Grant Number:	1R01CA194178-01A1 Interpret this number
Primary Investigator:	Davey, Maureen
Organization:	Drexel University
Project Title:	African American Families Fighting Parental Cancer Together
Fiscal Year:	2016

 DESCRIPTION (provided by applicant): In 2015, an estimated 340,000 parents of school age children will be newly diagnosed with cancer in the U.S. Parental cancer causes significant emotional distress in both diagnosed parents and children. African American (AA) adults experience a disproportionate burden of solid tumor cancers (e.g., breast, prostate, lung, and colon) which puts AA adolescents, a vulnerable population to begin with, at high risk for parental cancer related distress. Treatments have been somewhat successful for younger school age children (ages 7-12) of cancer patients but most treatment studies have included white middle class samples. Differences in attitudes, daily functioning and levels of distress among different ethnic and racial groups are well-documented, yet few culturally sensitive family intervention programs have been developed for AA families coping with cancer. Building on the PI's previous studies with AA families coping with parental cancer, we propose to conduct a randomized control trial to address this gap. We will of a culturally sensitive family-based intervention that targets the parent child relationship in AA families coping with the impact of solid tumor parental cancer. We will randomize 172 AA families coping with parental cancer to either Families Fighting Cancer Together (FFCT) or to parent psycho-education (TAU). Both manualized treatments include 5 bi-monthly sessions over 10 weeks. Subjects will be African American parents diagnosed for the first time in the past 12 months with Stage I, II, or III solid tumor cancers with at least one child between the ages of 12 and 18 living at home. Patients will be recruited from 3 large inner city cancer centers where there is an estimated 500 eligible low to middle income AA cancer patients a year. Family assessments will be done at baseline, post-treatment (10 weeks), 6-month, and 12-month follow-up. The proposed R01 research has the following aims: Aim 1: Compare the efficacy of FFCT to TAU in reducing depressive symptoms (CDI) and anxiety (RCMAS) in AA adolescents at post-treatment and long term outcome (6 and 12-month follow-up). Aim 2: Compare the efficacy of FFCT to TAU in reducing parental stress (PCQ: impact of illness on child/concerns about parenting) in AA parents at post-treatment and long term outcome (6 and 12-month follow-up). Exploratory Aims: 1. Explore whether moderators identified in Caucasian samples have a similar impact on treatment in AA samples. Specifically, we will examine: a) perceived level of group support, b) gender and age of adolescent, c) parent's marital status, d) SES, and e) stage of parent's cancer on the impact of treatment. 2. Explore whether changes in parent-child attachment and communication mediate the association between treatment and depressive symptoms (CDI) and anxiety (RCMAS) at 6 and12-month follow-up. Treatments to help adolescents cope with the impact of parental cancer are urgently needed, particularly those designed to reach low-income AA populations. Developing effective and transportable family-based interventions for this population could improve developmental adjustment to this significant life stressor at a critical point in the livesof adolescents.




Person-Centred Care: A Support Strategy for Managing Non-Communicable Diseases.
Authors: Lorber M. , Reljić N.M. , Kegl B. , Fekonja Z. , Štiglic G. , Davey A. , Kmetec S. .
Source: Healthcare (basel, Switzerland), 2024-02-23 00:00:00.0; 12(5), .
EPub date: 2024-02-23 00:00:00.0.
PMID: 38470637
Related Citations

Cancer and the family: Variations by sex and race/ethnicity.
Authors: Asiedu C. , McKinney N.S. , Willis A.I. , Lewis F.M. , Virtue S. , Davey A. .
Source: Cancer Medicine, 2024 Jan; 13(2), p. e6969.
PMID: 38379329
Related Citations

Frailty in community-dwelling older people and nursing home residents: An adaptation and validation study.
Authors: Kmetec S. , Fekonja Z. , Davey A. , Kegl B. , Mori J. , Reljić N.M. , McCormack B. , Lorber M. .
Source: Journal Of Advanced Nursing, 2023-10-12 00:00:00.0; , .
EPub date: 2023-10-12 00:00:00.0.
PMID: 37828685
Related Citations

Associations between Sleep Quality, Frailty, and Quality of Life among Older Adults in Community and Nursing Home Settings.
Authors: Lorber M. , Kmetec S. , Davey A. , Mlinar Reljić N. , Fekonja Z. , Kegl B. .
Source: International Journal Of Environmental Research And Public Health, 2023-03-10 00:00:00.0; 20(6), .
EPub date: 2023-03-10 00:00:00.0.
PMID: 36981847
Related Citations

Development of a slovenian version of the pittsburgh sleep quality index (PSQI-SLO) for use with older adults.
Authors: Kmetec S. , Fekonja Z. , Davey A. , Mlinar Reljić N. , Lorber M. .
Source: International Journal Of Older People Nursing, 2021-08-09 00:00:00.0; , p. e12411.
EPub date: 2021-08-09 00:00:00.0.
PMID: 34370894
Related Citations

Sleep Duration and Sleep Quality Associated with Better Functional Exercise Capacity in African-American Smokers at Risk for COPD.
Authors: Gangemi A.J. , Satti A. , Zantah M. , Blair R. , Brewer B. , Ma G. , Grandner M.A. , Davey A. , Criner G.J. , Patterson F. .
Source: Chest, 2020-04-22 00:00:00.0; , .
EPub date: 2020-04-22 00:00:00.0.
PMID: 32333930
Related Citations

Breakfast in the Classroom Initiative and Students' Breakfast Consumption Behaviors: A Group Randomized Trial.
Authors: Bauer K.W. , Foster G.D. , Weeks H.M. , Polonsky H.M. , Davey A. , Sherman S. , Abel M.L. , Ruth K.J. , Dale L.C. , Fisher J.O. .
Source: American Journal Of Public Health, 2020 04; 110(4), p. 540-546.
EPub date: 2020-02-20 00:00:00.0.
PMID: 32078356
Related Citations

Carotid Artery Blood Flow Velocities and Cognitive Performance: Forecasting Cognitive Decline.
Authors: Elias M.F. , Torres R.V. , Davey A. .
Source: American Journal Of Hypertension, 2019-02-12 00:00:00.0; 32(3), p. 237-239.
PMID: 30535136
Related Citations

Physical Performance and Fall Risk in Persons With Traumatic Brain Injury.
Authors: Klima D. , Morgan L. , Baylor M. , Reilly C. , Gladmon D. , Davey A. .
Source: Perceptual And Motor Skills, 2019 Feb; 126(1), p. 50-69.
EPub date: 2018-11-20 00:00:00.0.
PMID: 30458668
Related Citations

Does sleep duration, napping, and social jetlag predict hemoglobin A1c among college students with type 1 diabetes mellitus?
Authors: Saylor J. , Ji X. , Calamaro C.J. , Davey A. .
Source: Diabetes Research And Clinical Practice, 2019 Feb; 148, p. 102-109.
EPub date: 2019-01-11 00:00:00.0.
PMID: 30641174
Related Citations

Clinico-Neuropathological Findings in the Oldest Old from the Georgia Centenarian Study.
Authors: Tanprasertsuk J. , Johnson E.J. , Johnson M.A. , Poon L.W. , Nelson P.T. , Davey A. , Martin P. , Barbey A.K. , Barger K. , Wang X.D. , et al. .
Source: Journal Of Alzheimer's Disease : Jad, 2019; 70(1), p. 35-49.
PMID: 31177211
Related Citations

Study protocol: a randomized control trial of African American families fighting parental cancer together.
Authors: McKinney N.S. , Virtue S. , Lewis F.M. , Willis A.I. , Pettyjohn T. , Harmon L.R. , Davey A. .
Source: Bmc Cancer, 2018-11-20 00:00:00.0; 18(1), p. 1140.
EPub date: 2018-11-20 00:00:00.0.
PMID: 30453906
Related Citations

Diastolic Blood Pressure, Not Just Systolic Blood Pressure, Is Related to Cerebral Measures in Middle Age: Implications for Prospective Studies.
Authors: Elias M.F. , Torres R.V. , Davey A. .
Source: American Journal Of Hypertension, 2018-11-13 00:00:00.0; 31(12), p. 1263-1265.
PMID: 30113618
Related Citations

Clinical Trials of Blood Pressure Lowering and Antihypertensive Medication: Is Cognitive Measurement State-of-the-Art?
Authors: Elias M.F. , Torres R.V. , Davey A. .
Source: American Journal Of Hypertension, 2018-05-07 00:00:00.0; 31(6), p. 631-642.
PMID: 29481592
Related Citations

Parameters of Left Ventricular Mass and Dementia: Moving the Literature Forward.
Authors: Elias M.F. , Torres R.V. , Davey A. .
Source: Hypertension (dallas, Tex. : 1979), 2018 03; 71(3), p. 411-412.
EPub date: 2018-01-29 00:00:00.0.
PMID: 29378855
Related Citations

Breakfast Quality Varies by Location among Low-Income Ethnically Diverse Children in Public Urban Schools.
Authors: Polonsky H.M. , Davey A. , Bauer K.W. , Foster G.D. , Sherman S. , Abel M.L. , Dale L.C. , Fisher J.O. .
Source: Journal Of Nutrition Education And Behavior, 2018 02; 50(2), p. 190-197.e1.
EPub date: 2017-11-06 00:00:00.0.
PMID: 29107474
Related Citations

Systolic orthostatic hypotension is related to lowered cognitive function: Findings from the Maine-Syracuse Longitudinal Study.
Authors: Torres R.V. , Elias M.F. , Crichton G.E. , Dore G.A. , Davey A. .
Source: Journal Of Clinical Hypertension (greenwich, Conn.), 2017 Dec; 19(12), p. 1357-1365.
EPub date: 2017-09-19 00:00:00.0.
PMID: 28929576
Related Citations

Intensive Blood Pressure Control Improves Cognitive Performance: Pushing the Envelope cum Judicia.
Authors: Elias M.F. , Torres R. , Davey A. .
Source: American Journal Of Hypertension, 2017-06-01 00:00:00.0; 30(6), p. 556-558.
PMID: 28402387
Related Citations