Grant Details
Grant Number: |
5R25EB023928-02 Interpret this number |
Primary Investigator: |
Owzar, Kouros |
Organization: |
Duke University |
Project Title: |
A Hands-on, Integrative Next-Generation Sequencing Course: Design, Experiment, and Analysis |
Fiscal Year: |
2017 |
Abstract
PROJECT SUMMARY/ABSTRACT
The proposed six-week summer course will provide knowledge, practical skills and experience needed to train
the next generation of biomedical researcher in planning, conducting and analyzing inter-disciplinary genomics
experiments. Participants will be recruited nationally from advanced undergraduates, early graduate students
and postdoctoral fellows from both biological and quantitative disciplines. In addition to learning genomics,
statistics, informatics and programming from didactic lectures, participants will also gain invaluable experience
working in small diverse groups, mentored by faculty instructors with expertise in both the biological and
quantitative sciences. The workshop emphasizes recall and self-testing in gaining these skills in the hands-on
computing and wet lab sessions, following pedagogical best practices of interleaved learning, spacing and low-
stakes testing for learning. The workshop also emphasizes best practices in reproducible analysis, including
literate programming, use of version control and automation via scripting from raw data to final report. Finally,
students will be introduced to platforms for Big Data, including the use of cloud computing platforms and libraries
for distributed computing such as Spark.
Publications
Comparative analysis of RNA enrichment methods for preparation of Cryptococcus neoformans RNA sequencing libraries.
Authors: Telzrow C.L.
, Zwack P.J.
, Esher Righi S.
, Dietrich F.S.
, Chan C.
, Owzar K.
, Alspaugh J.A.
, Granek J.A.
.
Source: G3 (bethesda, Md.), 2021-08-26 00:00:00.0; , .
EPub date: 2021-08-26 00:00:00.0.
PMID: 34518880
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