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Grant Details

Grant Number: 5R21CA171921-02 Interpret this number
Primary Investigator: Laurenceau, Jean
Organization: University Of Delaware
Project Title: Intensive Longitudinal Study of Fear of Recurrence in Cancer Patients and Spouses
Fiscal Year: 2014


Abstract

DESCRIPTION (provided by applicant): Breast cancer is the most common cancer in women across the US as well as developed and developing regions across the world. There are over 10 million Americans who live with a personal history of cancer and are thus considered to be cancer survivors. Among survivors, fear of cancer recurrence (FOR) is the most prevalent psychosocial concern and can be more pronounced for partners and caregivers than for the patients themselves. Despite substantial anecdotal, clinical, and cross-sectional evidence, at present there is surprisingly little known empirically about the temporal course of FOR or the factors that predict prospectively who will suffer from chronic and/or severe FOR. The behavioral research proposed in this R21 application will be the first comprehensive and intensive investigation into the everyday as well as longer-term predictors of FOR in the lives of BC survivors and their spouses/partners. This work has important implications for clinical practice guidelines for the psychosocial care of BC survivors (both patient and their significant others) including effective psychosocial-focused assessment, intervention services, and cancer survivorship programming. The proposed work represents the next step in an ongoing collaboration between behavioral science researchers at the University of Delaware and Helen F. Graham Cancer Center (an NCI-designated Community Cancer Center part of Christiana Care Health System, Newark, DE).



Publications

Fear of cancer recurrence and change in hair cortisol concentrations in partners of breast cancer survivors.
Authors: Fenech A.L. , Soriano E.C. , Asok A. , Siegel S.D. , Morreale M. , Brownlee H.A. , Laurenceau J.P. .
Source: Journal Of Cancer Survivorship : Research And Practice, 2024-07-02 00:00:00.0; , .
EPub date: 2024-07-02 00:00:00.0.
PMID: 38954249
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Daily partner responsiveness and everyday sleep outcomes in breast cancer survivors and their partners.
Authors: Fenech A.L. , Perndorfer C. , Soriano E.C. , Otto A.K. , Brownlee H.A. , Morreale M. , Siegel S.D. , Laurenceau J.P. .
Source: Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer, 2022-06-08 00:00:00.0; , .
EPub date: 2022-06-08 00:00:00.0.
PMID: 35676343
Related Citations

Fear of Cancer Recurrence and Sleep in Couples Coping With Early-Stage Breast Cancer.
Authors: Perndorfer C. , Soriano E.C. , Siegel S.D. , Spencer R.M.C. , Otto A.K. , Laurenceau J.P. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2022-05-13 00:00:00.0; , .
EPub date: 2022-05-13 00:00:00.0.
PMID: 35551585
Related Citations

The longitudinal course of emotional and cognitive factors of fear of cancer recurrence in breast cancer patients and their partners.
Authors: Otto A.K. , Soriano E.C. , LoSavio S.T. , Siegel S.D. , Perndorfer C. , Fenech A.L. , Laurenceau J.P. .
Source: Psycho-oncology, 2022-02-28 00:00:00.0; , .
EPub date: 2022-02-28 00:00:00.0.
PMID: 35226385
Related Citations

Fear of Cancer Recurrence and Inhibited Disclosure: Testing the Social-Cognitive Processing Model in Couples Coping With Breast Cancer.
Authors: Soriano E.C. , Otto A.K. , LoSavio S.T. , Perndorfer C. , Siegel S.D. , Laurenceau J.P. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2021-03-20 00:00:00.0; 55(3), p. 192-202.
PMID: 32608472
Related Citations

Threat sensitivity and fear of cancer recurrence: a daily diary study of reactivity and recovery as patients and spouses face the first mammogram post-diagnosis.
Authors: Soriano E.C. , Perndorfer C. , Siegel S.D. , Laurenceau J.P. .
Source: Journal Of Psychosocial Oncology, 2019 Mar-Apr; 37(2), p. 131-144.
EPub date: 2018-12-28 00:00:00.0.
PMID: 30590993
Related Citations

Everyday protective buffering predicts intimacy and fear of cancer recurrence in couples coping with early-stage breast cancer.
Authors: Perndorfer C. , Soriano E.C. , Siegel S.D. , Laurenceau J.P. .
Source: Psycho-oncology, 2019 Feb; 28(2), p. 317-323.
EPub date: 2018-12-03 00:00:00.0.
PMID: 30426612
Related Citations

Does sharing good news buffer fear of bad news? A daily diary study of fear of cancer recurrence in couples approaching the first mammogram post-diagnosis.
Authors: Soriano E.C. , Perndorfer C. , Otto A.K. , Siegel S.D. , Laurenceau J.P. .
Source: Psycho-oncology, 2018 Nov; 27(11), p. 2581-2586.
EPub date: 2018-07-23 00:00:00.0.
PMID: 29927016
Related Citations

Assessing the relationship between fear of cancer recurrence and health care utilization in early-stage breast cancer survivors.
Authors: Otto A.K. , Soriano E.C. , Siegel S.D. , LoSavio S.T. , Laurenceau J.P. .
Source: Journal Of Cancer Survivorship : Research And Practice, 2018-10-19 00:00:00.0; , .
EPub date: 2018-10-19 00:00:00.0.
PMID: 30341560
Related Citations

Social constraints and fear of recurrence in couples coping with early stage breast cancer.
Authors: Soriano E.C. , Pasipanodya E.C. , LoSavio S.T. , Otto A.K. , Perndorfer C. , Siegel S.D. , Laurenceau J.P. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2018 Sep; 37(9), p. 874-884.
PMID: 30138023
Related Citations

Checking Behavior, Fear of Recurrence, and Daily Triggers in Breast Cancer Survivors.
Authors: Soriano E.C. , Valera R. , Pasipanodya E.C. , Otto A.K. , Siegel S.D. , Laurenceau J.P. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2018-05-16 00:00:00.0; , .
EPub date: 2018-05-16 00:00:00.0.
PMID: 29771272
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Effects Of A Randomized Gratitude Intervention On Death-related Fear Of Recurrence In Breast Cancer Survivors
Authors: Otto A.K. , Szczesny E.C. , Soriano E.C. , Laurenceau J.P. , Siegel S.D. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2016 Dec; 35(12), p. 1320-1328.
PMID: 27513475
Related Citations

Capitalizing on everyday positive events uniquely predicts daily intimacy and well-being in couples coping with breast cancer.
Authors: Otto A.K. , Laurenceau J.P. , Siegel S.D. , Belcher A.J. .
Source: Journal Of Family Psychology : Jfp : Journal Of The Division Of Family Psychology Of The American Psychological Association (division 43), 2015 Feb; 29(1), p. 69-79.
PMID: 25528074
Related Citations

An electronic diary study of the effects of patient avoidance and partner social constraints on patient momentary affect in metastatic breast cancer.
Authors: Badr H. , Pasipanodya E.C. , Laurenceau J.P. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2013 Apr; 45(2), p. 192-202.
PMID: 23150234
Related Citations

Social Constraints On Disclosure Predict Daily Well-being In Couples Coping With Early-stage Breast Cancer
Authors: Pasipanodya E.C. , Parrish B.P. , Laurenceau J.P. , Cohen L.H. , Siegel S.D. , Graber E.C. , Belcher A.J. .
Source: Journal Of Family Psychology : Jfp : Journal Of The Division Of Family Psychology Of The American Psychological Association (division 43), 2012 Aug; 26(4), p. 661-7.
PMID: 22686265
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