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Grant Details

Grant Number: 5R21CA171921-02 Interpret this number
Primary Investigator: Laurenceau, Jean
Organization: University Of Delaware
Project Title: Intensive Longitudinal Study of Fear of Recurrence in Cancer Patients and Spouses
Fiscal Year: 2014
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Abstract

DESCRIPTION (provided by applicant): Breast cancer is the most common cancer in women across the US as well as developed and developing regions across the world. There are over 10 million Americans who live with a personal history of cancer and are thus considered to be cancer survivors. Among survivors, fear of cancer recurrence (FOR) is the most prevalent psychosocial concern and can be more pronounced for partners and caregivers than for the patients themselves. Despite substantial anecdotal, clinical, and cross-sectional evidence, at present there is surprisingly little known empirically about the temporal course of FOR or the factors that predict prospectively who will suffer from chronic and/or severe FOR. The behavioral research proposed in this R21 application will be the first comprehensive and intensive investigation into the everyday as well as longer-term predictors of FOR in the lives of BC survivors and their spouses/partners. This work has important implications for clinical practice guidelines for the psychosocial care of BC survivors (both patient and their significant others) including effective psychosocial-focused assessment, intervention services, and cancer survivorship programming. The proposed work represents the next step in an ongoing collaboration between behavioral science researchers at the University of Delaware and Helen F. Graham Cancer Center (an NCI-designated Community Cancer Center part of Christiana Care Health System, Newark, DE).

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Publications

Threat sensitivity and fear of cancer recurrence: a daily diary study of reactivity and recovery as patients and spouses face the first mammogram post-diagnosis.
Authors: Soriano E.C. , Perndorfer C. , Siegel S.D. , Laurenceau J.P. .
Source: Journal of psychosocial oncology, 2019 Mar-Apr; 37(2), p. 131-144.
EPub date: 2018-12-28.
PMID: 30590993
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Everyday protective buffering predicts intimacy and fear of cancer recurrence in couples coping with early-stage breast cancer.
Authors: Perndorfer C. , Soriano E.C. , Siegel S.D. , Laurenceau J.P. .
Source: Psycho-oncology, 2019 02; 28(2), p. 317-323.
EPub date: 2018-12-03.
PMID: 30426612
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Assessing the relationship between fear of cancer recurrence and health care utilization in early-stage breast cancer survivors.
Authors: Otto A.K. , Soriano E.C. , Siegel S.D. , LoSavio S.T. , Laurenceau J.P. .
Source: Journal of cancer survivorship : research and practice, 2018 12; 12(6), p. 775-785.
EPub date: 2018-10-19.
PMID: 30341560
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Social constraints and fear of recurrence in couples coping with early stage breast cancer.
Authors: Soriano E.C. , Pasipanodya E.C. , LoSavio S.T. , Otto A.K. , Perndorfer C. , Siegel S.D. , Laurenceau J.P. .
Source: Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2018 Sep; 37(9), p. 874-884.
PMID: 30138023
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Does sharing good news buffer fear of bad news? A daily diary study of fear of cancer recurrence in couples approaching the first mammogram post-diagnosis.
Authors: Soriano E.C. , Perndorfer C. , Otto A.K. , Siegel S.D. , Laurenceau J.P. .
Source: Psycho-oncology, 2018 11; 27(11), p. 2581-2586.
EPub date: 2018-07-23.
PMID: 29927016
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Checking Behavior, Fear of Recurrence, and Daily Triggers in Breast Cancer Survivors.
Authors: Soriano E.C. , Valera R. , Pasipanodya E.C. , Otto A.K. , Siegel S.D. , Laurenceau J.P. .
Source: Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2019-03-01; 53(3), p. 244-254.
PMID: 29771272
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Partner social constraints and early-stage breast cancer: Longitudinal associations with psychosexual adjustment.
Authors: Soriano E.C. , Otto A.K. , Siegel S.D. , Laurenceau J.P. .
Source: Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43), 2017 Aug; 31(5), p. 574-583.
EPub date: 2017-02-16.
PMID: 28206777
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Effects of a randomized gratitude intervention on death-related fear of recurrence in breast cancer survivors.
Authors: Otto A.K. , Szczesny E.C. , Soriano E.C. , Laurenceau J.P. , Siegel S.D. .
Source: Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2016 Dec; 35(12), p. 1320-1328.
EPub date: 2016-08-11.
PMID: 27513475
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Capitalizing on everyday positive events uniquely predicts daily intimacy and well-being in couples coping with breast cancer.
Authors: Otto A.K. , Laurenceau J.P. , Siegel S.D. , Belcher A.J. .
Source: Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43), 2015 Feb; 29(1), p. 69-79.
EPub date: 2014-12-22.
PMID: 25528074
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Social constraints on disclosure predict daily well-being in couples coping with early-stage breast cancer.
Authors: Pasipanodya E.C. , Parrish B.P. , Laurenceau J.P. , Cohen L.H. , Siegel S.D. , Graber E.C. , Belcher A.J. .
Source: Journal of family psychology : JFP : journal of the Division of Family Psychology of the American Psychological Association (Division 43), 2012 Aug; 26(4), p. 661-7.
EPub date: 2012-06-11.
PMID: 22686265
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