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Grant Details

Grant Number: 5R01CA133068-04 Interpret this number
Primary Investigator: Catley, Delwyn
Organization: University Of Missouri Kansas City
Project Title: Can Motivational Interviewing Be Effective for Smoking Cessation?
Fiscal Year: 2012


DESCRIPTION (provided by applicant): Tobacco smoking remains one of the most significant preventable causes of death in the U.S. Although most smokers are interested in quitting, only one in five are ready to make a quit attempt at any point in time. Unfortunately, few interventions designed to enhance motivation or readiness among smokers who are not ready to quit are available. One intervention method that focuses on enhancing motivation for and commitment to behavior change is Motivational Interviewing (MI). MI has been shown to be effective for addressing a variety of addictive and health behaviors, however findings for smoking cessation have been overwhelmingly negative and all prior studies have significant limitations. One important limitation of prior studies is that they were not designed to directly test whether MI is more effective for smokers who are not ready to quit, and in particular, whether MI was more effective at motivating quit attempts. Moreover, nearly all focused on special populations such as public housing residents, adolescents, and people with mental illness, many of whom face significant environmental and physiological barriers to quitting. Therefore, the primary aim of this study is to test, among a sample of general adult smokers, the effectiveness of MI for motivating quit attempts among smokers not yet ready to quit. We will randomly assign eligible smokers to Motivational Interviewing (MI), a PHS Guidelines-based counseling control (GBC), or brief advice (BA). The primary outcome will be the occurrence (or not) of any self-reported quit attempt lasting at least 24 hours between randomization and 6 month follow-up. The secondary aim will be to examine 6 month follow-up quit rates between the groups in order to provide an effect size estimate that could be used in designing a large scale study with a primary outcome of smoking cessation. Participants in BA will receive 1 session and participants MI and GBC will receive 5 individual sessions (2 in-person, 3 phone) over 7 weeks. All participants who decide to quit will be provided with varenicline (Chantix). We project needing to enroll 255 smokers who are not ready to quit to detect the proposed treatment effect. PUBLIC HEALTH RELEVANCE: Tobacco smoking remains one of the most significant preventable causes of death in the U.S. and although most smokers are interested in quitting, four in five are not ready to make a quit attempt at any given point in time. This project addresses the lack of methods designed to increase readiness to quit by testing a novel counseling method known as Motivational Interviewing. The potential public health impact is large because it could extend the reach of effective cessation interventions to the majority of smokers who are unmotivated and reduce the decades-long lag between smoking initiation and cessation.


Differential mechanisms of change in motivational interviewing versus health education for smoking cessation induction.
Authors: Catley D. , Grobe J. , Moreno J.L. , Stortz S. , Fox A.T. , Bradley-Ewing A. , Richter K.P. , Resnicow K. , Harris K.J. , Goggin K. .
Source: Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors, 2021 Nov; 35(7), p. 778-787.
EPub date: 2021-04-01.
PMID: 33793282
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Stress, Depression and Quit Attempt Outcomes among Unmotivated Smokers.
Authors: Arana-Chicas E. , Cupertino A.P. , Goggin K. , Richter K.P. , Harris K.J. , Catley D. .
Source: Substance use & misuse, 2021; 56(10), p. 1564-1568.
EPub date: 2021-06-15.
PMID: 34130595
Related Citations

Motivational Interviewing to Encourage Quit Attempts Among Smokers Not Ready to Quit: A Trial-Based Economic Analysis.
Authors: Rasu R.S. , Thelen J. , Agbor Bawa W. , Goggin K. , Bradley-Ewing A. , Catley D. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2020-08-24; 22(9), p. 1515-1523.
PMID: 31820002
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Race moderates the effects of Motivational Interviewing on smoking cessation induction.
Authors: Grobe J.E. , Goggin K. , Harris K.J. , Richter K.P. , Resnicow K. , Catley D. .
Source: Patient education and counseling, 2020 Feb; 103(2), p. 350-358.
EPub date: 2019-08-18.
PMID: 31466882
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Effectiveness of motivational interviewing, health education and brief advice in a population of smokers who are not ready to quit.
Authors: Bani-Yaghoub M. , Elhomani A. , Catley D. .
Source: BMC medical research methodology, 2018-06-13; 18(1), p. 52.
EPub date: 2018-06-13.
PMID: 29895280
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Implicit Attitudes and Smoking Behavior in a Smoking Cessation Induction Trial.
Authors: Lee H.S. , Addicott M. , Martin L.E. , Harris K.J. , Goggin K. , Richter K.P. , Patten C.A. , McClernon F.J. , Fleming K. , Catley D. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2017-12-13; 20(1), p. 58-66.
PMID: 27679606
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Executive function fails to predict smoking outcomes in a clinical trial to motivate smokers to quit.
Authors: Fox A.T. , Martin L.E. , Bruce J. , Moreno J.L. , Staggs V.S. , Lee H.S. , Goggin K. , Harris K.J. , Richter K. , Patten C. , et al. .
Source: Drug and alcohol dependence, 2017-06-01; 175, p. 227-231.
EPub date: 2017-04-13.
PMID: 28458075
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Recruiting unmotivated smokers into a smoking induction trial.
Authors: Harris K.J. , Bradley-Ewing A. , Goggin K. , Richter K.P. , Patten C. , Williams K. , Lee H.S. , Staggs V.S. , Catley D. .
Source: Health education research, 2016 Jun; 31(3), p. 363-74.
EPub date: 2016-04-13.
PMID: 27081187
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A Randomized Trial of Motivational Interviewing: Cessation Induction Among Smokers With Low Desire to Quit.
Authors: Catley D. , Goggin K. , Harris K.J. , Richter K.P. , Williams K. , Patten C. , Resnicow K. , Ellerbeck E.F. , Bradley-Ewing A. , Lee H.S. , et al. .
Source: American journal of preventive medicine, 2016 May; 50(5), p. 573-583.
EPub date: 2015-12-23.
PMID: 26711164
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Exploring the Severity of Dependence Scale (SDS) as a possible measure of nicotine dependence.
Authors: Mercincavage M. , Smyth J.M. , Branstetter S.A. , Catley D. .
Source: Substance abuse, 2016 Apr-Jun; 37(2), p. 323-9.
EPub date: 2015-11-13.
PMID: 26566575
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Relationship of Autonomy Social Support to Quitting Motivation in Diverse Smokers.
Authors: Patten C.A. , Clinic M. , Goggin K. , Harris K.J. , Richter K. , Williams K. , Decker P.A. , Clinic M. , Bradley-Ewing A. , Catley D. .
Source: Addiction research & theory, 2016; 24(6), p. 477-482.
EPub date: 2016-04-30.
PMID: 27833474
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A qualitative assessment of provider perspectives on smoking cessation counselling.
Authors: Champassak S.L. , Goggin K. , Finocchario-Kessler S. , Farris M. , Ehtesham M. , Schoor R. , Catley D. .
Source: Journal of evaluation in clinical practice, 2014 Jun; 20(3), p. 281-7.
EPub date: 2014-03-14.
PMID: 24628799
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Physician smoking cessation counseling and adherence to a clinical practice guideline.
Authors: Champassak S.L. , Catley D. , Finocchario-Kessler S. , Farris M. , Ehtesham M. , Schoor R. , Goggin K. .
Source: European journal for person centered healthcare, 2014; 2(4), p. 477-484.
PMID: 26279853
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African American smokers' intention to use pharmacotherapy for cessation.
Authors: Lynam I. , Catley D. , Harris K.J. , Goggin K. , Berkley-Patton J. , Thomas J. .
Source: American journal of health behavior, 2012 Sep; 36(5), p. 615-27.
PMID: 22584089
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Motivational Interviewing for encouraging quit attempts among unmotivated smokers: study protocol of a randomized, controlled, efficacy trial.
Authors: Catley D. , Harris K.J. , Goggin K. , Richter K. , Williams K. , Patten C. , Resnicow K. , Ellerbeck E. , Bradley-Ewing A. , Malomo D. , et al. .
Source: BMC public health, 2012-06-19; 12, p. 456.
EPub date: 2012-06-19.
PMID: 22713093
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