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Grant Details

Grant Number: 5R01CA168647-05 Interpret this number
Primary Investigator: Siminoff, Laura
Organization: Temple Univ Of The Commonwealth
Project Title: Communication and Economic Outcomes for Cancer Survivors
Fiscal Year: 2017


DESCRIPTION (provided by applicant): The goal of this study will be to assess whether cancer communication between patients and their family caregivers is an important and independent factor in specific cancer care outcomes, including economic outcomes, especially labor market participation, quality of life and decisional outcomes. This study focuses on patients with hematological malignancies in adults which are important to study for a number of reasons. These cancers have been steadily increasing in the U.S. with an estimated 137,266 new cases in 2010. In addition, hematological cancer patients' social and psychological challenges and outcomes have not been adequately studied. Hematological cancers are particularly challenging because of their chronicity. How patients survive with this disease, including their ability to maintain their social and family commitments is critical. Few studies, however, have examined how hematologic cancers affect patients' and their caregivers' labor market participation. Strikingly, in comparison to the productivity cost of other cancers, hematological cancers are among the most costly cancers in terms of productivity loss due to premature death. This study will follow 250 pairs of employed hematologic cancer patients and their family caregivers over a two-year period to assess how they communicate about treatment and care decisions, which lead to specific psychosocial, economic, and healthcare outcomes. This study has the following aims: Aim 1. Test longitudinally how cancer communication between caregivers and patients are associated with short and long-term economic, psychosocial, and healthcare outcomes. Aim 2. Examine patient and family characteristics that are associated with decreased levels of cancer communication.


Cancer patient and caregiver communication about economic concerns and the effect on patient and caregiver partners' perceptions of family functioning.
Authors: Thomson M.D. , Wilson-Genderson M. , Siminoff L.A. .
Source: Journal of cancer survivorship : research and practice, 2023-02-20; , .
EPub date: 2023-02-20.
PMID: 36808388
Related Citations

Understanding cancer caregiver burden over time: Dyadic assessments of family cohesion, conflict and communication.
Authors: Thomson M.D. , Genderson M.W. , Siminoff L.A. .
Source: Patient education and counseling, 2022 Jun; 105(6), p. 1545-1551.
EPub date: 2021-10-12.
PMID: 34728096
Related Citations

The presence of a secondary caregiver differentiates primary cancer caregiver well-being.
Authors: Thomson M.D. , Wilson-Genderson M. , Siminoff L.A. .
Source: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022 Feb; 30(2), p. 1597-1605.
EPub date: 2021-09-21.
PMID: 34546455
Related Citations

Hematological cancer patient-caregiver dyadic communication: A longitudinal examination of cancer communication concordance.
Authors: Siminoff L.A. , Wilson-Genderson M. , Barta S. , Thomson M.D. .
Source: Psycho-oncology, 2020 Oct; 29(10), p. 1571-1578.
EPub date: 2020-08-04.
PMID: 32627258
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Managing work and cancer treatment: Experiences among survivors of hematological cancer.
Authors: Thomson M.D. , Siminoff L.A. .
Source: Cancer, 2018-07-01; 124(13), p. 2824-2831.
EPub date: 2018-04-16.
PMID: 29660822
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