Skip to main content
An official website of the United States government
Grant Details

Grant Number: 5R21CA202013-03 Interpret this number
Primary Investigator: Zoellner, Jamie
Organization: University Of Virginia
Project Title: Sipsmarter Southwest Virginia: a Systems-Based Approach to Disseminate Andimplement an Effective Sugar-Sweetened Beverage Reduction Intervention
Fiscal Year: 2017


Abstract

 DESCRIPTION (provided by applicant): The slow translation of health-related research findings into practice is well documented and this extends to health literacy interventions. Our R21 application is driven by the desire to reduce the excessive lag time along the research pipeline by speeding the translation of emergent findings from SIPsmartER, a health literacy intervention to reduce sugar-sweetened beverage (SSB) consumption. SSB consumption is a high priority public health behavior and contributes ~7% of total energy intake for US adults. Unfortunately, the targeted Appalachian region of Southwest Virginia for this application exceeds the national average consumption of SSB by more than three times. SIPsmartER is a theory-based, 6-month, multi-component health literacy intervention designed to reduce SSB intake and is currently being tested in a type 1 effectiveness- implementation hybrid randomized-controlled trial. Emerging findings from this rigorously designed trial illustrate that SIPsmartER is an efficacious intervention to decrease SSB intake: intervention participants have significantly decreased SSB intake by 227 SSB kcals/day (95% CI=326, 127; p<0.001) from 0 to 6 months compared to a decrease of 53 SSB kcals/day (95% CI=326, 127; p<0.001) in the control group (p<0.001). Furthermore, SSB outcomes and SIPsmartER completion rates do not vary by health literacy status and preliminary data indicate that SSB reductions are being sustained one year post intervention. To translate these promising effects into population-level SSB reductions, a concerted effort is needed to understand the feasibility of organizational-level adoption and implementation of SIPsmartER within existing systems and to develop an implementation support system to aid in delivery. Additionally, since a system-delivered SIPsmartER intervention would be conducted under less-controlled conditions, ascertaining individual-level effects on SSB is necessary. Thus, our approach is guided by the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) Framework and integrates the Interactive Systems Framework and cutting- edge strategies for advancing organizational-level health literacy. We target four medically-underserved Southwest Virginia Department of Health districts and their client population, and propose a mixed-methods design that includes formative, process, and outcome evaluations. Our primary aim is to develop, establish feasibility, and determine the potential utility of an implementation strategy for SIPsmartER, which will reflect system-level needs and resources specific to SIPsmartER, as well as build general capacity related to organizational health literacy. Secondary aims are to determine the adoption and implementation process at the organization-level and determine individual-level reach and effectiveness of SIPsmartER within an existing system. The goal is to have a SIPsmartER implementation support system that can be tested in a subsequent R01 type 3 effectiveness-implementation hybrid randomized-controlled trial, with a long-term goal of broad scale SIPsmartER dissemination within public health systems to achieve population-level SSB reductions.



Publications

Potential Theranostic Roles of SLC4 Molecules in Human Diseases.
Authors: Zhong J. , Dong J. , Ruan W. , Duan X. .
Source: International journal of molecular sciences, 2023-10-13; 24(20), .
EPub date: 2023-10-13.
PMID: 37894847
Related Citations

Crosstalk between stomatology and medical genetics: Viewpoints of Chinese scholars.
Authors: Duan X. .
Source: Oral diseases, 2023 Sep; 29(6), p. 2331-2333.
EPub date: 2023-07-24.
PMID: 37485917
Related Citations

Molecular-based phenotype variations in amelogenesis imperfecta.
Authors: Dong J. , Ruan W. , Duan X. .
Source: Oral diseases, 2023 Sep; 29(6), p. 2334-2365.
EPub date: 2023-05-08.
PMID: 37154292
Related Citations

Hereditary dentin defects with systemic diseases.
Authors: Su T. , Zhu Y. , Wang X. , Zhu Q. , Duan X. .
Source: Oral diseases, 2023 Sep; 29(6), p. 2376-2393.
EPub date: 2023-04-24.
PMID: 37094075
Related Citations

[Application status and prospect of genetic counseling in stomatology in China].
Authors: Duan X.H. .
Source: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2023-08-09; 58(8), p. 759-765.
PMID: 37550035
Related Citations

[Expert consensus on the biobank development of oral genetic diseases and rare diseases and storage codes of related biological samples from craniofacial and oral region].
Authors: Ruan W.Y. , Zhang Y.L. , Zheng S.G. , Sun Y. , Fan Z.P. , Song Y.L. , Sun H.C. , Wang W.M. , Dai J.W. , Zhao Z.J. , et al. .
Source: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2023-08-09; 58(8), p. 749-758.
PMID: 37550034
Related Citations

A Novel 90-kbp Deletion of RUNX2 Associated with Cleidocranial Dysplasia.
Authors: Zhang Y. , Duan X. .
Source: Genes, 2022-06-23; 13(7), .
EPub date: 2022-06-23.
PMID: 35885911
Related Citations

Recognition of potential therapeutic role of 2-hydroxy-3-methylanthraquinones in the treatment of gallbladder carcinoma: A proteomics analysis.
Authors: Jin H. , Cui M. .
Source: Fundamental & clinical pharmacology, 2022 Apr; 36(2), p. 350-362.
EPub date: 2021-12-10.
PMID: 34850442
Related Citations

The reach and effectiveness of SIPsmartER when implemented by rural public health departments: a pilot dissemination and implementation trial to reduce sugar-sweetened beverages.
Authors: Zoellner J.M. , Porter K.J. , You W. , Estabrooks P.A. , Perzynski K. , Ray P.A. , Cantrell E.S. .
Source: Translational behavioral medicine, 2020-08-07; 10(3), p. 676-684.
PMID: 30690550
Related Citations

SIPsmartER delivered through rural, local health districts: adoption and implementation outcomes.
Authors: Porter K.J. , Brock D.J. , Estabrooks P.A. , Perzynski K.M. , Hecht E.R. , Ray P. , Kruzliakova N. , Cantrell E.S. , Zoellner J.M. .
Source: BMC public health, 2019-09-18; 19(1), p. 1273.
EPub date: 2019-09-18.
PMID: 31533683
Related Citations




Back to Top