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Grant Details

Grant Number: 5R01CA136940-05 Interpret this number
Primary Investigator: Champion, Victoria
Organization: Indiana Univ-Purdue Univ At Indianapolis
Project Title: Increasing Colorectal and Breast Cancer Screnning in Women
Fiscal Year: 2014


DESCRIPTION (provided by applicant): Appropriate cancer screening in women 50 and older reduces both colorectal cancer (CRC) and breast cancer (BC) mortality, but adherence to both screening behaviors is inadequate. The purpose of this proposal is to test a tailored and interactive intervention to increase both CRC and BC screening in women 51 to 75 who are non-adherent to CRC but adherent to BC (Group A) or to a group which is non-adherent to both CRC and BC (Group B) screening. The intervention is based on theoretical modeling that will simultaneously address more than one health behavior. We will compare a tailored interactive program delivered via a mailed digital video disc (TIDVD), a cancer screening call (CSC), the combination of a TIDVD + CSC, and usual care to increase CRC and BC screening during a single point of contact. Approximately 2616 women, who are members of a family care practice network and insured by Wellpoint will be assessed for eligibility. Eligible women will be either non-adherent to CRC only (Group A) or non-adherent to both CRC and BC (Group B) screening. After eligibility assessment and consent, women will be enrolled in the study and randomly assigned to the TIDVD, CSC, TIDVD + CSC, or usual care. The TIDVD program and CSC will tailor messages to recipients' perceptions of risk, benefits, barriers, and self-efficacy associated with either CRC or with CRC and BC. Interventions will encourage either CRC screening building on their success with BC screening (Group A) or will encourage both screenings simultaneously (Group B) if the woman is non-adherent to either screening. Women in interventions groups will have the ability to schedule BC or CRC screening via telephone without a clinic visit. All intervention arms can be delivered directly to the women in their homes. One week after baseline telephone assessment, interventions will be delivered. Outcomes will be obtained by telephone interviews as well as through claims data and medical records audit at 6 months. Process data about the intervention will be collected at 4 weeks post intervention. Cost effectiveness will be computed for both interventions to speed translation to practice if either or both are found to be efficacious.


Economic Evaluation of Web- versus Telephone-based Interventions to Simultaneously Increase Colorectal and Breast Cancer Screening Among Women.
Authors: Huang D. , Lairson D.R. , Chung T.H. , Monahan P.O. , Rawl S.M. , Champion V.L. .
Source: Cancer prevention research (Philadelphia, Pa.), 2021 Sep; 14(9), p. 905-916.
EPub date: 2021-07-09.
PMID: 34244154
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An RCT to Increase Breast and Colorectal Cancer Screening.
Authors: Champion V.L. , Christy S.M. , Rakowski W. , Lairson D.R. , Monahan P.O. , Gathirua-Mwangi W.G. , Stump T.E. , Biederman E.B. , Kettler C.D. , Rawl S.M. .
Source: American journal of preventive medicine, 2020 Aug; 59(2), p. e69-e78.
PMID: 32690203
Related Citations

Economic Evaluation of Tailored Web versus Tailored Telephone-Based Interventions to Increase Colorectal Cancer Screening among Women.
Authors: Lairson D.R. , Chung T.H. , Huang D. , Stump T.E. , Monahan P.O. , Christy S.M. , Rawl S.M. , Champion V.L. .
Source: Cancer prevention research (Philadelphia, Pa.), 2020 Mar; 13(3), p. 309-316.
EPub date: 2020-01-22.
PMID: 31969343
Related Citations

Impact of Tailored Interventions on Receipt of a Preference-Concordant Colorectal Cancer Screening Test.
Authors: Christy S.M. , Monahan P.O. , Stump T.E. , Rawl S.M. , Champion V.L. .
Source: Medical decision making : an international journal of the Society for Medical Decision Making, 2020 Jan; 40(1), p. 29-41.
EPub date: 2019-12-07.
PMID: 31814511
Related Citations

A Randomized Trial to Compare a Tailored Web-Based Intervention and Tailored Phone Counseling to Usual Care for Increasing Colorectal Cancer Screening.
Authors: Champion V.L. , Christy S.M. , Rakowski W. , Gathirua-Mwangi W.G. , Tarver W.L. , Carter-Harris L. , Cohee A.A. , Marley A.R. , Jessup N.M. , Biederman E. , et al. .
Source: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2018 Dec; 27(12), p. 1433-1441.
EPub date: 2018-09-04.
PMID: 30181203
Related Citations

Estimating development cost of an interactive website based cancer screening promotion program.
Authors: Lairson D.R. , Chung T.H. , Smith L.G. , Springston J.K. , Champion V.L. .
Source: Evaluation and program planning, 2015 Jun; 50, p. 56-62.
EPub date: 2015-02-23.
PMID: 25749548
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