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Grant Details

Grant Number: 5R03CA202566-02 Interpret this number
Primary Investigator: Kepka, Deanna
Organization: University Of Utah
Project Title: Community-Level Geographic Factors and HPV Vaccination in the U.S.
Fiscal Year: 2017


 DESCRIPTION (provided by applicant): While individual- and provider-level factors for low Human Papillomavirus (HPV) vaccination rates in the United States (U.S.) have been well examined, the role of community-level geographic factors in HPV vaccine initiation and 3-dose completion in the U.S. is unknown. Geographic and neighborhood factors could influence vaccination through several pathways linked to material resources of the neighborhood, availability and ease of access to health-care facilities and services, social capital (e.g., socia contagion, similar norms of behavior), and residential segregation. Using data from the National Immunization Survey-Teen (NIS-Teen), an annual survey conducted by the Centers for Disease Control and Prevention to monitor vaccination uptake in the U.S., associations between HPV vaccination among adolescent girls and boys and community-level geographic factors including poverty, rural/urban residence, and racial composition will be examined. Zip code and county- level geographic identifiers are not available in the public-use NIS-Teen datasets, and therefore these geographic identifiers will be accessed and linked via the restricted use NIS-Teen files to provide a novel examination of geographic factors' role in HPV vaccination. First, we will identify community-level geographic factors that are independent predictors of both vaccine initiation and series completion, among U.S. teen girls and boys separately. Next, we will investigate how geographic and community level socioeconomic factors impact and interact with individual level factors associated with HPV vaccine initiation and completion. This will be the first study to provide much needed information on the influence of community-level geographic factors on HPV vaccine initiation and completion among a nationally representative sample of adolescents in the U.S. Given the low rates of HPV vaccination in the U.S., the results from the proposed study will help inform public health practice and the development of geographically targeted interventions to improve HPV vaccination in the United States.


A Multi-state Evaluation of Oral Health Students' Knowledge of Human Papillomavirus-Related Oropharyngeal Cancer and HPV Vaccination.
Authors: Rutkoski H. , Tay D.L. , Dixon B.L. , Pinzon L.M. , Mooney R. , Winkler J.R. , Kepka D. .
Source: Journal of cancer education : the official journal of the American Association for Cancer Education, 2020 Oct; 35(5), p. 1017-1025.
PMID: 31222578
Related Citations

HPV Vaccination Coverage Among US Teens Across the Rural-Urban Continuum.
Authors: Swiecki-Sikora A.L. , Henry K.A. , Kepka D. .
Source: The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association, 2019 Sep; 35(4), p. 506-517.
EPub date: 2019-01-31.
PMID: 30703854
Related Citations

White, affluent, educated parents are least likely to choose HPV vaccination for their children: a cross-sectional study of the National Immunization Study - teen.
Authors: Warner E.L. , Ding Q. , Pappas L.M. , Henry K. , Kepka D. .
Source: BMC pediatrics, 2017-12-01; 17(1), p. 200.
EPub date: 2017-12-01.
PMID: 29191180
Related Citations

Area-based socioeconomic factors and Human Papillomavirus (HPV) vaccination among teen boys in the United States.
Authors: Henry K.A. , Swiecki-Sikora A.L. , Stroup A.M. , Warner E.L. , Kepka D. .
Source: BMC public health, 2017-07-14; 18(1), p. 19.
EPub date: 2017-07-14.
PMID: 28709420
Related Citations

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