workplace sedentary reduction intervention.
Authors: Leonard K.S. , Mullane S.L. , Golden C.A. , Rydell S.A. , Mitchell N.R. , Koskan A. , Estabrooks P.A. , Pereira M.A. , Buman M.P. .
Source: BMC public health, 2022-05-31; 22(1), p. 1086.
EPub date: 2022-05-31.
PMID: 35641923
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Acute Effect of Height-Adjustable Workstations on Blood Glucose Levels in Women With Impaired Fasting Glucose Levels While Working: A Pilot Study.
Authors: Bonikowske A.R. , Carpenter K.C. , Stovitz S.D. , Bandyopadhyay D. , Pereira M.A. , Lewis B.A. .
Source: Translational journal of the American College of Sports Medicine, 2021 Fall; 6(4), .
EPub date: 2021-08-27.
PMID: 35668746
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Efficacy of the 'Stand and Move at Work' multicomponent workplace intervention to reduce sedentary time and improve cardiometabolic risk: a group randomized clinical trial.
Authors: Pereira M.A. , Mullane S.L. , Toledo M.J.L. , Larouche M.L. , Rydell S.A. , Vuong B. , Feltes L.H. , Mitchell N.R. , de Brito J.N. , Hasanaj K. , et al. .
Source: The international journal of behavioral nutrition and physical activity, 2020-10-27; 17(1), p. 133.
EPub date: 2020-10-27.
PMID: 33109190
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Stand and Move at Work sedentary behavior questionnaire: validity and sensitivity to change.
Authors: Toledo M.J.L. , Mullane S.L. , Larouche M.L. , Rydell S.A. , Mitchell N.R. , Pereira M.A. , Buman M.P. .
Source: Annals of epidemiology, 2019 Mar; 31, p. 62-68.e1.
EPub date: 2019-01-11.
PMID: 30718055
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Enrollment Strategies, Barriers to Participation, and Reach of a Workplace Intervention Targeting Sedentary Behavior.
Authors: Mullane S.L. , Rydell S.A. , Larouche M.L. , Toledo M.J.L. , Feltes L.H. , Vuong B. , Crespo N.C. , Gaesser G.A. , Estabrooks P.A. , Pereira M.A. , et al. .
Source: American journal of health promotion : AJHP, 2019 Feb; 33(2), p. 225-236.
EPub date: 2018-07-09.
PMID: 29986592
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Using Point-of-Choice Prompts to Reduce Sedentary Behavior in Sit-Stand Workstation Users.
Authors: Larouche M.L. , Mullane S.L. , Toledo M.J.L. , Pereira M.A. , Huberty J.L. , Ainsworth B.E. , Buman M.P. .
Source: Frontiers in public health, 2018; 6, p. 323.
EPub date: 2018-11-21.
PMID: 30525017
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Wearable Technology and Physical Activity in Chronic Disease: Opportunities and Challenges.
Authors: Phillips S.M. , Cadmus-Bertram L. , Rosenberg D. , Buman M.P. , Lynch B.M. .
Source: American journal of preventive medicine, 2018 Jan; 54(1), p. 144-150.
EPub date: 2017-11-06.
PMID: 29122356
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Social ecological correlates of workplace sedentary behavior.
Authors: Mullane S.L. , Toledo M.J.L. , Rydell S.A. , Feltes L.H. , Vuong B. , Crespo N.C. , Pereira M.A. , Buman M.P. .
Source: The international journal of behavioral nutrition and physical activity, 2017-08-31; 14(1), p. 117.
EPub date: 2017-08-31.
PMID: 28859679
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Targeting Reductions in Sitting Time to Increase Physical Activity and Improve Health.
Authors: Keadle S.K. , Conroy D.E. , Buman M.P. , Dunstan D.W. , Matthews C.E. .
Source: Medicine and science in sports and exercise, 2017 Aug; 49(8), p. 1572-1582.
PMID: 28272267
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An intervention to reduce sitting and increase light-intensity physical activity at work: Design and rationale of the 'Stand & Move at Work' group randomized trial.
Authors: Buman M.P. , Mullane S.L. , Toledo M.J. , Rydell S.A. , Gaesser G.A. , Crespo N.C. , Hannan P. , Feltes L. , Vuong B. , Pereira M.A. .
Source: Contemporary clinical trials, 2017 Feb; 53, p. 11-19.
EPub date: 2016-12-07.
PMID: 27940181
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Reallocating Time to Sleep, Sedentary Time, or Physical Activity: Associations with Waist Circumference and Body Mass Index in Breast Cancer Survivors.
Authors: Boyle T. , Vallance J.K. , Buman M.P. , Lynch B.M. .
Source: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2017 Feb; 26(2), p. 254-260.
EPub date: 2016-10-25.
PMID: 27780817
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BeWell24: development and process evaluation of a smartphone "app" to improve sleep, sedentary, and active behaviors in US Veterans with increased metabolic risk.
Authors: Buman M.P. , Epstein D.R. , Gutierrez M. , Herb C. , Hollingshead K. , Huberty J.L. , Hekler E.B. , Vega-López S. , Ohri-Vachaspati P. , Hekler A.C. , et al. .
Source: Translational behavioral medicine, 2016 Sep; 6(3), p. 438-48.
PMID: 27528532
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Free-living cross-comparison of two wearable monitors for sleep and physical activity in healthy young adults.
Authors: Cellini N. , McDevitt E.A. , Mednick S.C. , Buman M.P. .
Source: Physiology & behavior, 2016-04-01; 157, p. 79-86.
EPub date: 2016-01-25.
PMID: 26821185
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