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Grant Details

Grant Number: 5R01CA098663-07 Interpret this number
Primary Investigator: Palmer, Julie
Organization: Boston University Medical Campus
Project Title: Gene Polymorphisms in Relation to Cancer in Black Women
Fiscal Year: 2012


Abstract

DESCRIPTION (provided by applicant): African American (AA) women have a higher incidence of breast cancer at young ages and higher mortality from breast cancer at all ages than white women, but are understudied with regard to the genetic etiology. Epidemiologic studies of the genetics of breast cancer have largely focused on European ancestry (EA) populations. Under the current grant, we successfully obtained mouthwash-swish saliva samples from ~27,000 Black Women's Health Study (BWHS) participants, including 1,200 breast cancer cases. We used DNA from breast cancer cases and matched controls to genotype a dense set of tagSNPs for genetic loci that had been associated with breast cancer risk in genome-wide association scans (GWAS) of EA or Asian ancestry populations. In two of those regions, 5p12 and 16q12, we identified new SNPs associated with breast cancer in AA women. We also carried out fast-track replication of the top 5 SNPs from the only collaborative AA GWAS of breast cancer yet conducted, thus helping to identify a novel SNP. In this competing continuation, we propose to follow up our BWHS findings by targeted resequencing of the 5p12 and 16q12 regions in germline DNA from 50 BWHS subjects to identify all other mutations in the regions; we will then assess associations with each of the new variants in our entire set of cases and controls. We will increase the power of the collaborative AA GWAS to discover variants associated with breast cancer by genotyping the 1,500 SNPs with lowest p-values in Stage 1 in a nested case-control study of 1,200 case-control pairs within the BWHS. We will then combine these findings with our observational data to investigate gene-environment interactions with important anthropometric and reproductive factors in 1,100 incident breast cancer cases and 2,200 controls. Many AA women are vitamin D deficient. In another aim, we will examine the relation of vitamin D to incidence of breast cancer in the 1100 incident cases and their 2200 matched controls. A prediction model for vitamin D based on BMI, physical activity, latitude and dietary and supplemental vitamin D intake has proved useful in EA studies of vitamin D and cancer. We propose to extend the model, which would be inadequate in AA women because of the major role of skin pigmentation in determining vitamin D levels, by adding data on skin pigmentation genes and vitamin D receptor and binding protein genes. The prediction model will be developed and validated based on 520 blood samples from BWHS participants. In our final aim, we will use BWHS samples to improve power of the first yet AA GWAS of age at menarche to discover variants associated with this phenotype by genotyping in a sample of 3000 BWHS participants the 1,500 tagSNPs that achieved the highest significance levels in a Stage 1 AA GWAS of age at menarche. Thus, the proposed study will aid discovery of genetic variants associated with breast cancer and age at menarche in AA women, will carry out the first assessment of important potential gene-environment interactions in AA women, and will provide novel data on the association of vitamin D with breast cancer incidence in AA women.



Publications

Genome-wide meta-analysis identifies novel risk loci for uterine fibroids within and across multiple ancestry groups.
Authors: Kim J. , Williams A. , Noh H. , Jasper E.A. , Jones S.H. , Jaworski J.A. , Shuey M.M. , Ruiz-Narváez E.A. , Wise L.A. , Palmer J.R. , et al. .
Source: Nature Communications, 2025-03-06 00:00:00.0; 16(1), p. 2273.
EPub date: 2025-03-06 00:00:00.0.
PMID: 40050615
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Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia.
Authors: Ochs-Balcom H.M. , Preus L. , Du Z. , Elston R.C. , Teerlink C.C. , Jia G. , Guo X. , Cai Q. , Long J. , Ping J. , et al. .
Source: Human Molecular Genetics, 2024-01-23 00:00:00.0; , .
EPub date: 2024-01-23 00:00:00.0.
PMID: 38263910
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Influence of alcohol consumption and alcohol metabolism variants on breast cancer risk among Black women: results from the AMBER consortium.
Authors: Young K.L. , Olshan A.F. , Lunetta K. , Graff M. , Williams L.A. , Yao S. , Zirpoli G.R. , Troester M. , Palmer J.R. .
Source: Breast Cancer Research : Bcr, 2023-06-12 00:00:00.0; 25(1), p. 66.
EPub date: 2023-06-12 00:00:00.0.
PMID: 37308906
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mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women's Circle of Health Study.
Authors: Ilozumba M.N. , Yaghjyan L. , Datta S. , Zhao J. , Hong C.C. , Lunetta K.L. , Zirpoli G. , Bandera E.V. , Palmer J.R. , Yao S. , et al. .
Source: European Journal Of Nutrition, 2023-05-20 00:00:00.0; , .
EPub date: 2023-05-20 00:00:00.0.
PMID: 37209192
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mTOR pathway candidate genes and physical activity interaction on breast cancer risk in black women from the women's circle of health study.
Authors: Ilozumba M.N. , Yaghjyan L. , Datta S. , Zhao J. , Gong Z. , Hong C.C. , Lunetta K.L. , Zirpoli G. , Bandera E.V. , Palmer J.R. , et al. .
Source: Breast Cancer Research And Treatment, 2023-03-08 00:00:00.0; , .
EPub date: 2023-03-08 00:00:00.0.
PMID: 36882608
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mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women's Circle of Health Study.
Authors: Ilozumba M.N. , Yaghjyan L. , Datta S. , Zhao J. , Hong C.C. , Lunetta K.L. , Zirpoli G. , Bandera E.V. , Palmer J.R. , Yao S. , et al. .
Source: Cancer Causes & Control : Ccc, 2023-02-15 00:00:00.0; , .
EPub date: 2023-02-15 00:00:00.0.
PMID: 36790512
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Associations between quantitative measures of TDLU involution and breast tumor molecular subtypes among breast cancer cases in the Black Women's Health Study: a case-case analysis.
Authors: Davis Lynn B.C. , Lord B.D. , Cora R. , Pfeiffer R.M. , Lawrence S. , Zirpoli G. , Bethea T.N. , Palmer J.R. , Gierach G.L. .
Source: Breast Cancer Research : Bcr, 2022-12-05 00:00:00.0; 24(1), p. 86.
EPub date: 2022-12-05 00:00:00.0.
PMID: 36471360
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Associations between quantitative measures of TDLU involution and breast tumor molecular subtypes among breast cancer cases in the Black Women's Health Study: a case-case analysis.
Authors: Davis Lynn B.C. , Lord B.D. , Cora R. , Pfeiffer R.M. , Lawrence S. , Zirpoli G. , Bethea T.N. , Palmer J.R. , Gierach G.L. .
Source: Breast Cancer Research : Bcr, 2022-12-05 00:00:00.0; 24(1), p. 86.
EPub date: 2022-12-05 00:00:00.0.
PMID: 36471360
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Depression, religiosity, and telomere length in the Study on Stress, Spirituality, and Health (SSSH).
Authors: Isehunwa O.O. , Warner E.T. , Spiegelman D. , Zhang Y. , Palmer J.R. , Kanaya A.M. , Cole S.A. , Tworoger S.S. , Shields L.O. , Gu Y. , et al. .
Source: International Journal Of Mental Health And Addiction, 2022 Jun; 20(3), p. 1465-1484.
EPub date: 2021-01-04 00:00:00.0.
PMID: 35747346
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Polygenic Risk Scores for Prediction of Breast Cancer Risk in Women of African Ancestry: a Cross-Ancestry Approach.
Authors: Gao G. , Zhao F. , Ahearn T.U. , Lunetta K.L. , Troester M.A. , Du Z. , Ogundiran T.O. , Ojengbede O. , Blot W. , Nathanson K.L. , et al. .
Source: Human Molecular Genetics, 2022-05-12 00:00:00.0; , .
EPub date: 2022-05-12 00:00:00.0.
PMID: 35554533
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Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast.
Authors: Yadav S. , Hu C. , Nathanson K.L. , Weitzel J.N. , Goldgar D.E. , Kraft P. , Gnanaolivu R.D. , Na J. , Huang H. , Boddicker N.J. , et al. .
Source: Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology, 2021-12-10 00:00:00.0; 39(35), p. 3918-3926.
EPub date: 2021-10-21 00:00:00.0.
PMID: 34672684
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Nutritional Formulation for Patients with Angelman Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study of Exogenous Ketones.
Authors: Carson R.P. , Herber D.L. , Pan Z. , Phibbs F. , Key A.P. , Gouelle A. , Ergish P. , Armour E.A. , Patel S. , Duis J. .
Source: The Journal Of Nutrition, 2021-12-03 00:00:00.0; 151(12), p. 3628-3636.
PMID: 34510212
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Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women.
Authors: Adedokun B. , Du Z. , Gao G. , Ahearn T.U. , Lunetta K.L. , Zirpoli G. , Figueroa J. , John E.M. , Bernstein L. , Zheng W. , et al. .
Source: Nature Communications, 2021-07-07 00:00:00.0; 12(1), p. 4198.
EPub date: 2021-07-07 00:00:00.0.
PMID: 34234117
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Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche.
Authors: Sarnowski C. , Cousminer D.L. , Franceschini N. , Raffield L.M. , Jia G. , Fernández-Rhodes L. , Grant S.F.A. , Hakonarson H. , Lange L.A. , Long J. , et al. .
Source: Human Reproduction (oxford, England), 2021-06-18 00:00:00.0; 36(7), p. 1999-2010.
PMID: 34021356
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Risk of Breast Cancer Among Carriers of Pathogenic Variants in Breast Cancer Predisposition Genes Varies by Polygenic Risk Score.
Authors: Gao C. , Polley E.C. , Hart S.N. , Huang H. , Hu C. , Gnanaolivu R. , Lilyquist J. , Boddicker N.J. , Na J. , Ambrosone C.B. , et al. .
Source: Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology, 2021-06-08 00:00:00.0; , p. JCO2001992.
EPub date: 2021-06-08 00:00:00.0.
PMID: 34101481
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A Population-Based Study of Genes Previously Implicated in Breast Cancer.
Authors: Hu C. , Hart S.N. , Gnanaolivu R. , Huang H. , Lee K.Y. , Na J. , Gao C. , Lilyquist J. , Yadav S. , Boddicker N.J. , et al. .
Source: The New England Journal Of Medicine, 2021-01-20 00:00:00.0; , .
EPub date: 2021-01-20 00:00:00.0.
PMID: 33471974
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Epidemiology of Basal-like and Luminal Breast Cancers among Black Women in the AMBER Consortium.
Authors: Benefield H.C. , Zirpoli G.R. , Allott E.H. , Shan Y. , Hurson A.N. , Omilian A.R. , Khoury T. , Hong C.C. , Olshan A.F. , Bethea T.N. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2021 01; 30(1), p. 71-79.
EPub date: 2020-10-23 00:00:00.0.
PMID: 33097496
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Genetic variants in anti-Müllerian hormone-related genes and breast cancer risk: results from the AMBER consortium.
Authors: Nichols H.B. , Graff M. , Bensen J.T. , Lunetta K.L. , O'Brien K.M. , Troester M.A. , Williams L.A. , Young K. , Hong C.C. , Yao S. , et al. .
Source: Breast Cancer Research And Treatment, 2020-09-22 00:00:00.0; , .
EPub date: 2020-09-22 00:00:00.0.
PMID: 32960377
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Contribution of Germline Predisposition Gene Mutations to Breast Cancer Risk in African American Women.
Authors: Palmer J.R. , Polley E.C. , Hu C. , John E.M. , Haiman C. , Hart S.N. , Gaudet M. , Pal T. , Anton-Culver H. , Trentham-Dietz A. , et al. .
Source: Journal Of The National Cancer Institute, 2020-05-19 00:00:00.0; , .
EPub date: 2020-05-19 00:00:00.0.
PMID: 32427313
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Clinical and genetic risk factors for aromatase inhibitor-associated arthralgia in breast cancer survivors.
Authors: Romero S.A.D. , Su H.I. , Satagopan J. , Li Q.S. , Seluzicki C.M. , Dries A. , DeMichele A.M. , Mao J.J. .
Source: Breast (edinburgh, Scotland), 2020 Feb; 49, p. 48-54.
EPub date: 2019-10-22 00:00:00.0.
PMID: 31678641
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Physical and sexual abuse in childhood and adolescence and leukocyte telomere length: A pooled analysis of the study on psychosocial stress, spirituality, and health.
Authors: Warner E.T. , Zhang Y. , Gu Y. , Taporoski T.P. , Pereira A. , DeVivo I. , Spence N.D. , Cozier Y. , Palmer J.R. , Kanaya A.M. , et al. .
Source: Plos One, 2020; 15(10), p. e0241363.
EPub date: 2020-10-30 00:00:00.0.
PMID: 33125425
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Risk factors for estrogen receptor positive ductal carcinoma in situ of the breast in African American women.
Authors: Bertrand K.A. , Bethea T.N. , Rosenberg L. , Bandera E.V. , Khoury T. , Troester M.A. , Ambrosone C.B. , Palmer J.R. .
Source: Breast (edinburgh, Scotland), 2019-11-06 00:00:00.0; 49, p. 108-114.
EPub date: 2019-11-06 00:00:00.0.
PMID: 31786415
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Oral Health in Relation to Pancreatic Cancer Risk in African American Women.
Authors: Gerlovin H. , Michaud D.S. , Cozier Y.C. , Palmer J.R. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2019 Apr; 28(4), p. 675-679.
EPub date: 2019-03-28 00:00:00.0.
PMID: 30923045
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Admixture mapping and fine-mapping of type 2 diabetes susceptibility loci in African American women.
Authors: Uribe-Salazar J.M. , Palmer J.R. , Haddad S.A. , Rosenberg L. , Ruiz-Narváez E.A. .
Source: Journal Of Human Genetics, 2018-08-22 00:00:00.0; , .
EPub date: 2018-08-22 00:00:00.0.
PMID: 30135545
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Admixture mapping and fine-mapping of birth weight loci in the Black Women's Health Study.
Authors: Ochs-Balcom H.M. , Shaw H. , Preus L. , Palmer J.R. , Haddad S.A. , Rosenberg L. , Ruiz-Narváez E.A. .
Source: Human Genetics, 2018-07-13 00:00:00.0; , .
EPub date: 2018-07-13 00:00:00.0.
PMID: 30006737
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Association of Degree of European Genetic Ancestry With Serum Vitamin D Levels in African Americans.
Authors: Haddad S.A. , Ruiz-Narváez E.A. , Cozier Y.C. , Gerlovin H. , Rosenberg L. , Palmer J.R. .
Source: American Journal Of Epidemiology, 2018-07-01 00:00:00.0; 187(7), p. 1420-1423.
PMID: 29390092
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A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women.
Authors: Bensen J.T. , Graff M. , Young K.L. , Sethupathy P. , Parker J. , Pecot C.V. , Currin K. , Haddad S.A. , Ruiz-Narváez E.A. , Haiman C.A. , et al. .
Source: Breast Cancer Research : Bcr, 2018-06-05 00:00:00.0; 20(1), p. 45.
EPub date: 2018-06-05 00:00:00.0.
PMID: 29871690
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Genetic ancestry and population differences in levels of inflammatory cytokines in women: Role for evolutionary selection and environmental factors.
Authors: Yao S. , Hong C.C. , Ruiz-Narváez E.A. , Evans S.S. , Zhu Q. , Schaefer B.A. , Yan L. , Coignet M.V. , Lunetta K.L. , Sucheston-Campbell L.E. , et al. .
Source: Plos Genetics, 2018 06; 14(6), p. e1007368.
EPub date: 2018-06-07 00:00:00.0.
PMID: 29879116
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Frequency of breast cancer subtypes among African American women in the AMBER consortium.
Authors: Allott E.H. , Geradts J. , Cohen S.M. , Khoury T. , Zirpoli G.R. , Bshara W. , Davis W. , Omilian A. , Nair P. , Ondracek R.P. , et al. .
Source: Breast Cancer Research : Bcr, 2018-02-06 00:00:00.0; 20(1), p. 12.
EPub date: 2018-02-06 00:00:00.0.
PMID: 29409530
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Genetic variants in immune-related pathways and breast cancer risk in African American women in the AMBER consortium.
Authors: Hong C.C. , Sucheston-Campbell L.E. , Liu S. , Hu Q. , Yao S. , Lunetta K.L. , Haddad S.A. , Ruiz-Narváez E.A. , Bensen J.T. , Cheng T.D. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2018-01-16 00:00:00.0; , .
EPub date: 2018-01-16 00:00:00.0.
PMID: 29339359
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Biology and Etiology of Young-Onset Breast Cancers among Premenopausal African American Women: Results from the AMBER Consortium.
Authors: Chollet-Hinton L. , Olshan A.F. , Nichols H.B. , Anders C.K. , Lund J.L. , Allott E.H. , Bethea T.N. , Hong C.C. , Cohen S.M. , Khoury T. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2017 Dec; 26(12), p. 1722-1729.
EPub date: 2017-09-13 00:00:00.0.
PMID: 28903991
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A multi-stage genome-wide association study of uterine fibroids in African Americans.
Authors: Hellwege J.N. , Jeff J.M. , Wise L.A. , Gallagher C.S. , Wellons M. , Hartmann K.E. , Jones S.F. , Torstenson E.S. , Dickinson S. , Ruiz-Narváez E.A. , et al. .
Source: Human Genetics, 2017-08-23 00:00:00.0; , .
EPub date: 2017-08-23 00:00:00.0.
PMID: 28836065
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Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.
Authors: Wang H. , Schmit S.L. , Haiman C.A. , Keku T.O. , Kato I. , Palmer J.R. , van den Berg D. , Wilkens L.R. , Burnett T. , Conti D.V. , et al. .
Source: International Journal Of Cancer, 2017-06-15 00:00:00.0; 140(12), p. 2728-2733.
EPub date: 2017-06-15 00:00:00.0.
PMID: 28295283
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Alcohol Intake and Breast Cancer Risk in African American Women from the AMBER Consortium.
Authors: Williams L.A. , Olshan A.F. , Hong C.C. , Bandera E.V. , Rosenberg L. , Cheng T.D. , Lunetta K.L. , McCann S.E. , Poole C. , Kolonel L.N. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2017 May; 26(5), p. 787-794.
EPub date: 2017-04-18 00:00:00.0.
PMID: 28420652
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Characterizing Genetic Susceptibility To Breast Cancer In Women Of African Ancestry
Authors: Feng Y. , Rhie S.K. , Huo D. , Ruiz-Narvaez E.A. , Haddad S.A. , Ambrosone C.B. , John E.M. , Bernstein L. , Zheng W. , Hu J.J. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2017-04-04 00:00:00.0; , .
PMID: 28377418
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Trans-ethnic Follow-up Of Breast Cancer Gwas Hits Using The Preferential Linkage Disequilibrium Approach
Authors: Zhu Q. , Shepherd L. , Lunetta K.L. , Yao S. , Liu Q. , Hu Q. , Haddad S.A. , Sucheston-Campbell L. , Bensen J.T. , Bandera E.V. , et al. .
Source: Oncotarget, 2016-12-13 00:00:00.0; 7(50), p. 83160-83176.
PMID: 27825120
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FASN, dietary fat intake, and risk of uterine leiomyomata in the Black Women's Health Study.
Authors: Wise L.A. , Palmer J.R. , Rosenberg L. , Haddad S.A. , Ruiz-Narváez E.A. .
Source: Fertility And Sterility, 2016 Oct; 106(5), p. 1136-1141.
PMID: 27375065
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Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium.
Authors: Zhang J. , Yao S. , Hu Q. , Zhu Q. , Liu S. , Lunetta K.L. , Haddad S.A. , Yang N. , Shen H. , Hong C.C. , et al. .
Source: Carcinogenesis, 2016 Oct; 37(10), p. 951-956.
EPub date: 2016-08-01 00:00:00.0.
PMID: 27485598
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An exome-wide analysis of low frequency and rare variants in relation to risk of breast cancer in African American Women: the AMBER Consortium.
Authors: Haddad S.A. , Ruiz-Narváez E.A. , Haiman C.A. , Sucheston-Campbell L.E. , Bensen J.T. , Zhu Q. , Liu S. , Yao S. , Bandera E.V. , Rosenberg L. , et al. .
Source: Carcinogenesis, 2016 Sep; 37(9), p. 870-877.
EPub date: 2016-06-07 00:00:00.0.
PMID: 27267999
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Vigorous Physical Activity And Risk Of Breast Cancer In The African American Breast Cancer Epidemiology And Risk Consortium
Authors: Gong Z. , Hong C.C. , Bandera E.V. , Adams-Campbell L.L. , Troester M.A. , Park S.Y. , McInerney K.A. , Zirpoli G. , Olshan A.F. , Palmer J.R. , et al. .
Source: Breast Cancer Research And Treatment, 2016 Sep; 159(2), p. 347-56.
PMID: 27514396
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Genome-wide Association Study Confirms Lung Cancer Susceptibility Loci On Chromosomes 5p15 And 15q25 In An African-american Population
Authors: Zanetti K.A. , Wang Z. , Aldrich M. , Amos C.I. , Blot W.J. , Bowman E.D. , Burdette L. , Cai Q. , Caporaso N. , Chung C.C. , et al. .
Source: Lung Cancer (amsterdam, Netherlands), 2016 Aug; 98, p. 33-42.
PMID: 27393504
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Predictors of biospecimen donation in the Black Women's Health Study.
Authors: Adams-Campbell L.L. , Dash C. , Palmer J.R. , Wiedemeier M.V. , Russell C.W. , Rosenberg L. , Cozier Y.C. .
Source: Cancer Causes & Control : Ccc, 2016 06; 27(6), p. 797-803.
PMID: 27106577
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Genetic variations in vitamin D-related pathways and breast cancer risk in African American women in the AMBER consortium.
Authors: Yao S. , Haddad S.A. , Hu Q. , Liu S. , Lunetta K.L. , Ruiz-Narvaez E.A. , Hong C.C. , Zhu Q. , Sucheston-Campbell L. , Cheng T.Y. , et al. .
Source: International Journal Of Cancer, 2016-05-01 00:00:00.0; 138(9), p. 2118-26.
EPub date: 2016-05-01 00:00:00.0.
PMID: 26650177
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Genetic Variants In The Mtor Pathway And Breast Cancer Risk In African American Women
Authors: Cheng T.Y. , Ambrosone C.B. , Hong C.C. , Lunetta K.L. , Liu S. , Hu Q. , Yao S. , Sucheston-Campbell L. , Bandera E.V. , Ruiz-Narváez E.A. , et al. .
Source: Carcinogenesis, 2016 Jan; 37(1), p. 49-55.
PMID: 26577839
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Gene-based analysis of the fibroblast growth factor receptor signaling pathway in relation to breast cancer in African American women: the AMBER consortium.
Authors: Ruiz-Narváez E.A. , Haddad S.A. , Lunetta K.L. , Yao S. , Bensen J.T. , Sucheston-Campbell L.E. , Hong C.C. , Haiman C.A. , Olshan A.F. , Ambrosone C.B. , et al. .
Source: Breast Cancer Research And Treatment, 2016 Jan; 155(2), p. 355-63.
PMID: 26743380
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Admixture Mapping Of African-american Women In The Amber Consortium Identifies New Loci For Breast Cancer And Estrogen-receptor Subtypes
Authors: Ruiz-Narváez E.A. , Sucheston-Campbell L. , Bensen J.T. , Yao S. , Haddad S. , Haiman C.A. , Bandera E.V. , John E.M. , Bernstein L. , Hu J.J. , et al. .
Source: Frontiers In Genetics, 2016; 7, p. 170.
PMID: 27708667
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Genetic Variation In The Insulin, Insulin-like Growth Factor, Growth Hormone, And Leptin Pathways In Relation To Breast Cancer In African-american Women: The Amber Consortium
Authors: Ruiz-Narváez E.A. , Lunetta K.L. , Hong C.C. , Haddad S. , Yao S. , Cheng T.D. , Bensen J.T. , Bandera E.V. , Haiman C.A. , Troester M.A. , et al. .
Source: Npj Breast Cancer, 2016; 2, .
PMID: 27942580
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Hormone-related Pathways And Risk Of Breast Cancer Subtypes In African American Women
Authors: Haddad S.A. , Lunetta K.L. , Ruiz-Narváez E.A. , Bensen J.T. , Hong C.C. , Sucheston-Campbell L.E. , Yao S. , Bandera E.V. , Rosenberg L. , Haiman C.A. , et al. .
Source: Breast Cancer Research And Treatment, 2015 Nov; 154(1), p. 145-54.
PMID: 26458823
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A comprehensive examination of breast cancer risk loci in African American women.
Authors: Feng Y. , Stram D.O. , Rhie S.K. , Millikan R.C. , Ambrosone C.B. , John E.M. , Bernstein L. , Zheng W. , Olshan A.F. , Hu J.J. , et al. .
Source: Human Molecular Genetics, 2014-10-15 00:00:00.0; 23(20), p. 5518-26.
EPub date: 2014-10-15 00:00:00.0.
PMID: 24852375
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Polymorphisms in vitamin D-related genes and risk of uterine leiomyomata.
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