Skip to main content
Grant Details

Grant Number: 5R21CA180831-02 Interpret this number
Primary Investigator: Costas, Rosario
Organization: Sloan-Kettering Inst Can Research
Project Title: Cultural Adaptation of Imcp for Latino Patients with Advanced Cancer
Fiscal Year: 2015


DESCRIPTION (provided by applicant): Latinos are at higher risk of poorer psychological and quality of life outcomes when compared to non-Hispanic white patients and other minority patients and commonly report using spiritual and religious strategies to cope with cancer. Maintaining hope, spiritual well-being and finding meaning in the cancer experience is critical for the adjustment and well-being of advanced cancer patients. However, there are no targeted psychosocial or psychotherapeutic interventions available for Latino patients diagnosed with advanced cancer. Individual Meaning-Centered psychotherapy (IMCP) is a novel psychotherapeutic intervention designed to help patients with advanced cancer sustain or enhance a sense of meaning, peace and purpose as they approach the end- of-life. Preliminary findings from the pilot randomized controlled trial demonstrate both the IMCP significantly reduce psychological distress and significantly increase spiritual well-being and a sense of meaning and purpose in life in predominantly non-Hispanic white advanced cancer patients. The long term goal of this study is to linguistically and culturally adapt IMCP for Spanish-speaking Latino cancer patients. The overall objective of this study is to use a mixed-method design to gain an understanding of the sources of meaning, hope, legacy and identity in advanced cancer and to explore the acceptability and feasibility of applying IMCP to Latinos diagnosed with advanced cancer. The study findings will be used to adapt the intervention manual following the Ecological Validity Model and Cultural Adaptation Process Model. To achieve these aims, we will use a two-phased convergent mixed-method design. First, we will survey 70 Spanish-speaking advanced cancer patients and 50 mental health professionals who provide services to Latino cancer patients, to assess the acceptability and feasibility of the methods, concepts and goals of IMCP. Only patients who have completed the questionnaires will be approached for the in-depth interview to triangulate the information using a convergent integration approach. Fifteen Latino patients diagnosed with advanced cancer will be interviewed to learn patients' sources of meaning following a cancer diagnosis; explore their understanding of the concepts of the IMCP model; and to help discern the acceptability and feasibility of the goals, concepts, methods and metaphors of IMCP. This will be the first therapeutic intervention adapted for Latinos diagnosed with advanced cancer. This application is responsive to the eighth priority of the NCI Strategic Plan, to study and identify factors contributing to disparities, develop culturally appropriate approaches, and disseminate interventions to overcome health disparities across the cancer control continuum from disease prevention to end-of-life care. This significant contribution will address the critical lack of palliative cancer care interventions for the Spanish- speaking population. The results of this formative study will provide guidance to this specific intervention's adaptation, but will also advance the field of cultural adaptation of psychosocial interventions with medical populations. OMB No. 0925-0001/0002 (Rev. 08/12 Approved Through 8/31/2015) Page Continuation Format Page


Family functioning and psychosocial symptoms among Latinx patients coping with advanced cancer.
Authors: Torres-Blasco N. , Castro-Figueroa E.M. , Zamore C. , Claros M. , Peña-Vargas C. , Rosario L. , Sanabria G. , Breitbart W. , Costas-Muñiz R. .
Source: Palliative & supportive care, 2023 Jun; 21(3), p. 461-464.
PMID: 36098498
Related Citations

Importance of Communication Skills Training and Meaning Centered Psychotherapy Concepts among Patients and Caregivers Coping with Advanced Cancer.
Authors: Torres-Blasco N. , Rosario-Ramos L. , Navedo M.E. , Peña-Vargas C. , Costas-Muñiz R. , Castro-Figueroa E. .
Source: International journal of environmental research and public health, 2023-03-02; 20(5), .
EPub date: 2023-03-02.
PMID: 36901468
Related Citations

Cultural adaptation process of cancer-related interventions: A step-by-step guide.
Authors: Costas-Muniz R. , Torres-Blasco N. , Gany F. , Gonzalez C.J. , Galindo-Vazquez O. , Bergerot C.D. , Rocha-Cadman X. , Lui F. , Lichtenthal W.G. , Velazquez A.I. , et al. .
Source: Psycho-oncology, 2023 Jan; 32(1), p. 179-186.
EPub date: 2022-12-04.
PMID: 36444126
Related Citations

Important End-of-Life Topics among Latino Patients and Caregivers Coping with Advanced Cancer.
Authors: Rosario-Ramos L. , Suarez K. , Peña-Vargas C. , Toro-Morales Y. , Costas-Muñiz R. , Castro E. , Torres S. , Torres-Blasco N. .
Source: International journal of environmental research and public health, 2022-07-23; 19(15), .
EPub date: 2022-07-23.
PMID: 35897338
Related Citations

Psychosocial Intervention Cultural Adaptation for Latinx Patients and Caregivers Coping with Advanced Cancer.
Authors: Torres-Blasco N. , Costas-Muñiz R. , Rosario L. , Porter L. , Suárez K. , Peña-Vargas C. , Toro-Morales Y. , Shen M. , Breitbart W. , Castro-Figueroa E.M. .
Source: Healthcare (Basel, Switzerland), 2022-07-04; 10(7), .
EPub date: 2022-07-04.
PMID: 35885770
Related Citations

Cultural adaptation of meaning-centered psychotherapy for latino families: a protocol.
Authors: Torres Blasco N. , Costas Muñiz R. , Zamore C. , Porter L. , Claros M. , Bernal G. , Shen M.J. , Breitbart W. , Castro E.M. .
Source: BMJ open, 2022-04-04; 12(4), p. e045487.
EPub date: 2022-04-04.
PMID: 35379609
Related Citations

Brief Report: Hispanic Patients' Trajectory of Cancer Symptom Burden, Depression, Anxiety, and Quality of Life.
Authors: Castro-Figueroa E.M. , Torres-Blasco N. , Rosal M.C. , Jiménez J.C. , Castro-Rodríguez W.P. , González-Lorenzo M. , Vélez-Cortés H. , Toro-Bahamonde A. , Costas-Muñiz R. , Armaiz-Peña G.N. , et al. .
Source: Nursing reports (Pavia, Italy), 2021-06-09; 11(2), p. 475-483.
EPub date: 2021-06-09.
PMID: 34968222
Related Citations

Spiritual Well-Being, Depression, and Quality of Life Among Latina Breast Cancer Survivors.
Authors: Garduño-Ortega O. , Morales-Cruz J. , Hunter-Hernández M. , Gany F. , Costas-Muñiz R. .
Source: Journal of religion and health, 2021 Jun; 60(3), p. 1895-1907.
EPub date: 2021-01-13.
PMID: 33439398
Related Citations

Barriers to Psychosocial Services Use For Latina Versus Non-Latina White Breast Cancer Survivors.
Authors: Costas-Muñiz R. , Garduño-Ortega O. , Hunter-Hernández M. , Morales J. , Castro-Figueroa E.M. , Gany F. .
Source: American journal of psychotherapy, 2021-03-01; 74(1), p. 13-21.
EPub date: 2020-10-08.
PMID: 33028079
Related Citations

Practice of psycho-oncology with Latino patients: An international study.
Authors: Costas-Muñiz R. , Castro-Figueroa E. , Torres N. , Claros M. , Galindo-Vazquez O. , Narang B. , Gany F.M. .
Source: Psycho-oncology, 2021 Jan; 30(1), p. 127-133.
EPub date: 2020-10-12.
PMID: 32914912
Related Citations

Meaning-Centered Psychotherapy for Latino Patients with Advanced Cancer: Cultural Adaptation Process.
Authors: Costas-Muñiz R. , Torres-Blasco N. , Castro-Figueroa E.M. , González C.J. , Breitbart W. , Gany F. .
Source: Journal of palliative medicine, 2020 Apr; 23(4), p. 489-497.
EPub date: 2019-10-30.
PMID: 31663811
Related Citations

Comprehension and acceptance of the Meaning-Centered Psychotherapy with a Puerto Rican patient diagnosed with advanced cancer: A case study.
Authors: Torres-Blasco N. , Castro E. , Crespo-Martín I. , Gonzalez K. , Ramirez E.P. , Garduño O. , Costas-Muñiz R. .
Source: Palliative & supportive care, 2020 Feb; 18(1), p. 103-109.
PMID: 31771680
Related Citations

Cultural Adaptation and Open Pilot of Meaning-Centered Psychotherapy for Puerto Rican Patients with Advanced Cancer.
Authors: Torres-Blasco N. , Castro-Figuero E. , Garduño-Ortega O. , Costas-Muñiz R. .
Source: Science journal of education, 2020; 8(4), p. 100-107.
EPub date: 2020-08-25.
PMID: 34532506
Related Citations

Preferences, use of and satisfaction with mental health services among a sample of Puerto Rican cancer patients.
Authors: Castro-Figueroa E.M. , Torres-Blasco N. , Rosal M.C. , Castro W.P. , González-Lorenzo M.E. , Vélez H. , Costas-Muñiz R. , Jiménez J.C. .
Source: PloS one, 2019; 14(7), p. e0216127.
EPub date: 2019-07-18.
PMID: 31318876
Related Citations

[Behavioral Medicine, Health Psychology and Psycho-oncology Puerto Rican Graduated Students Research Training Needs].
Authors: Ramírez E.P. , Blasco N.T. , Ortega O.G. , Castro E. , Muñiz R.C. .
Source: Revista Puertorriquena de psicologia, 2017 Jul-Dec; 28(2), p. 296-313.
PMID: 30505391
Related Citations

Ethnic differences in psychosocial service use among non-Latina white and Latina breast cancer survivors.
Authors: Costas-Muñiz R. , Hunter-Hernández M. , Garduño-Ortega O. , Morales-Cruz J. , Gany F. .
Source: Journal of psychosocial oncology, 2017 Jul-Aug; 35(4), p. 424-437.
EPub date: 2017-03-23.
PMID: 28332946
Related Citations

Missed Opportunity: Spirituality as a Bridge to Resilience in Latinos with Cancer.
Authors: Hunter-Hernández M. , Costas-Muñíz R. , Gany F. .
Source: Journal of religion and health, 2015 Dec; 54(6), p. 2367-75.
PMID: 25711211
Related Citations

Back to Top