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Grant Details

Grant Number: 5R01CA100254-05 Interpret this number
Primary Investigator: Hughes-Halbert, Chanita
Organization: University Of Pennsylvania
Project Title: Multi-Dimensional Cultural Values
Fiscal Year: 2009


DESCRIPTION (provided by applicant): Even though recent work has demonstrated that the disparity in cancer incidence and mortality is decreasing among members of ethnic and racial groups, African Americans and Hispanics continue to experience excess rates of cancer morbidity and mortality. Research is now being conducted to disentangle the effects of biological, behavioral, and sociocultural determinants of racial and ethnic disparities in cancer morbidity and mortality. Although understanding the role of cultural factors to cancer prevention and control behaviors has been the focus of much of this research, knowledge about the contribution of these factors to screening behaviors and avoidance of cancer risk factors has proceeded at slow rate because of the limited availability of reliable and valid methods for assessing these characteristics in ethnically and racially diverse populations. Culture is a multi-dimensional construct that includes beliefs and values; however, previous studies have focused on describing myths and folk beliefs about cancer among African Americans and Hispanics. This method of assessing cultural factors has had a limited impact on minimizing cancer disparities because myths and folk beliefs are not generalizable to all members of ethnic and racial groups. Methods for assessing cultural values related to cancer prevention and control that are reliable and valid for ethnically and racially diverse populations is needed to achieve the long-term objective of reducing and eliminating ethnic and racial disparities in cancer morbidity and mortality. Therefore, the specific aims of this study are to (1) develop a multi-dimensional cultural values assessment tool (MCVAT) that is sensitive to cultural values for cancer prevention and control among African Americans, Hispanics, and Caucasians; (2) evaluate the psychometric properties of the MCVAT among these diverse ethnic and racial groups; and (3) evaluate the construct, discriminant, and predictive validity of the instrument in these groups. Subjects eligible to participate in the study are African American, Caucasian, and Hispanic men and women ages 18-75. The study will be implemented in three phases. In Phase I we will conduct qualitative research to generate items for the MCVAT and in Phase II, we will conduct a cross-sectional survey study to evaluate the psychometric properties of the MCVAT. In Phase III, we will conduct a prospective, longitudinal survey study to evaluate the construct, discriminate, and predictive validity of the MCVAT. To accomplish these goals, we have assembled an investigative team of experts in culture, psychometrics, cancer prevention and control, and survey research. This study will provide a psychometrically sound instrument that can be used in clinical and research settings to provide culturally sensitive care and interventions to ethnically and racially diverse populations.


Discordance in perceived risk and epidemiological outcomes of prostate cancer among African American men.
Authors: Rice L.J. , Jefferson M. , Briggs V. , Delmoor E. , Johnson J.C. , Gattoni-Celli S. , Savage S.J. , Lilly M. , Prasad S.M. , Kittles R. , et al. .
Source: Preventive medicine reports, 2017 Sep; 7, p. 1-6.
EPub date: 2017-04-26.
PMID: 28507891
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Ever and Annual Use of Prostate Cancer Screening in African American Men.
Authors: Halbert C.H. , Gattoni-Celli S. , Savage S. , Prasad S.M. , Kittles R. , Briggs V. , Delmoor E. , Rice L.J. , Jefferson M. , Johnson J.C. .
Source: American journal of men's health, 2017 Jan; 11(1), p. 99-107.
EPub date: 2016-07-08.
PMID: 26240090
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Neighborhood Satisfaction and Colorectal Cancer Screening in a Community Sample of African Americans.
Authors: Halbert C.H. , Melvin C. , Briggs V. , Delmoor E. , Rice L.J. , Lynch C. , Jefferson M. , Johnson J.C. .
Source: Journal of community health, 2016 Feb; 41(1), p. 38-45.
PMID: 26184107
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Predictors of Participation in Mammography Screening among Non-Hispanic Black, Non-Hispanic White, and Hispanic Women.
Authors: Melvin C.L. , Jefferson M.S. , Rice L.J. , Cartmell K.B. , Halbert C.H. .
Source: Frontiers in public health, 2016; 4, p. 188.
EPub date: 2016-09-06.
PMID: 27656640
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B cells in chronic graft-versus-host disease.
Authors: Sarantopoulos S. , Blazar B.R. , Cutler C. , Ritz J. .
Source: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015 Jan; 21(1), p. 16-23.
EPub date: 2014-11-12.
PMID: 25452031
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Cultural, economic, and psychological predictors of colonoscopy in a national sample.
Authors: Halbert C.H. , Barg F.K. , Guerra C.E. , Shea J.A. , Armstrong K. , Ferguson M. , Weathers B. , Coyne J. , Troxel A.B. .
Source: Journal of general internal medicine, 2011 Nov; 26(11), p. 1311-6.
EPub date: 2011-07-06.
PMID: 21732197
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Racial differences in quality of life following prostate cancer diagnosis.
Authors: Halbert C.H. , Coyne J. , Weathers B. , Mahler B. , Delmoor E. , Vaughn D. , Malkowicz S.B. , Lee D. , Troxel A. .
Source: Urology, 2010 Sep; 76(3), p. 559-64.
EPub date: 2010-03-07.
PMID: 20207396
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Sociocultural determinants of men's reactions to prostate cancer diagnosis.
Authors: Halbert C.H. , Wrenn G. , Weathers B. , Delmoor E. , Ten Have T. , Coyne J.C. .
Source: Psycho-oncology, 2010 May; 19(5), p. 553-60.
PMID: 19408346
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Racial differences in medical mistrust among men diagnosed with prostate cancer.
Authors: Halbert C.H. , Weathers B. , Delmoor E. , Mahler B. , Coyne J. , Thompson H.S. , Have T.T. , Vaughn D. , Malkowicz S.B. , Lee D. .
Source: Cancer, 2009-06-01; 115(11), p. 2553-61.
PMID: 19296516
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Differences in cultural beliefs and values among African American and European American men with prostate cancer.
Authors: Hughes Halbert C. , Barg F.K. , Weathers B. , Delmoor E. , Coyne J. , Wileyto E.P. , Arocho J. , Mahler B. , Malkowicz S.B. .
Source: Cancer control : journal of the Moffitt Cancer Center, 2007 Jul; 14(3), p. 277-84.
PMID: 17615534
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Sociocultural predictors of breast cancer risk perceptions in African American breast cancer survivors.
Authors: Brewster K. , Wileyto E.P. , Kessler L. , Collier A. , Weathers B. , Stopfer J.E. , Domchek S. , Halbert C.H. .
Source: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007 Feb; 16(2), p. 244-8.
PMID: 17301256
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