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Grant Details

Grant Number: 5R01CA097893-06 Interpret this number
Primary Investigator: Gritz, Ellen
Organization: University Of Tx Md Anderson Can Ctr
Project Title: An Innovative Telephone Intervention for Hiv+ Smokers
Fiscal Year: 2011


Recent evidence suggests that the prevalence of cigarette smoking among individuals living with HIV/AIDS is dramatically higher than the prevalence in the general population. Given the association of smoking with numerous adverse HIV-related health outcomes (e.g., malignancies, cardiovascular disease, pulmonary infections, and oral diseases), innovative smoking cessation interventions targeting this growing population are greatly needed. The purpose of the proposed project is to compare two such interventions. A two-group randomized clinical trial will be used to compare smoking abstinence rates among a group (n=250) receiving a cellular phone intervention (CPI) to a group (n=250) receiving a recommended standard of care intervention (RSOC). All participants will be drawn from the low income, multiethnic patient population of a large inner city HIV/AIDS treatment center. The RSOC group will receive brief physician advice to quit, written materials, and a 10-week supply of nicotine replacement therapy (NRT) patches. This standard treatment approach is recommended in the Treating Tobacco Use and Dependence Clinical Practice Guideline and has been shown to be effective with other populations. The CPI group will receive 3-months of proactive smoking cessation counseling delivered via cellular telephone in addition to brief physician advice to quit, written materials, and NRT. Counseling session content of the CPI will be primarily drawn from cognitive-behavioral and motivational interviewing techniques. The primary outcome for this study will be point prevalence smoking abstinence 3-, 6-, and 12-months post scheduled quit day. The specific aims are to: 1) develop the CPI and compare it to a RSOC control group in a randomized clinical trial; and 2) evaluate the role of withdrawal, motivation, risk perception, self-efficacy, coping skills, social support, and negative affect as potential mediators of smoking abstinence. As a secondary exploratory aim, the cost- effectiveness of the two treatments, in terms of costs per treatment per smoker quit, will be compared.


The role of pain in quitting among human immunodeficiency virus (HIV)-positive smokers enrolled in a smoking cessation trial.
Authors: Aigner C.J. , Gritz E.R. , Tamí-Maury I. , Baum G.P. , Arduino R.C. , Vidrine D.J. .
Source: Substance abuse, 2017 Jul-Sep; 38(3), p. 249-252.
EPub date: 2017-02-08.
PMID: 28328303
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The role of BMI change on smoking abstinence in a sample of HIV-infected smokers.
Authors: Buchberg M.K. , Gritz E.R. , Kypriotakis G. , Arduino R.C. , Vidrine D.J. .
Source: AIDS care, 2016; 28(5), p. 603-7.
EPub date: 2015-12-15.
PMID: 26666313
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Mediators of a smoking cessation intervention for persons living with HIV/AIDS.
Authors: Vidrine D.J. , Kypriotakis G. , Li L. , Arduino R.C. , Fletcher F.E. , Tamí-Maury I. , Gritz E.R. .
Source: Drug and alcohol dependence, 2015-02-01; 147, p. 76-80.
EPub date: 2014-12-15.
PMID: 25542824
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Cervical cancer screening adherence among HIV-positive female smokers from a comprehensive HIV clinic.
Authors: Fletcher F.E. , Vidrine D.J. , Tami-Maury I. , Danysh H.E. , King R.M. , Buchberg M. , Arduino R.C. , Gritz E.R. .
Source: AIDS and behavior, 2014 Mar; 18(3), p. 544-54.
PMID: 23605155
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Poly-tobacco use among HIV-positive smokers: implications for smoking cessation efforts.
Authors: Tamí-Maury I. , Vidrine D.J. , Fletcher F.E. , Danysh H. , Arduino R. , Gritz E.R. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013 Dec; 15(12), p. 2100-6.
EPub date: 2013-08-01.
PMID: 23907506
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Long-term outcomes of a cell phone-delivered intervention for smokers living with HIV/AIDS.
Authors: Gritz E.R. , Danysh H.E. , Fletcher F.E. , Tami-Maury I. , Fingeret M.C. , King R.M. , Arduino R.C. , Vidrine D.J. .
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013 Aug; 57(4), p. 608-15.
EPub date: 2013-05-23.
PMID: 23704120
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Practice patterns and perceptions of thoracic oncology providers on tobacco use and cessation in cancer patients.
Authors: Warren G.W. , Marshall J.R. , Cummings K.M. , Toll B. , Gritz E.R. , Hutson A. , Dibaj S. , Herbst R. , Dresler C. , IASLC Tobacco Control and Smoking Cessation Committee .
Source: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013 May; 8(5), p. 543-8.
PMID: 23529191
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Tobacco assessment in actively accruing National Cancer Institute Cooperative Group Program Clinical Trials.
Authors: Peters E.N. , Torres E. , Toll B.A. , Cummings K.M. , Gritz E.R. , Hyland A. , Herbst R.S. , Marshall J.R. , Warren G.W. .
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012-08-10; 30(23), p. 2869-75.
EPub date: 2012-06-11.
PMID: 22689794
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Factors associated with nonadherence to antiretroviral therapy in HIV-positive smokers.
Authors: King R.M. , Vidrine D.J. , Danysh H.E. , Fletcher F.E. , McCurdy S. , Arduino R.C. , Gritz E.R. .
Source: AIDS patient care and STDs, 2012 Aug; 26(8), p. 479-85.
EPub date: 2012-05-21.
PMID: 22612468
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Efficacy of cell phone-delivered smoking cessation counseling for persons living with HIV/AIDS: 3-month outcomes.
Authors: Vidrine D.J. , Marks R.M. , Arduino R.C. , Gritz E.R. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2012 Jan; 14(1), p. 106-10.
EPub date: 2011-06-13.
PMID: 21669958
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The Smoking Consequences Questionnaire: Factor structure and predictive validity among Spanish-speaking Latino smokers in the United States.
Authors: Vidrine J.I. , Vidrine D.J. , Costello T.J. , Mazas C. , Cofta-Woerpel L. , Mejia L.M. , Wetter D.W. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2009 Nov; 11(11), p. 1280-8.
EPub date: 2009-08-20.
PMID: 19696309
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Tobacco dependence and withdrawal: science base, challenges and opportunities for pharmacotherapy.
Authors: Henningfield J.E. , Shiffman S. , Ferguson S.G. , Gritz E.R. .
Source: Pharmacology & therapeutics, 2009 Jul; 123(1), p. 1-16.
EPub date: 2009-04-08.
PMID: 19362108
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Cigarette smoking and HIV/AIDS: health implications, smoker characteristics and cessation strategies.
Authors: Vidrine D.J. .
Source: AIDS education and prevention : official publication of the International Society for AIDS Education, 2009 Jun; 21(3 Suppl), p. 3-13.
PMID: 19537950
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The association between body image and smoking cessation among individuals living with HIV/AIDS.
Authors: Fingeret M.C. , Vidrine D.J. , Arduino R.C. , Gritz E.R. .
Source: Body image, 2007 Jun; 4(2), p. 201-6.
EPub date: 2007-02-26.
PMID: 18089265
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Genetic association studies of cancer: where do we go from here?
Authors: Rebbeck T.R. , Khoury M.J. , Potter J.D. .
Source: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007 May; 16(5), p. 864-5.
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