Skip to main content
An official website of the United States government
Grant Details

Grant Number: 5R21CA167691-02 Interpret this number
Primary Investigator: Hinson, John
Organization: Washington State University
Project Title: Information Throughput in Risky Decision Making Underlying Self-Regulation
Fiscal Year: 2012


DESCRIPTION (provided by applicant): Behavioral self-regulation is often based on decision making processes that involve risk and ambiguity. Further, risky decision making can depend on non-affective, deliberative processes (cold cognition), affective, automatic processes (hot cognition), or the interaction of these processes. The role of hot cognition is paradoxical in that affect sometimes appears to interfere with good decision making and sometimes seems to facilitate good decision making. Because of this, it is unclear whether in a given situation suboptimal decision making is due to insufficient or unutilized cold cognitive information, or due to inappropriately weighting of cold cognitive information along with hot cognitive information. The proposed research will examine when cold cognitive information is available and when it is properly used in risky decision making tasks in three specific aims. First, we will assess the fate of cold cognitive information and determine the impact on frame-induced decision making bias in a traditional risky decision making task with experimental challenges to hot and cold cognition. Second, we will assess the fate of cold cognitive information and determine the impact on frame-induced decision making in the newly developed Framed Gambling Task, which allows better analysis of risk and ambiguity, also with challenges to hot and cold cognition. Third, we assess the fate of cold cognitive information and determine the impact on frame-induced decision making in a sleep deprivation challenge. This research will help to identify factors that impede decision making processes necessary for good self-regulation. Extending the research from artificial laboratory challenges to a realistic sleep deprivation challenge will assist in designing interventions and environments to reduce the impact of suboptimal decision on safety, health and well-being in daily life.


Sleep deprivation impairs binding of information with its context.
Authors: Kurinec C.A. , Whitney P. , Hinson J.M. , Hansen D.A. , Van Dongen H.P.A. .
Source: Sleep, 2021-08-13; 44(8), .
PMID: 33940625
Related Citations

Working memory loads differentially influence frame-induced bias and normative choice in risky decision making.
Authors: Hinson J.M. , Whitney P. , Wilson C.G. , Nusbaum A.T. .
Source: PloS one, 2019; 14(3), p. e0214571.
EPub date: 2019-03-28.
PMID: 30921395
Related Citations

Total sleep deprivation does not significantly degrade semantic encoding.
Authors: Honn K.A. , Grant D.A. , Hinson J.M. , Whitney P. , Van Dongen H. .
Source: Chronobiology international, 2018 Jun; 35(6), p. 746-749.
EPub date: 2018-01-17.
PMID: 29341785
Related Citations

Catechol-O-methyltransferase (COMT) genotype affects cognitive control during total sleep deprivation.
Authors: Satterfield B.C. , Hinson J.M. , Whitney P. , Schmidt M.A. , Wisor J.P. , Van Dongen H.P.A. .
Source: Cortex; a journal devoted to the study of the nervous system and behavior, 2018 Feb; 99, p. 179-186.
EPub date: 2017-11-26.
PMID: 29248857
Related Citations

Time-on-Task Effect During Sleep Deprivation in Healthy Young Adults Is Modulated by Dopamine Transporter Genotype.
Authors: Satterfield B.C. , Wisor J.P. , Schmidt M.A. , Van Dongen H.P.A. .
Source: Sleep, 2017-12-01; 40(12), .
PMID: 29029252
Related Citations

Signal-to-Noise Ratio in PVT Performance as a Cognitive Measure of the Effect of Sleep Deprivation on the Fidelity of Information Processing.
Authors: Chavali V.P. , Riedy S.M. , Van Dongen H.P. .
Source: Sleep, 2017-03-01; 40(3), .
PMID: 28364430
Related Citations

TNFα G308A polymorphism is associated with resilience to sleep deprivation-induced psychomotor vigilance performance impairment in healthy young adults.
Authors: Satterfield B.C. , Wisor J.P. , Field S.A. , Schmidt M.A. , Van Dongen H.P. .
Source: Brain, behavior, and immunity, 2015 Jul; 47, p. 66-74.
EPub date: 2014-12-24.
PMID: 25542735
Related Citations

Feedback Blunting: Total Sleep Deprivation Impairs Decision Making that Requires Updating Based on Feedback.
Authors: Whitney P. , Hinson J.M. , Jackson M.L. , Van Dongen H.P. .
Source: Sleep, 2015-05-01; 38(5), p. 745-54.
EPub date: 2015-05-01.
PMID: 25515105
Related Citations

Deconstructing and reconstructing cognitive performance in sleep deprivation.
Authors: Jackson M.L. , Gunzelmann G. , Whitney P. , Hinson J.M. , Belenky G. , Rabat A. , Van Dongen H.P. .
Source: Sleep medicine reviews, 2013 Jun; 17(3), p. 215-25.
EPub date: 2012-08-09.
PMID: 22884948
Related Citations

Back to Top