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Grant Details

Grant Number: 5R01CA166785-05 Interpret this number
Primary Investigator: Hobbs, Joseph
Organization: Augusta University
Project Title: Efficacy-to-Effectiveness Transition of an Educational Program to Increase Colore
Fiscal Year: 2016
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Abstract

DESCRIPTION (provided by applicant): African Americans have the highest incidence and mortality and are less likely than whites to have screening for colorectal cancer (CRC). We recently completed a five-year randomized controlled community intervention trial that demonstrated the efficacy of a small group education intervention (now named EPICS or Educational Program to Increase Colorectal Cancer Screening) that doubled the CRC screening rate compared to the control group rate. EPICS was then put into practice in partnership with the local health department and was equally effective. We are now disseminating the intervention across the state of Georgia. In this application we propose a national dissemination and implementation study. We propose using Rogers' Diffusion of Innovation Theory and Glasgow's RE-AIM (Reach, Effectiveness, Adoption, Implementation, Maintenance) evaluation framework to pursue the following specific aims: 1) test passive and active approaches to disseminating EPICS to increase screening rates for colorectal cancer among African Americans; 2) measure the extent to which EPICS is accepted by community coalitions and the fidelity of implementation in various settings and 3) estimate the potential translatability and public health impact of EPICS. Diffusion of Innovations Theory will guide the process of EPICS dissemination and RE-AIM will be used to assess this dissemination and its impact. For this study we propose a cluster randomized controlled trial of 20 community coalitions from across the United States, assigned to one of four conditions: (1, passive) web-based access to facilitator training materials and toolkits without technical assistance (TA); (2, passive) the sam as 1, but with TA; (3, active) in-person access (IP) to facilitator training materials and toolkits without TA and (4, active) IP access to facilitator training materials and toolkits with TA. Each community coalition will partner with three settings for implementation: a church, clinic and community site. African Americans, 50-74 years of age, who are not current on CRC screening are eligible for study participation (n=7,200 or n=360 eligible individuals per community coalition). This assumes a sample size of 1800 per study arm, a significance level of 5% (i.e. alpha = 0.05), and a two-sided two-group chi-square test of proportions. Assuming that we observe in our study an increase in screening rates of colorectal cancer among participants in active arms compared to screening rates among participants in the passive arms, we will have greater than 99% power to detect statistically significant differences in the proportions. All statistical tests proposed for this study will be two-sided and will be performed using a significance level of 5% (i.e., alpha=0.05).

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Publications

Patient-Centered Medical Home Status and Preparedness to Assess Resident Milestones: A CERA Study.
Authors: Wilkins T. , Yoo W. , Gillies R.A. , Dahl-Smith J. , Dubose J. , Hobbs J. , Smith S. , Seehusen D.A. .
Source: Primer (leawood), 2018 May; 2, .
PMID: 29782601
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Health-related quality of life of African-American female breast cancer survivors, survivors of other cancers, and those without cancer.
Authors: Claridy M.D. , Ansa B. , Damus F. , Alema-Mensah E. , Smith S.A. .
Source: Quality Of Life Research : An International Journal Of Quality Of Life Aspects Of Treatment, Care And Rehabilitation, 2018-04-27 00:00:00.0; , .
EPub date: 2018-04-27 00:00:00.0.
PMID: 29704078
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Evaluation of Colorectal Cancer Incidence Trends in the United States (2000-2014).
Authors: Ansa B.E. , Coughlin S.S. , Alema-Mensah E. , Smith S.A. .
Source: Journal Of Clinical Medicine, 2018-01-30 00:00:00.0; 7(2), .
EPub date: 2018-01-30 00:00:00.0.
PMID: 29385768
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Patterns of Internet-based health information seeking in adult survivors of childhood cancer.
Authors: Claridy M.D. , Hudson M.M. , Caplan L. , Mitby P.A. , Leisenring W. , Smith S.A. , Robison L.L. , Mertens A.C. .
Source: Pediatric Blood & Cancer, 2018-01-19 00:00:00.0; , .
EPub date: 2018-01-19 00:00:00.0.
PMID: 29350454
Related Citations

Social networks as predictors of colorectal cancer screening in African Americans.
Authors: Alema-Mensah E. , Smith S.A. , Claridy M. , Ede V. , Ansa B. , Blumenthal D.S. .
Source: Journal Of The Georgia Public Health Association, 2017 Winter; 6(3), p. 369-372.
PMID: 28730185
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Community engagement to address socio-ecological barriers to physical activity among African American breast cancer survivors.
Authors: Smith S.A. , Whitehead M.S. , Sheats J.Q. , Chubb B. , Alema-Mensah E. , Ansa B.E. .
Source: Journal Of The Georgia Public Health Association, 2017 Winter; 6(3), p. 393-397.
PMID: 28736768
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Racial and ethnic disparities in smoking prevalence in Israel and the United States: progress to date and prospects for the future.
Authors: Blumenthal D.S. .
Source: Israel Journal Of Health Policy Research, 2017-10-02 00:00:00.0; 6(1), p. 51.
EPub date: 2017-10-02 00:00:00.0.
PMID: 28969689
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Community-Based Participatory Research to Promote Healthy Diet and Nutrition and Prevent and Control Obesity Among African-Americans: a Literature Review.
Authors: Coughlin S.S. , Smith S.A. .
Source: Journal Of Racial And Ethnic Health Disparities, 2017 Apr; 4(2), p. 259-268.
PMID: 27059053
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TEACH Kitchen: A Chronological Review of Accomplishments.
Authors: Chae J.H. , Ansa B.E. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2017 Spring; 6(4), p. 444-455.
PMID: 28890945
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Persons Who Failed to Obtain Colorectal Cancer Screening Despite Participation in an Evidence-Based Intervention.
Authors: Smith S.A. , Alema-Mensah E. , Yoo W. , Ansa B.E. , Blumenthal D.S. .
Source: Journal Of Community Health, 2017 Feb; 42(1), p. 30-34.
PMID: 27395048
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Patient perspectives of an individualized diabetes care management plan.
Authors: Saucier A.N. , Ansa B. , Coffin J. , Akhtar M. , Miller A. , Mahoney H. , Hodo D.M. , Duffie C. , Fontenot B. , Andrews H.E. , et al. .
Source: European Journal For Person Centered Healthcare, 2017; 5(2), p. 213-219.
PMID: 28835847
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Application of a faith-based integration tool to assess mental and physical health interventions.
Authors: Saunders D.M. , Leak J. , Carver M.E. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2017; 7(1), p. 26-38.
PMID: 29354795
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Factors associated with body mass index among African American breast cancer survivors.
Authors: Smith S.A. , Claridy M.D. , Whitehead M.S. , Sheats J.Q. , Yoo W. , Alema-Mensah E. , Ansa B.E. , Braithwaite R.L. .
Source: Journal Of The Georgia Public Health Association, 2016 Winter; 5(3), p. 259-265.
PMID: 27019873
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A review of community-based participatory research studies to promote physical activity among African Americans.
Authors: Coughlin S.S. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2016 Winter; 5(3), p. 220-227.
PMID: 27034993
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Toward the Elimination of Colorectal Cancer Disparities Among African Americans.
Authors: Coughlin S.S. , Blumenthal D.S. , Seay S.J. , Smith S.A. .
Source: Journal Of Racial And Ethnic Health Disparities, 2016 Dec; 3(4), p. 555-564.
PMID: 27294749
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Determinants Of Adherence To Physical Activity Guidelines Among Overweight And Obese African American Breast Cancer Survivors: Implications For An Intervention Approach
Authors: Smith S.A. , Ansa B.E. , Yoo W. , Whitehead M.S. , Coughlin S.S. .
Source: Ethnicity & Health, 2016-11-14 00:00:00.0; , p. 1-13.
PMID: 27838922
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Trends In Hiv Testing Among Adults In Georgia: Analysis Of The 2011-2015 Brfss Data
Authors: Ansa B.E. , White S. , Chung Y. , Smith S.A. .
Source: International Journal Of Environmental Research And Public Health, 2016-11-11 00:00:00.0; 13(11), .
PMID: 27845740
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Reducing Disparities By Way Of A Cancer Disparities Research Training Program
Authors: Caplan L.S. , Akintobi T.H. , Gordon T.K. , Zellner T. , Smith S.A. , Blumenthal D.S. .
Source: Journal Of Health Disparities Research And Practice, 2016 Fall; 9(3), p. 103-114.
PMID: 27722034
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How Can We Promote Mentored Student Research In Georgia?
Authors: Webb N.C. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2016 Fall; 6(2 Suppl), p. 180-183.
PMID: 28035347
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Exploration Of Barriers And Facilitators To Publishing Local Public Health Findings: A Mixed Methods Protocol
Authors: Smith S.A. , Webb N.C. , Blumenthal D.S. , Willcox B. , Ballance D. , Kinard F. , Gates M.L. .
Source: Journal Of The Georgia Public Health Association, 2016 Fall; 6(2), p. 169-174.
PMID: 28042615
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Determinants Of Adherence To Nutrition-related Cancer Prevention Guidelines Among African American Breast Cancer Survivors
Authors: Ramirez L.A. , Chung Y. , Wonsuk Y. , Fontenot B. , Ansa B.E. , Whitehead M.S. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2016 Fall; 6(2 Suppl), p. 210-222.
PMID: 28066830
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Engaging African Americans in developing an intervention to reduce breast cancer recurrence: A brief report.
Authors: Smith S.A. , Whitehead M.S. , Sheats J.Q. , Fontenot B. , Alema-Mensah E. , Ansa B. .
Source: Journal Of The Georgia Public Health Association, 2016 Summer; 6(1), p. 76-79.
PMID: 27563692
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Formative research to develop a lifestyle application (app) for African American breast cancer survivors.
Authors: Smith S.A. , Whitehead M.S. , Sheats J.Q. , Fontenot B. , Alema-Mensah E. , Ansa B. .
Source: Journal Of The Georgia Public Health Association, 2016 Summer; 6(1), p. 50-59.
PMID: 27583307
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A systematic review of lifestyle interventions for chronic diseases in rural communities.
Authors: Smith S.A. , Ansa B. .
Source: Journal Of The Georgia Public Health Association, 2016 Spring; 5(4), p. 304-313.
PMID: 27376159
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A Community-engaged Approach To Developing A Mobile Cancer Prevention App: The Mcpa Study Protocol
Authors: Smith S.A. , Whitehead M.S. , Sheats J. , Mastromonico J. , Yoo W. , Coughlin S.S. .
Source: Jmir Research Protocols, 2016-03-02 00:00:00.0; 5(1), p. e34.
PMID: 26935995
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Correlates of Mandrax use and condom beliefs in preventing sexually transmitted infections among a cohort of South African prison inmates.
Authors: Stephens T.T. , Gardner D. , Jones K. , Sifunda S. , Braithwaite R. , Smith S.E. .
Source: International Health, 2016 Mar; 8(2), p. 142-7.
PMID: 26316220
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Correlates of African American female adolescent offenders 3, 4-Methylenedioxymethamphetamine (MDMA or "Ecstasy") use and sexually transmitted infection morbidity.
Authors: Stephens T. , Holliday R.C. , Hopkins S. , Rose S. , Braithwaite R. , Smith S. .
Source: Journal Of Human Behavior In The Social Environment, 2016; 26(2), p. 194-201.
PMID: 26834451
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A Review of Smartphone Applications for Promoting Physical Activity.
Authors: Coughlin S.S. , Whitehead M. , Sheats J.Q. , Mastromonico J. , Smith S. .
Source: Jacobs Journal Of Community Medicine, 2016; 2(1), .
PMID: 27034992
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Age, Race and Regional Disparities in Colorectal Cancer Incidence Rates in Georgia between 2000 and 2012.
Authors: Yoo W. , De S. , Wilkins T. , Smith S.A. , Blumenthal D. .
Source: Annals Of Public Health And Research, 2016; 3(2), .
PMID: 27042701
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Introduction to Public Health and Incarceration: Social Justice Matters.
Authors: Smith S.A. , Braithwaite R.L. .
Source: Journal Of Health Care For The Poor And Underserved, 2016; 27(2A), p. 1-4.
PMID: 27133507
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Ethical and Social Issues in Health Research Involving Incarcerated People.
Authors: Coughlin S.S. , Lewis S.R. , Smith S.A. .
Source: Journal Of Health Care For The Poor And Underserved, 2016; 27(2A), p. 18-28.
PMID: 27133509
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Substance Use Correlates of Depression among African American Male Inmates.
Authors: Holliday R.C. , Braithwaite R.L. , Yancey E. , Akintobi T. , Stevens-Watkins D. , Smith S. , Powell C.L. .
Source: Journal Of Health Care For The Poor And Underserved, 2016; 27(2A), p. 181-93.
PMID: 27133518
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The Eating And Cooking Healthy (teach) Kitchen: A Research Protocol
Authors: White S. , Alva-Ruiz R. , Chen L. , Conger J. , Kuang C. , Murphy C. , Okashah N. , Ollila E. , Smith S.A. , Ansa B.E. .
Source: Journal Of The Georgia Public Health Association, 2016; 6(2), p. 331-336.
PMID: 28066831
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Beliefs and Behaviors about Breast Cancer Recurrence Risk Reduction among African American Breast Cancer Survivors.
Authors: Ansa B. , Yoo W. , Whitehead M. , Coughlin S. , Smith S. .
Source: International Journal Of Environmental Research And Public Health, 2015-12-23 00:00:00.0; 13(1), p. ijerph13010046.
EPub date: 2015-12-23 00:00:00.0.
PMID: 26703650
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Attitudes Toward Breast Cancer Genetic Testing in Five Special Population Groups.
Authors: Ramirez A.G. , Chalela P. , Gallion K.J. , Muñoz E. , Holden A.E. , Burhansstipanov L. , Smith S.A. , Wong-Kim E. , Wyatt S.W. , Suarez L. .
Source: Journal Of Health Disparities Research And Practice, 2015 Fall; 8(4), p. 124-135.
PMID: 26855846
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Advancing breast cancer survivorship among African-American women.
Authors: Coughlin S.S. , Yoo W. , Whitehead M.S. , Smith S.A. .
Source: Breast Cancer Research And Treatment, 2015 Sep; 153(2), p. 253-61.
PMID: 26303657
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Lifestyle Modification Experiences Of African American Breast Cancer Survivors: A Needs Assessment
Authors: Smith S.A. , Claridy M.D. , Smith Whitehead M. , Sheats J.Q. , Yoo W. , Alema-Mensah E.A. , Ansa B.E. , Coughlin S.S. .
Source: Jmir Cancer, 2015-08-17 00:00:00.0; 1(2), p. e9.
PMID: 28410162
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Lifestyle Modification Experiences of African American Breast Cancer Survivors: A Needs Assessment.
Authors: Smith S.A. , Claridy M.D. , Whitehead M.S. , Sheats J.Q. , Yoo W. , Alema-Mensah E.A. , Ansa B.E. , Coughlin S.S. .
Source: Jmir Cancer, 2015 Jul-Dec; 1(2), .
PMID: 26380378
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Community-based participatory research principles for the African American community.
Authors: Smith S.A. , Whitehead M.S. , Sheats J.Q. , Ansa B.E. , Coughlin S.S. , Blumenthal D.S. .
Source: Journal Of The Georgia Public Health Association, 2015 Summer; 5(1), p. 52-56.
PMID: 26336653
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Trends in cancer incidence rates in Georgia, 1982-2011.
Authors: Yoo W. , Coughlin S.S. , Lillard J.W. .
Source: Journal Of The Georgia Public Health Association, 2015 Summer; 5(1), p. 96-100.
PMID: 26336654
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Legislative smoking bans for reducing exposure to secondhand smoke and smoking prevalence: Opportunities for Georgians.
Authors: Coughlin S.S. , Anderson J. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2015 Summer; 5(1), p. 2-7.
PMID: 26345719
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86(th) Annual Georgia Public Health Association Meeting & Conference Report.
Authors: Smith S.A. , Abbott R. , Sims C. .
Source: Journal Of The Georgia Public Health Association, 2015 Summer; 5(1), p. 11-15.
PMID: 26835519
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The Insulin-like Growth Factor Axis, Adipokines, Physical Activity, and Obesity in Relation to Breast Cancer Incidence and Recurrence.
Authors: Coughlin S.S. , Smith S.A. .
Source: Cancer And Clinical Oncology, 2015; 4(2), p. 24-31.
PMID: 26251693
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Evaluation Of Genetic Risk Scores For Prediction Of Dichotomous Outcomes
Authors: Yoo W. , Smith S.A. , Coughlin S.S. .
Source: International Journal Of Molecular Epidemiology And Genetics, 2015; 6(1), p. 1-8.
PMID: 26417399
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The Impact of the Natural, Social, Built, and Policy Environments on Breast Cancer.
Authors: Coughlin S.S. , Smith S.A. .
Source: Journal Of Environment And Health Sciences, 2015; 1(3), .
PMID: 26457327
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Developing a Cookbook with Lifestyle Tips: A Community-Engaged Approach to Promoting Diet-Related Cancer Prevention Guidelines.
Authors: Smith S.A. , Sheats J.Q. , Whitehead M.S. , Delmoor E. , Britt T. , Harris C.L. , Robinson-Flint J. , Porche-Smith L.M. , Umeakunne K.E. , Coughlin S.S. .
Source: Jacobs Journal Of Food And Nutrition, 2015; 2(2), .
PMID: 26709388
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Smartphone Applications for Promoting Healthy Diet and Nutrition: A Literature Review.
Authors: Coughlin S.S. , Whitehead M. , Sheats J.Q. , Mastromonico J. , Hardy D. , Smith S.A. .
Source: Jacobs Journal Of Food And Nutrition, 2015; 2(3), p. 021.
PMID: 26819969
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Promoting colorectal cancer screening among Haitian Americans.
Authors: Coughlin S.S. , Lubetkin E.I. , Hay J.L. , Raphael R. , Smith S.A. .
Source: Journal Of The Georgia Public Health Association, 2015; 5(2), p. 149-152.
PMID: 26819972
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Efficacy to effectiveness transition of an Educational Program to Increase Colorectal Cancer Screening (EPICS): study protocol of a cluster randomized controlled trial.
Authors: Smith S.A. , Blumenthal D.S. .
Source: Implementation Science : Is, 2013-08-07 00:00:00.0; 8, p. 86.
EPub date: 2013-08-07 00:00:00.0.
PMID: 23924263
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Community health workers support community-based participatory research ethics: lessons learned along the research-to-practice-to-community continuum.
Authors: Smith S.A. , Blumenthal D.S. .
Source: Journal Of Health Care For The Poor And Underserved, 2012 Nov; 23(4 Suppl), p. 77-87.
PMID: 23124502
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