||5R01CA132636-05 Interpret this number
||University Of Tx Md Anderson Can Ctr
||The Influence of HIV Disease Events/Stages on Smoking Attitudes and Behaviors
While mortality attributable to AIDS-related diseases has decreased dramatically in the
highly active antiretroviral therapy (HAART) era, the proportion of deaths attributable to
other diseases (e.g., cardiovascular disease, pulmonary disease, and cancer) has
markedly increased. Thus, efforts to reduce morbidity and mortality attributable to these
non-AIDS defining diseases represent an important public health priority. One approach
to improve health outcomes for this population is to target health-risk behaviors, such as
cigarette smoking. Existing evidence indicates that smoking prevalence is significantly
elevated among persons living with HIV/AIDS. In addition, smoking is associated with
numerous HIV-related adverse outcomes. Despite these findings, few efforts have been
made to deliver cessation treatment to this population. Also lacking are efforts to explore
the relationship between HIV disease events/stages and smoking. Thus, the overarching
goal of this project is to prospectively explore the relationship between HIV disease
events/stages, perceived impact of HIV, attitudes about smoking, and smoking
behaviors. HIV disease events/stages (e.g., time of HIV diagnosis, progressive disease,
and stable disease) will be evaluated as potential teachable moments for smoking
cessation. Specifically, we will identify and recruit newly HIV-diagnosed smokers from a
large, inner city HIV/AIDS care center serving a racially/ethnically diverse, medically
indigent population. Participants will complete a computer-administered assessment
designed to measure perceived impact of HIV, attitudes about smoking, and current
smoking behavior at the time of study enrollment. In addition to traditional self-report
measures, certain variables (e.g., perceived impact of HIV) will be assessed using
"implicit" cognitive psychological measures, as considerable evidence suggests that both
explicit and implicit measures yield unique information that predicts outcome.
Participants will be followed for one year and asked to complete follow-up computer-
administered assessments at three-month intervals. In addition to clinic administered
assessments, participants will complete brief weekly phone assessments that will allow
us to carefully track changes in perceived impact of disease and smoking behavior for
the first three months of follow-up. Research staff will also conduct medical record
reviews to document the timing and progression of disease (e.g., treatment failure,
diagnosis of an HIV- or non-HIV related disease). This design will enable us to carefully
track changes in smoking behavior over time, and to link these changes to both the
course of HIV-disease and/or to participants' perceived impact of HIV. By identifying
optimal time points for intervention, findings will have the potential to maximize the
efficiency and efficacy of cessation treatments delivered in resource-limited settings. In
addition, findings will be instrumental in identifying specific constructs that should be
targeted for intervention, and will provide a strong foundation for the development of
future cessation interventions targeting smokers living with HIV/AIDS. Project Narrative
The proposed study will provide important information about the relationship between HIV-disease
events/stages and smoking behavior among a low socio-economic status, racially/ethnically diverse
population. Specifically, findings will identify potential teachable moments for cessation interventions in the
course of HIV-disease, and will provide a strong foundation for the development of future cessation
interventions targeting this population.
Mediators Of A Smoking Cessation Intervention For Persons Living With Hiv/aids
, Kypriotakis G.
, Li L.
, Arduino R.C.
, Fletcher F.E.
, Tamí-Maury I.
, Gritz E.R.
Drug And Alcohol Dependence, 2015-02-01 00:00:00.0; 147, p. 76-80.
The Influence Of Hiv Disease Events/stages On Smoking Attitudes And Behaviors: Project State (study Of Tobacco Attitudes And Teachable Events)
, Fletcher F.E.
, Buchberg M.K.
, Li Y.
, Arduino R.C.
, Gritz E.R.
Bmc Public Health, 2014; 14, p. 149.
The Smoking Consequences Questionnaire: Factor structure and predictive validity among Spanish-speaking Latino smokers in the United States.
, Vidrine D.J.
, Costello T.J.
, Mazas C.
, Cofta-Woerpel L.
, Mejia L.M.
, Wetter D.W.
Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2009 Nov; 11(11), p. 1280-8.