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Grant Details

Grant Number: 5R21CA212201-02 Interpret this number
Primary Investigator: Linos, Eleni
Organization: University Of California, San Francisco
Project Title: Online Advertising for Skin Cancer Prevention
Fiscal Year: 2018


Abstract/Executive Summary Skin cancer is the most common cancer – more common than all other cancers combined. Despite public health efforts, melanoma rates are still increasing. The proposed research addresses this important problem using an innovative approach: using online advertising and social media to target groups at risk of skin cancer. Additionally, it addresses health disparities by focusing on gay men, who are an understudied, high-risk population. Finally, our novel approach allows for unprecedented reach at relatively low intervention cost. Our team has extensive experience with observational and interventional behavioral research using social media as well as significant experience working with sexual minority men. Our central hypothesis is that targeted online prevention messages can influence knowledge, attitudes, and behaviors about tanning among gay men. The rationale underlying this research is that one of the groups at highest risk of developing melanoma from tanning bed exposure – gay men – is engaged on social media, so this is the platform to best reach them. In Aim 1, we will identify which melanoma prevention messages are most effective for gay men. Using focus groups, cognitive interviews, and online response data, we will determine the most persuasive messages that motivate gay men to avoid tanning beds. In Aim 2, we will assess the impact of melanoma prevention messages on knowledge and behaviors relevant to melanoma risk and on self-reported intent to use tanning beds, which is a validated proxy for tanning behavior. We will first optimize the delivery of our prevention messages by assessing how timing (season and time of day), frequency, and number of messages impact engagement with a prevention message: including number of views and clicks that direct to a website with melanoma prevention information. We will then test the effect of prevention messages by performing a rapid, randomized, controlled trial on Facebook (using the most effective messages identified in Aim 1) placed as advertisements. The intervention group and control group will each include 3,600 gay men, for a total study population of 7,200 gay men. These specific aims have been designed to provide the essential feasibility and preliminary efficacy data to support future large-scale and long-term research on the impact of targeted online prevention messages on hard outcomes, such as reductions in actual tanning bed use and decreases in state-specific melanoma incidence.


Development of a patient decision aid for the management of superficial basal cell carcinoma (BCC) in adults with a limited life expectancy.
Authors: Junn A. , Shukla N.R. , Morrison L. , Halley M. , Chren M.M. , Walter L.C. , Frosch D.L. , Matlock D. , Torres J.S. , Linos E. .
Source: BMC medical informatics and decision making, 2020-04-29; 20(1), p. 81.
EPub date: 2020-04-29.
PMID: 32349762
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Authors: Dessinioti C. , Dimou N. , Geller A.C. , Stergiopoulou A. , Lo S. , Keim U. , Gershenwald J.E. , Haydu L.E. , Ribero S. , Quaglino P. , et al. .
Source: Journal of the National Cancer Institute, 2019-12-01; 111(12), p. 1314-1322.
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Association of Number of Indoor Tanning Salons With Neighborhoods With Higher Concentrations of Male-Male Partnered Households.
Authors: Chen R. , Hipp J.A. , Morrison L. , Henriksen L. , Swetter S.M. , Linos E. .
Source: JAMA network open, 2019-10-02; 2(10), p. e1912443.
EPub date: 2019-10-02.
PMID: 31584678
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Facebook advertising for cancer prevention: a pilot study.
Authors: Morrison L. , Chen C. , Torres J.S. , Wehner M. , Junn A. , Linos E. .
Source: The British journal of dermatology, 2019 10; 181(4), p. 858-859.
EPub date: 2019-09-04.
PMID: 30972743
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Knowledge, Motivations, and Practices Regarding Indoor Tanning Among Men Who Have Sex With Men in the San Francisco Bay Area.
Authors: Morrison L. , Raymond H.F. , Katz K.A. , Simard J. , Admassu N. , Pascua N. , Linos E. .
Source: JAMA dermatology, 2019-07-01; 155(7), p. 852-854.
PMID: 31090875
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Decisions and repercussions of second victim experiences for mothers in medicine (SAVE DR MoM).
Authors: Gupta K. , Lisker S. , Rivadeneira N.A. , Mangurian C. , Linos E. , Sarkar U. .
Source: BMJ quality & safety, 2019 07; 28(7), p. 564-573.
EPub date: 2019-02-04.
PMID: 30718333
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Motivations among sexual-minority men for starting and stopping indoor tanning.
Authors: Admassu N. , Pimentel M.A. , Halley M.C. , Torres J. , Pascua N. , Katz K.A. , Linos E. .
Source: The British journal of dermatology, 2019 06; 180(6), p. 1529-1530.
EPub date: 2019-02-27.
PMID: 30671929
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Prevalence of Atopic Eczema Among Patients Seen in Primary Care: Data From The Health Improvement Network.
Authors: Abuabara K. , Magyari A. , McCulloch C.E. , Linos E. , Margolis D.J. , Langan S.M. .
Source: Annals of internal medicine, 2019-03-05; 170(5), p. 354-356.
EPub date: 2018-12-04.
PMID: 30508419
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Outcomes and Risk Factors in Patients with Multiple Primary Melanomas.
Authors: Nosrati A. , Yu W.Y. , McGuire J. , Griffin A. , de Souza J.R. , Singh R. , Linos E. , Chren M.M. , Grimes B. , Jewell N.P. , et al. .
Source: The Journal of investigative dermatology, 2019 01; 139(1), p. 195-201.
EPub date: 2018-07-19.
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Physician mothers' experience of workplace discrimination: a qualitative analysis.
Authors: Halley M.C. , Rustagi A.S. , Torres J.S. , Linos E. , Plaut V. , Mangurian C. , Choo E. , Linos E. .
Source: BMJ (Clinical research ed.), 2018-12-12; 363, p. k4926.
EPub date: 2018-12-12.
PMID: 30541926
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Sunscreens, cancer, and protecting our planet.
Authors: Galamgam J. , Linou N. , Linos E. .
Source: The Lancet. Planetary health, 2018 11; 2(11), p. e465-e466.
PMID: 30396433
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Characteristics and Skin Cancer Risk Behaviors of Adult Sunless Tanners in the United States.
Authors: Dodds M. , Arron S.T. , Linos E. , Polcari I. , Mansh M.D. .
Source: JAMA dermatology, 2018-09-01; 154(9), p. 1066-1071.
PMID: 30046802
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Natural history of lesions suspicious for basal cell carcinoma in older adults in Ikaria, Greece.
Authors: Wehner M.R. , Dalma N. , Landefeld C. , Pare-Anastasiadou A. , Koutelidas I. , Chren M.M. , Aji N. , Teng C.E. , Koenig B.A. , Tang J. , et al. .
Source: The British journal of dermatology, 2018 09; 179(3), p. 767-768.
EPub date: 2018-07-12.
PMID: 29741766
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Skin cancer prevention messages on Facebook: Likes, shares, and comments.
Authors: Nosrati A. , Pimentel M.A. , Falzone A. , Hegde R. , Goel S. , Chren M.M. , Eye R. , Linos E. , Pagoto S. , Walkosz B.J. .
Source: Journal of the American Academy of Dermatology, 2018 Sep; 79(3), p. 582-585.e1.
EPub date: 2018-03-05.
PMID: 29518459
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Geriatric Dermatology-A Framework for Caring for Older Patients With Skin Disease.
Authors: Linos E. , Chren M.M. , Covinsky K. .
Source: JAMA dermatology, 2018-07-01; 154(7), p. 757-758.
PMID: 29710117
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Using Social Media to Target Cancer Prevention in Young Adults: Viewpoint.
Authors: Sarkar U. , Le G.M. , Lyles C.R. , Ramo D. , Linos E. , Bibbins-Domingo K. .
Source: Journal of medical Internet research, 2018-06-05; 20(6), p. e203.
EPub date: 2018-06-05.
PMID: 29871850
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USPSTF Recommendations for Behavioral Counseling for Skin Cancer Prevention: Throwing Shade on UV Radiation.
Authors: Linos E. , Pagoto S. .
Source: JAMA internal medicine, 2018-05-01; 178(5), p. 609-611.
PMID: 29558531
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Dermatology on Instagram: An Analysis of Hashtags.
Authors: Park J.H. , Christman M.P. , Linos E. , Rieder E.A. .
Source: Journal of drugs in dermatology : JDD, 2018-04-01; 17(4), p. 482-484.
PMID: 29601627
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Indoor Tanning, Sunless Tanning, and Sun-Protection Behaviors Among Sexual Minority Men.
Authors: Gao Y. , Arron S.T. , Linos E. , Polcari I. , Mansh M.D. .
Source: JAMA dermatology, 2018-04-01; 154(4), p. 477-479.
PMID: 29490367
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All-cause mortality in patients with basal and squamous cell carcinoma: A systematic review and meta-analysis.
Authors: Wehner M.R. , Cidre Serrano W. , Nosrati A. , Schoen P.M. , Chren M.M. , Boscardin J. , Linos E. .
Source: Journal of the American Academy of Dermatology, 2018 04; 78(4), p. 663-672.e3.
EPub date: 2017-11-13.
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Paid Family and Childbearing Leave Policies at Top US Medical Schools.
Authors: Riano N.S. , Linos E. , Accurso E.C. , Sung D. , Linos E. , Simard J.F. , Mangurian C. .
Source: JAMA, 2018-02-13; 319(6), p. 611-614.
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Diversity in the dermatology workforce: 2017 status update.
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Source: Cutis, 2017 12; 100(6), p. 352-353.
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Acne, sexual orientation, and mental health among young adults in the United States: A population-based, cross-sectional study.
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Source: Journal of the American Academy of Dermatology, 2017 11; 77(5), p. 971-973.
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Types of Shade Vary in Protection Just Like Sunscreens.
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Teens, Tweets, and Tanning Beds: Rethinking the Use of Social Media for Skin Cancer Prevention.
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Source: American journal of preventive medicine, 2017 Sep; 53(3S1), p. S86-S94.
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