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Grant Details

Grant Number: 5P50CA180908-05 Interpret this number
Primary Investigator: Wewers, Mary
Organization: Ohio State University
Project Title: Osu Center of Excellence in Regulatory Tobacco Science (Osu-Certs)
Fiscal Year: 2017
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Abstract

DESCRIPTION (provided by applicant): The overall vision of The Ohio State University Center of Excellence in Regulatory Tobacco Science (OSU-CERTS) is to serve as a national leader in providing relevant scientific data to support FDA regulatory decision making in the Center for Tobacco Products. The overall theme of OSU-CERTS is to understand the reasons for underlying tobacco-product preferences, especially dual and poly-use, and how these reasons influence use in an environment of ever-changing diverse types of tobacco products. The Center will integrate this theme in a series of adolescent and adult cohort studies conducted in natural settings, complemented by well-controlled experimental studies that allow for causal inference, the OSU-CERTS includes projects with shared cohorts, theory, and/or measures; all projects will provide data for urban and rural settings to enhance generalizability. Included are four projects, all sampled from the same methodology (address based sampling), where some households will be shared by companion projects and other households will be used for other projects. Companion Projects 1 and 2 will utilize a three year cohort of adolescents and their families to compare and establish the prevalence of smoking, ST use and dual use, and tobacco-use risk factors with an emphasis on environment, advertising and marketing, and trajectories to regular use. This cohort study will include an assessment of carcinogen exposure, and genetics for taste perception and tobacco use behavior. Project 3 will establish a 3 year cohort of adults to characterize the diversity of types of tobacco products used overtime and examine individual, cognitive and affective risk factors. It will consider purchasing factors and marketing practices in retail environments. Project 4 will be several experimental studies that examine psychological constructs and decision making models for choosing tobacco products. The OSU-CERTS includes five cores (A-E) to provide resources to all projects. Cores include: 1) Administrative (Core A); 2) Recruitment, Survey and Retention (Core B); 3) Biostatistics and Data Resources (Core C); 4) Developmental and Pilot Research (Core D); and 5) Research Training and Education (Core E). The OSU-CERTS infrastructure and cores will set the foundation for current and future scientific discoveries that will assist th FDA. It currently addresses 11 of 56 research priorities set forth by the FDA in January, 2012. Institutional commitment includes recruitment of new faculty and funding for junior faculty, postdoctoral fellows and pilot projects. OSU-CERTS is an investment that trains the next generation of scientists and policy experts, funds innovative pilot projects and establishes relevant cohorts. RELEVANCE: OSU-CERTS will assist to improve public health and reduce population harm from tobacco product use. Harm involves individual disease risk and prevalence of product use. OSU-CERTS will conduct a series of projects to provide information about the relationships between ever-changing diverse types of tobacco product use among rural (Appalachian OH) and urban (Columbus OH) adolescents and adults at risk for tobacco-attributable disease and death. This information assists the FDA to regulate harmful products.

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Publications

Examining the relationship between pregnancy and quitting use of tobacco products in a U.S. national sample of women of reproductive age.
Authors: Kurti A.N. , Redner R. , Bunn J.Y. , Tang K. , Nighbor T. , Lopez A.A. , Keith D.R. , Villanti A.C. , Stanton C.A. , Gaalema D.E. , et al. .
Source: Preventive Medicine, 2018 Dec; 117, p. 52-60.
EPub date: 2018-08-23 00:00:00.0.
PMID: 30145348
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Tobacco Product Harm Perceptions and New Use.
Authors: Parker M.A. , Villanti A.C. , Quisenberry A.J. , Stanton C.A. , Doogan N.J. , Redner R. , Gaalema D.E. , Kurti A.N. , Nighbor T. , Roberts M.E. , et al. .
Source: Pediatrics, 2018-11-05 00:00:00.0; , .
EPub date: 2018-11-05 00:00:00.0.
PMID: 30397167
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Tobacco and Alcohol on Television: A Content Analysis of Male Adolescents' Favorite Shows.
Authors: Keller-Hamilton B. , Muff J. , Blue T. , Lu B. , Slater M.D. , Roberts M.E. , Ferketich A.K. .
Source: Preventing Chronic Disease, 2018-11-01 00:00:00.0; 15, p. E134.
EPub date: 2018-11-01 00:00:00.0.
PMID: 30388067
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Odds ratios from logistic, geometric, Poisson, and negative binomial regression models.
Authors: Sroka C.J. , Nagaraja H.N. .
Source: Bmc Medical Research Methodology, 2018-10-20 00:00:00.0; 18(1), p. 112.
EPub date: 2018-10-20 00:00:00.0.
PMID: 30342488
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Pictorial Warning Labels and Memory for Cigarette Health-risk Information Over Time.
Authors: Peters E. , Shoots-Reinhard B. , Evans A.T. , Shoben A. , Klein E. , Tompkins M.K. , Romer D. , Tusler M. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2018-06-11 00:00:00.0; , .
EPub date: 2018-06-11 00:00:00.0.
PMID: 29947729
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Tobacco use in cardiac patients: Perceptions, use, and changes after a recent myocardial infarction among US adults in the PATH study (2013-2015).
Authors: Gaalema D.E. , Pericot-Valverde I. , Bunn J.Y. , Villanti A.C. , Cepeda-Benito A. , Doogan N.J. , Keith D.R. , Kurti A.N. , Lopez A.A. , Nighbor T. , et al. .
Source: Preventive Medicine, 2018-05-08 00:00:00.0; , .
EPub date: 2018-05-08 00:00:00.0.
PMID: 29746974
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Warning Size Affects What Adolescents Recall From Tobacco Advertisements.
Authors: Evans A.T. , Peters E. , Keller-Hamilton B. , Loiewski C. , Slater M.D. , Lu B. , Roberts M.E. , Ferketich A.K. .
Source: Tobacco Regulatory Science, 2018 May; 4(3), p. 79-87.
PMID: 30009217
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Impact of Presence of Children on Indoor Tobacco Restrictions in Households of Urban and Rural Adult Tobacco Users.
Authors: Kopp B.T. , Hinton A. , Lu R. , Cooper S. , Nagaraja H. , Wewers M.E. .
Source: Academic Pediatrics, 2018-04-10 00:00:00.0; , .
EPub date: 2018-04-10 00:00:00.0.
PMID: 29653256
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Trend differences in men and women in rural and urban U.S. settings.
Authors: Cepeda-Benito A. , Doogan N.J. , Redner R. , Roberts M.E. , Kurti A.N. , Villanti A.C. , Lopez A.A. , Quisenberry A.J. , Stanton C.A. , Gaalema D.E. , et al. .
Source: Preventive Medicine, 2018-04-05 00:00:00.0; , .
EPub date: 2018-04-05 00:00:00.0.
PMID: 29627511
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The role of travel distance and price promotions in tobacco product purchase quantity.
Authors: Doogan N.J. , Cooper S. , Quisenberry A.J. , Brasky T.M. , Browning C.R. , Klein E.G. , Hinton A. , Nagaraja H.N. , Xi W. , Wewers M.E. .
Source: Health & Place, 2018-04-03 00:00:00.0; 51, p. 151-157.
EPub date: 2018-04-03 00:00:00.0.
PMID: 29625358
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Tobacco and nicotine delivery product use in a U.S. national sample of women of reproductive age.
Authors: Lopez A.A. , Redner R. , Kurti A.N. , Keith D.R. , Villanti A.C. , Stanton C.A. , Gaalema D.E. , Bunn J.Y. , Doogan N.J. , Cepeda-Benito A. , et al. .
Source: Preventive Medicine, 2018-03-17 00:00:00.0; , .
EPub date: 2018-03-17 00:00:00.0.
PMID: 29559222
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Don't throw the baby out with the bath water: Commentary on Kok, Peters, Kessels, ten Hoor, and Ruiter (2018).
Authors: Peters E. , Shoots-Reinhard B. .
Source: Health Psychology Review, 2018-03-13 00:00:00.0; , p. 1-4.
EPub date: 2018-03-13 00:00:00.0.
PMID: 29478394
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Effective Formats for Communicating Risks from Cigarette Smoke Chemicals.
Authors: Byron M.J. , Lazard A.J. , Peters E. , Vu H. , Schmidt A. , Brewer N.T. .
Source: Tobacco Regulatory Science, 2018 Mar; 4(2), p. 16-29.
PMID: 30288395
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Attitudes toward Tobacco, Alcohol, and Non-Alcoholic Beverage Advertisement Themes among Adolescent Boys.
Authors: Friedman K.L. , Roberts M.E. , Keller-Hamilton B. , Yates K.A. , Paskett E.D. , Berman M.L. , Slater M.D. , Lu B. , Ferketich A.K. .
Source: Substance Use & Misuse, 2018-02-13 00:00:00.0; , p. 1-9.
EPub date: 2018-02-13 00:00:00.0.
PMID: 29436898
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Advancing Tobacco Product Warning Labels Research Methods and Theory: A Summary of a Grantee Meeting Held by the US National Cancer Institute.
Authors: Thrasher J.F. , Brewer N.T. , Niederdeppe J. , Peters E. , Strasser A.A. , Grana R. , Kaufman A.R. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2018-02-10 00:00:00.0; , .
EPub date: 2018-02-10 00:00:00.0.
PMID: 29444268
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Characteristics of the Tobacco User Adult Cohort in Urban and Rural Ohio.
Authors: Brasky T.M. , Hinton A. , Doogan N.J. , Cooper S.E. , Nagaraja H.N. , Xi W. , Shields P.G. , Wewers M.E. .
Source: Tobacco Regulatory Science, 2018 Jan; 4(1), p. 614-630.
EPub date: 2018-01-01 00:00:00.0.
PMID: 29862311
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Website Designs for Communicating About Chemicals in Cigarette Smoke.
Authors: Lazard A.J. , Byron M.J. , Vu H. , Peters E. , Schmidt A. , Brewer N.T. .
Source: Health Communication, 2017-12-13 00:00:00.0; , p. 1-10.
EPub date: 2017-12-13 00:00:00.0.
PMID: 29236552
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Cigarette Filter Ventilation and its Relationship to Increasing Rates of Lung Adenocarcinoma.
Authors: Song M.A. , Benowitz N.L. , Berman M. , Brasky T.M. , Cummings K.M. , Hatsukami D.K. , Marian C. , O'Connor R. , Rees V.W. , Woroszylo C. , et al. .
Source: Journal Of The National Cancer Institute, 2017-12-01 00:00:00.0; 109(12), .
PMID: 28525914
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Young Adult Perceptions Surrounding Hookah Use.
Authors: Roberts M.E. , Klein E.G. , Berman M.L. , Berhane B. , Ferketich A.K. .
Source: Health Behavior And Policy Review, 2017 Nov; 4(6), p. 593-600.
PMID: 29152524
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The association between parental history and delay discounting among individuals in recovery from addiction.
Authors: Athamneh L.N. , Stein J.S. , Quisenberry A.J. , Pope D. , Bickel W.K. .
Source: Drug And Alcohol Dependence, 2017-10-01 00:00:00.0; 179, p. 153-158.
EPub date: 2017-07-29 00:00:00.0.
PMID: 28780380
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The Experimental Tobacco Marketplace II: Substitutability and sex effects in dual electronic cigarette and conventional cigarette users.
Authors: Quisenberry A.J. , Koffarnus M.N. , Epstein L.H. , Bickel W.K. .
Source: Drug And Alcohol Dependence, 2017-09-01 00:00:00.0; 178, p. 551-555.
EPub date: 2017-07-05 00:00:00.0.
PMID: 28732318
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Rural Versus Urban Use of Traditional and Emerging Tobacco Products in the United States, 2013-2014.
Authors: Roberts M.E. , Doogan N.J. , Stanton C.A. , Quisenberry A.J. , Villanti A.C. , Gaalema D.E. , Keith D.R. , Kurti A.N. , Lopez A.A. , Redner R. , et al. .
Source: American Journal Of Public Health, 2017-08-17 00:00:00.0; , p. e1-e6.
EPub date: 2017-08-17 00:00:00.0.
PMID: 28817323
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Tobacco and nicotine delivery product use in a national sample of pregnant women.
Authors: Kurti A.N. , Redner R. , Lopez A.A. , Keith D.R. , Villanti A.C. , Stanton C.A. , Gaalema D.E. , Bunn J.Y. , Doogan N.J. , Cepeda-Benito A. , et al. .
Source: Preventive Medicine, 2017-08-05 00:00:00.0; , .
EPub date: 2017-08-05 00:00:00.0.
PMID: 28789981
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Tracking Young Adults' Attitudes Toward Tobacco Marketing Using Ecological Momentary Assessment (EMA).
Authors: Roberts M.E. , Lu B. , Browning C.R. , Ferketich A.K. .
Source: Substance Use & Misuse, 2017-07-29 00:00:00.0; 52(9), p. 1219-1224.
EPub date: 2017-06-12 00:00:00.0.
PMID: 28605315
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A Review of Pulmonary Toxicity of Electronic Cigarettes In The Context of Smoking: A Focus On Inflammation.
Authors: Shields P.G. , Berman M. , Brasky T.M. , Freudenheim J.L. , Mathe E.A. , McElroy J. , Song M.A. , Wewers M.D. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2017-06-22 00:00:00.0; , .
EPub date: 2017-06-22 00:00:00.0.
PMID: 28642230
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Effects of Pictorial Warning Labels for Cigarettes and Quit-Efficacy on Emotional Responses, Smoking Satisfaction, and Cigarette Consumption.
Authors: Romer D. , Ferguson S.G. , Strasser A.A. , Evans A.T. , Tompkins M.K. , Macisco J. , Fardal M. , Tusler M. , Peters E. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2017-05-09 00:00:00.0; , .
EPub date: 2017-05-09 00:00:00.0.
PMID: 28488230
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Evidentiary Support in Public Comments to the FDA's Center for Tobacco Products.
Authors: Hemmerich N. , Klein E.G. , Berman M. .
Source: Journal Of Health Politics, Policy And Law, 2017-05-08 00:00:00.0; , .
EPub date: 2017-05-08 00:00:00.0.
PMID: 28483810
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Self-Regulation Principles Underlying Risk Perception and Decision Making within the Context of Genomic Testing.
Authors: Cameron L.D. , Biesecker B.B. , Peters E. , Taber J.M. , Klein W.M.P. .
Source: Social And Personality Psychology Compass, 2017 May; 11(5), .
EPub date: 2017-05-05 00:00:00.0.
PMID: 29225669
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Cigarette graphic warning labels increase both risk perceptions and smoking myth endorsement.
Authors: Evans A.T. , Peters E. , Shoben A.B. , Meilleur L.R. , Klein E.G. , Tompkins M.K. , Tusler M. .
Source: Psychology & Health, 2017-04-07 00:00:00.0; , p. 1-22.
EPub date: 2017-04-07 00:00:00.0.
PMID: 28385093
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A Growing Geographic Disparity: Rural And Urban Cigarette Smoking Trends In The United States
Authors: Doogan N.J. , Roberts M.E. , Wewers M.E. , Stanton C.A. , Keith D.R. , Gaalema D.E. , Kurti A.N. , Redner R. , Cepeda-Benito A. , Bunn J.Y. , et al. .
Source: Preventive Medicine, 2017-03-15 00:00:00.0; , .
PMID: 28315761
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The Impact Of A Federal Cigarette Minimum Pack Price Policy On Cigarette Use In The Usa
Authors: Doogan N.J. , Wewers M.E. , Berman M. .
Source: Tobacco Control, 2017-03-04 00:00:00.0; , .
PMID: 28259846
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Icons For Health Effects Of Cigarette Smoke: A Test Of Semiotic Type
Authors: Lazard A.J. , Schmidt A. , Vu H. , Byron M.J. , Peters E. , Boynton M.H. , Brewer N.T. .
Source: Journal Of Behavioral Medicine, 2017-02-20 00:00:00.0; , .
PMID: 28220342
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Metabolomic profiles of current cigarette smokers.
Authors: Hsu P.C. , Lan R.S. , Brasky T.M. , Marian C. , Cheema A.K. , Ressom H.W. , Loffredo C.A. , Pickworth W.B. , Shields P.G. .
Source: Molecular Carcinogenesis, 2017 Feb; 56(2), p. 594-606.
EPub date: 2016-08-22 00:00:00.0.
PMID: 27341184
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Health Warning Labels for Smokeless Tobacco: The Impact of Graphic Images on Attention, Recall, and Craving.
Authors: Klein E.G. , Quisenberry A.J. , Shoben A.B. , Cooper S. , Ferketich A.K. , Berman M. , Peters E. , Wewers M.E. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2017-01-28 00:00:00.0; , .
EPub date: 2017-01-28 00:00:00.0.
PMID: 28339596
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A Descriptive Report of Electronic Cigarette Use After Participation in a Community-Based Tobacco Cessation Trial.
Authors: Curry E. , Nemeth J.M. , Wermert A. , Conroy S. , Shoben A. , Ferketich A.K. , Wewers M.E. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2017-01-21 00:00:00.0; , .
EPub date: 2017-01-21 00:00:00.0.
PMID: 28339576
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Menthol Smokers: Metabolomic Profiling And Smoking Behavior
Authors: Hsu P.C. , Lan R.S. , Brasky T.M. , Marian C. , Cheema A.K. , Ressom H.W. , Loffredo C.A. , Pickworth W.B. , Shields P.G. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2017 Jan; 26(1), p. 51-60.
PMID: 27628308
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Communicating Tobacco Product Information to the Public.
Authors: Berman M.L. , Byron M.J. , Hemmerich N. , Lindblom E.N. , Lazard A.J. , Peters E. , Brewer N.T. .
Source: Food And Drug Law Journal, 2017; 72(3), p. 386-405.
PMID: 29398886
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Cigarette Graphic Warning Labels Are Not Created Equal: They Can Increase or Decrease Smokers' Quit Intentions Relative to Text-only Warnings.
Authors: Evans A.T. , Peters E. , Shoben A. , Meilleur L. , Klein E.G. , Tompkins M.K. , Romer D. , Tusler M. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2016-12-28 00:00:00.0; , .
EPub date: 2016-12-28 00:00:00.0.
PMID: 28031378
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Co-occurring risk factors for current cigarette smoking in a U.S. nationally representative sample.
Authors: Higgins S.T. , Kurti A.N. , Redner R. , White T.J. , Keith D.R. , Gaalema D.E. , Sprague B.L. , Stanton C.A. , Roberts M.E. , Doogan N.J. , et al. .
Source: Preventive Medicine, 2016 Nov; 92, p. 110-117.
PMID: 26902875
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Trends in tobacco use among US adults with chronic health conditions: National Survey on Drug Use and Health 2005-2013.
Authors: Stanton C.A. , Keith D.R. , Gaalema D.E. , Bunn J.Y. , Doogan N.J. , Redner R. , Kurti A.N. , Roberts M.E. , Higgins S.T. .
Source: Preventive Medicine, 2016 Nov; 92, p. 160-168.
PMID: 27090919
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Persistent Alterations Of Gene Expression Profiling Of Human Peripheral Blood Mononuclear Cells From Smokers
Authors: Weng D.Y. , Chen J. , Taslim C. , Hsu P.C. , Marian C. , David S.P. , Loffredo C.A. , Shields P.G. .
Source: Molecular Carcinogenesis, 2016 Oct; 55(10), p. 1424-37.
PMID: 26294040
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Energy Drink Use Among Ohio Appalachian Smokers
Authors: Davison G. , Shoben A. , Pasch K.E. , Klein E.G. .
Source: Journal Of Community Health, 2016 Oct; 41(5), p. 897-902.
PMID: 26879965
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Eye Tracking Outcomes In Tobacco Control Regulation And Communication: A Systematic Review
Authors: Meernik C. , Jarman K. , Wright S.T. , Klein E.G. , Goldstein A.O. , Ranney L. .
Source: Tobacco Regulatory Science, 2016 Oct; 2(4), p. 377-403.
PMID: 27668270
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Emotion in the Law and the Lab: The Case of Graphic Cigarette Warnings.
Authors: Peters E. , Evans A.T. , Hemmerich N. , Berman M. .
Source: Tobacco Regulatory Science, 2016 Oct; 2(4), p. 404-413.
EPub date: 2016-10-01 00:00:00.0.
PMID: 29057296
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Defining Tobacco Regulatory Science Competencies
Authors: Wipfli H.L. , Berman M. , Hanson K. , Kelder S. , Solis A. , Villanti A.C. , Ribeiro C.M. , Meissner H.I. , Anderson R. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2016-07-14 00:00:00.0; , .
PMID: 27613917
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Online E-cigarette Marketing Claims: A Systematic Content and Legal Analysis.
Authors: Klein E.G. , Berman M. , Hemmerich N. , Carlson C. , Htut S. , Slater M. .
Source: Tobacco Regulatory Science, 2016 Jul; 2(3), p. 252-262.
PMID: 27446984
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Rural tobacco use across the United States: How rural and urban areas differ, broken down by census regions and divisions.
Authors: Roberts M.E. , Doogan N.J. , Kurti A.N. , Redner R. , Gaalema D.E. , Stanton C.A. , White T.J. , Higgins S.T. .
Source: Health & Place, 2016 May; 39, p. 153-9.
PMID: 27107746
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Understanding Tobacco Use Onset Among African Americans.
Authors: Roberts M.E. , Colby S.M. , Lu B. , Ferketich A.K. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2016 Apr; 18 Suppl 1, p. S49-56.
PMID: 26980864
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The Age-related Positivity Effect and Tobacco Warning Labels.
Authors: Roberts M.E. , Peters E. , Ferketich A.K. , Klein E.G. .
Source: Tobacco Regulatory Science, 2016 Apr; 2(2), p. 176-185.
PMID: 27617273
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Chemical and toxicological characteristics of conventional and low-TSNA moist snuff tobacco products.
Authors: Song M.A. , Marian C. , Brasky T.M. , Reisinger S. , Djordjevic M. , Shields P.G. .
Source: Toxicology Letters, 2016-03-14 00:00:00.0; 245, p. 68-77.
EPub date: 2016-03-14 00:00:00.0.
PMID: 26802282
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