Grant Number:	2R01CA092153-06 Interpret this number
Primary Investigator:	Cerhan, James
Organization:	Mayo Clinic Rochester
Project Title:	Molecular Epidemiology of Nhl and Cll
Fiscal Year:	2008

DESCRIPTION (provided by applicant): Non-Hodgkin lymphoma (NHL) is now the 5th most frequently diagnosed cancer among both men and women in the US. There is rapidly accumulating evidence for several candidate susceptibility genes in the etiology of NHL, supporting a polygenic model based on low-penetrance alleles in line with the common-variant, common- disease hypothesis. In parallel, much progress has been made in uncovering environmental risk factors for this cancer, and the field is maturing to the point of beginning to evaluate gene-environment interactions. This application is a request for renewal of R01 CA92153 to allow us to continue our investigation into the etiology of this important cancer. We have made major progress on the scientific and operational goals from the original grant. The goal of this renewal is to increase our understanding of the genetic and environmental etiology of NHL by building on several key leads from the last grant cycle. There are four specific aims: 1) To evaluate the association of inherited variability in inflammation and immune genes with risk of NHL; 2) To evaluate epidemiologic risk factors for NHL, with a focus on medical history (including aspirin and NSAID use, immunization history, and statin use), energy balance (including obesity and physical activity), diet (including antioxidant-related nutrients and flavonoids), and farming/pesticide exposure (including farm practices and exposure to phenoxyacetic acid and triazine herbicides and organophosphate insecticides); 3) To evaluate gene-environment interactions in the etiology of NHL, with a focus on the interaction of immune-related genes with immunologic diseases/conditions and the interaction of genes involved in carcinogen metabolism and detoxification pathways with antioxidant-related dietary factors; and 4) To validate selected genetic and epidemiologic risk factor findings from this renewal in the InterLymph Consortium, including the top 20 single nucleotide polymorphisms (SNPs) from Aim 1. To achieve these aims, we will utilize our ongoing, clinic-based case-control study of NHL. Through April 2007, we have enrolled 940 NHL cases and 1,197 controls, and by the completion of this renewal application, we will have an estimated 2,000 NHL cases and 2,000 controls. We have built an outstanding resource, with central phenotypic definition by expert hematopathologists, extensive collection of biologic samples and risk factor data, access to state-of-the-art bioinformatics and genotyping, and an established, interdisciplinary study team. In this renewal, we will have excellent power to test our a priori hypotheses, and we will use a two-stage design for our genetic studies to increase efficiency. We are fully engaged in the InterLymph Consortium by contributing data for pooled studies, as well as taking leadership roles in several initiatives. The pooling activities of the consortium are critical for replication in large, independent samples, in order to more rapidly advance the field and to adequately address hypotheses related to NHL subtypes. Completion of the renewal aims will significantly advance our understanding of the etiology of this cancer, and should help identify new approaches for the prevention and control of NHL. PUBLIC HEALTH RELEVANCE: Non-Hodgkin lymphoma (NHL) is an important cancer in the United States, and we only partially understand the genetic and environmental risk factors for this malignancy. We will build off the progress from the previous funding period, and completion of our renewal aims will significantly advance our understanding of the etiology of this cancer, and should help identify new approaches for the prevention and control of NHL.




Blood Plasma Methylated DNA Markers in the Detection of Lymphoma: Discovery, Validation, and Clinical Pilot.
Authors: Witzig T.E. , Taylor W.R. , Mahoney D.W. , Bamlet W.R. , Foote P.H. , Burger K.N. , Doering K.A. , Devens M.E. , Arndt J.R. , O'Connell M.C. , et al. .
Source: American Journal Of Hematology, 2024-11-20 00:00:00.0; , .
EPub date: 2024-11-20 00:00:00.0.
PMID: 39564730
Related Citations

Herbicide use in farming and other jobs in relation to non-Hodgkin's lymphoma (NHL) risk.
Authors: De Roos A.J. , Fritschi L. , Ward M.H. , Monnereau A. , Hofmann J. , Bernstein L. , Bhatti P. , Benavente Moreno Y. , Benke G. , Casabonne D. , et al. .
Source: Occupational And Environmental Medicine, 2022 Dec; 79(12), p. 795-806.
EPub date: 2022-10-07 00:00:00.0.
PMID: 36207110
Related Citations

B-Cell NHL Subtype Risk Associated with Autoimmune Conditions and PRS.
Authors: Wang S.S. , Vajdic C.M. , Linet M.S. , Slager S.L. , Voutsinas J. , Nieters A. , Casabonne D. , Cerhan J.R. , Cozen W. , Alarcón G. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2022-05-04 00:00:00.0; 31(5), p. 1103-1110.
PMID: 35244686
Related Citations

Vaccination History and Risk of Lymphoma and Its Major Subtypes.
Authors: Kleinstern G. , Larson M.C. , Ansell S.M. , Thompson C.A. , Nowakowski G.S. , Call T.G. , Robinson D.P. , Maurer M.J. , Mwangi R. , Feldman A.L. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2022 Feb; 31(2), p. 461-470.
EPub date: 2021-11-15 00:00:00.0.
PMID: 34782394
Related Citations

Occupational insecticide exposure and risk of non-Hodgkin lymphoma: A pooled case-control study from the InterLymph Consortium.
Authors: De Roos A.J. , Schinasi L.H. , Miligi L. , Cerhan J.R. , Bhatti P. , 't Mannetje A. , Baris D. , Benavente Y. , Benke G. , Clavel J. , et al. .
Source: International Journal Of Cancer, 2021-07-16 00:00:00.0; , .
EPub date: 2021-07-16 00:00:00.0.
PMID: 34270795
Related Citations

Aspirin and other nonsteroidal anti-inflammatory drugs, statins and risk of non-Hodgkin lymphoma.
Authors: Liebow M. , Larson M.C. , Thompson C.A. , Nowakowski G.S. , Call T.G. , Macon W.R. , Kay N.E. , Habermann T.M. , Slager S.L. , Cerhan J.R. .
Source: International Journal Of Cancer, 2021-02-28 00:00:00.0; , .
EPub date: 2021-02-28 00:00:00.0.
PMID: 33644854
Related Citations

Genome-wide homozygosity and risk of four non-Hodgkin lymphoma subtypes.
Authors: Moore A. , Machiela M.J. , Machado M. , Wang S.S. , Kane E. , Slager S.L. , Zhou W. , Carrington M. , Lan Q. , Milne R.L. , et al. .
Source: Journal Of Translational Genetics And Genomics, 2021; 5, p. 200-217.
EPub date: 2021-06-17 00:00:00.0.
PMID: 34622145
Related Citations

Delineation of clinical and biological factors associated with cutaneous squamous cell carcinoma among patients with chronic lymphocytic leukemia.
Authors: Kleinstern G. , Rishi A. , Achenbach S.J. , Rabe K.G. , Kay N.E. , Shanafelt T.D. , Ding W. , Leis J.F. , Norman A.D. , Call T.G. , et al. .
Source: Journal Of The American Academy Of Dermatology, 2020-07-16 00:00:00.0; , .
EPub date: 2020-07-16 00:00:00.0.
PMID: 32682027
Related Citations

Lipid Trait Variants and the Risk of Non-Hodgkin Lymphoma Subtypes: A Mendelian Randomization Study.
Authors: Kleinstern G. , Camp N.J. , Berndt S.I. , Birmann B.M. , Nieters A. , Bracci P.M. , McKay J.D. , Ghesquières H. , Lan Q. , Hjalgrim H. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2020 May; 29(5), p. 1074-1078.
EPub date: 2020-02-27 00:00:00.0.
PMID: 32108027
Related Citations

Genome-wide Association Study Identifies HLA-DPB1 as a Significant Risk Factor for Severe Aplastic Anemia.
Authors: Savage S.A. , Viard M. , O'hUigin C. , Zhou W. , Yeager M. , Li S.A. , Wang T. , Ramsuran V. , Vince N. , Vogt A. , et al. .
Source: American Journal Of Human Genetics, 2020-02-06 00:00:00.0; 106(2), p. 264-271.
EPub date: 2020-01-30 00:00:00.0.
PMID: 32004448
Related Citations

Genetic overlap between autoimmune diseases and non-Hodgkin lymphoma subtypes.
Authors: Din L. , Sheikh M. , Kosaraju N. , Smedby K.E. , Bernatsky S. , Berndt S.I. , Skibola C.F. , Nieters A. , Wang S. , McKay J.D. , et al. .
Source: Genetic Epidemiology, 2019-08-13 00:00:00.0; , .
EPub date: 2019-08-13 00:00:00.0.
PMID: 31407831
Related Citations

Association of elevated serumfree light chains with chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.
Authors: Clay-Gilmour A.I. , Rishi A.R. , Goldin L.R. , Greenberg-Worisek A.J. , Achenbach S.J. , Rabe K.G. , Maurer M.J. , Kay N.E. , Shanafelt T.D. , Call T.G. , et al. .
Source: Blood Cancer Journal, 2019-08-05 00:00:00.0; 9(8), p. 59.
EPub date: 2019-08-05 00:00:00.0.
PMID: 31383849
Related Citations

Blood transfusion history and risk of non-Hodgkin lymphoma: an InterLymph pooled analysis.
Authors: Cerhan J.R. , Kane E. , Vajdic C.M. , Linet M.S. , Monnereau A. , Bernstein L. , de Sanjose S. , Chiu B.C. , Spinelli J.J. , Maso L.D. , et al. .
Source: Cancer Causes & Control : Ccc, 2019 Aug; 30(8), p. 889-900.
EPub date: 2019-06-04 00:00:00.0.
PMID: 31165419
Related Citations

HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes.
Authors: Wang S.S. , Carrington M. , Berndt S.I. , Slager S.L. , Bracci P.M. , Voutsinas J. , Cerhan J.R. , Smedby K.E. , Hjalgrim H. , Vijai J. , et al. .
Source: Cancer Research, 2018-07-15 00:00:00.0; 78(14), p. 4086-4096.
EPub date: 2018-05-07 00:00:00.0.
PMID: 29735552
Related Citations

Association of polygenic risk score with the risk of chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis.
Authors: Kleinstern G. , Camp N.J. , Goldin L.R. , Vachon C.M. , Vajdic C.M. , de Sanjose S. , Weinberg J.B. , Benavente Y. , Casabonne D. , Liebow M. , et al. .
Source: Blood, 2018-06-07 00:00:00.0; 131(23), p. 2541-2551.
EPub date: 2018-04-19 00:00:00.0.
PMID: 29674426
Related Citations

Human Pegivirus infection and lymphoma risk and prognosis: a North American study.
Authors: Fama A. , Xiang J. , Link B.K. , Allmer C. , Klinzman D. , Feldman A.L. , Nowakowski G.S. , Liebow M. , Larson M.C. , Maurer M.J. , et al. .
Source: British Journal Of Haematology, 2018-05-29 00:00:00.0; , .
EPub date: 2018-05-29 00:00:00.0.
PMID: 29808922
Related Citations

Cohort Profile: The Lymphoma Specialized Program of Research Excellence (SPORE) Molecular Epidemiology Resource (MER) Cohort Study.
Authors: Cerhan J.R. , Link B.K. , Habermann T.M. , Maurer M.J. , Feldman A.L. , Syrbu S.I. , Thompson C.A. , Farooq U. , Novak A.J. , Slager S.L. , et al. .
Source: International Journal Of Epidemiology, 2017-12-01 00:00:00.0; 46(6), p. 1753-1754i.
PMID: 29025017
Related Citations

Soluble programmed death-ligand 1 as a prognostic biomarker for overall survival in patients with diffuse large B-cell lymphoma: a replication study and combined analysis of 508 patients.
Authors: Rossille D. , Azzaoui I. , Feldman A.L. , Maurer M.J. , Labouré G. , Parrens M. , Pangault C. , Habermann T.M. , Ansell S.M. , Link B.K. , et al. .
Source: Leukemia, 2017 Apr; 31(4), p. 988-991.
EPub date: 2017-01-27 00:00:00.0.
PMID: 28035137
Related Citations

Genome-wide Association Analysis Implicates Dysregulation Of Immunity Genes In Chronic Lymphocytic Leukaemia
Authors: Law P.J. , Berndt S.I. , Speedy H.E. , Camp N.J. , Sava G.P. , Skibola C.F. , Holroyd A. , Joseph V. , Sunter N.J. , Nieters A. , et al. .
Source: Nature Communications, 2017-02-06 00:00:00.0; 8, p. 14175.
PMID: 28165464
Related Citations

Genetically predicted longer telomere length is associated with increased risk of B-cell lymphoma subtypes.
Authors: Machiela M.J. , Lan Q. , Slager S.L. , Vermeulen R.C. , Teras L.R. , Camp N.J. , Cerhan J.R. , Spinelli J.J. , Wang S.S. , Nieters A. , et al. .
Source: Human Molecular Genetics, 2016-04-15 00:00:00.0; 25(8), p. 1663-76.
EPub date: 2016-04-15 00:00:00.0.
PMID: 27008888
Related Citations

Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia.
Authors: Berndt S.I. , Camp N.J. , Skibola C.F. , Vijai J. , Wang Z. , Gu J. , Nieters A. , Kelly R.S. , Smedby K.E. , Monnereau A. , et al. .
Source: Nature Communications, 2016-03-09 00:00:00.0; 7, p. 10933.
EPub date: 2016-03-09 00:00:00.0.
PMID: 26956414
Related Citations

Risk Of Non-hematologic Cancer In Individuals With High-count Monoclonal B-cell Lymphocytosis
Authors: Solomon B.M. , Chaffee K.G. , Moreira J. , Schwager S.M. , Cerhan J.R. , Call T.G. , Kay N.E. , Slager S.L. , Shanafelt T.D. .
Source: Leukemia, 2016 Feb; 30(2), p. 331-6.
PMID: 26310541
Related Citations

Comprehensive Serum Cytokine Analysis Identifies Il-1ra And Soluble Il-2r¿ As Predictors Of Event-free Survival In T-cell Lymphoma
Authors: Gupta M. , Stenson M. , O'Byrne M. , Maurer M.J. , Habermann T. , Cerhan J.R. , Weiner G.W. , Witzig T.E. .
Source: Annals Of Oncology : Official Journal Of The European Society For Medical Oncology / Esmo, 2016 Jan; 27(1), p. 165-72.
PMID: 26487586
Related Citations

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.
Authors: Sampson J.N. , Wheeler W.A. , Yeager M. , Panagiotou O. , Wang Z. , Berndt S.I. , Lan Q. , Abnet C.C. , Amundadottir L.T. , Figueroa J.D. , et al. .
Source: Journal Of The National Cancer Institute, 2015 Dec; 107(12), p. djv279.
PMID: 26464424
Related Citations

Familial Predisposition And Genetic Risk Factors For Lymphoma
Authors: Cerhan J.R. , Slager S.L. .
Source: Blood, 2015-11-12 00:00:00.0; 126(20), p. 2265-73.
PMID: 26405224
Related Citations

Non-hodgkin Lymphoma, Body Mass Index, And Cytokine Polymorphisms: A Pooled Analysis From The Interlymph Consortium
Authors: Kane E. , Skibola C.F. , Bracci P.M. , Cerhan J.R. , Costas L. , Smedby K.E. , Holly E.A. , Maynadié M. , Novak A.J. , Lightfoot T.J. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2015 Jul; 24(7), p. 1061-70.
PMID: 25962811
Related Citations

The Oncogenic Transcription Factor Irf4 Is Regulated By A Novel Cd30/nf-¿b Positive Feedback Loop In Peripheral T-cell Lymphoma
Authors: Boddicker R.L. , Kip N.S. , Xing X. , Zeng Y. , Yang Z.Z. , Lee J.H. , Almada L.L. , Elsawa S.F. , Knudson R.A. , Law M.E. , et al. .
Source: Blood, 2015-05-14 00:00:00.0; 125(20), p. 3118-27.
PMID: 25833963
Related Citations

Associations of non-Hodgkin Lymphoma (NHL) risk with autoimmune conditions according to putative NHL loci.
Authors: Wang S.S. , Vajdic C.M. , Linet M.S. , Slager S.L. , Voutsinas J. , Nieters A. , de Sanjose S. , Cozen W. , Alarcón G.S. , Martinez-Maza O. , et al. .
Source: American Journal Of Epidemiology, 2015-03-15 00:00:00.0; 181(6), p. 406-21.
EPub date: 2015-03-15 00:00:00.0.
PMID: 25713336
Related Citations

A genome-wide association study of marginal zone lymphoma shows association to the HLA region.
Authors: Vijai J. , Wang Z. , Berndt S.I. , Skibola C.F. , Slager S.L. , de Sanjose S. , Melbye M. , Glimelius B. , Bracci P.M. , Conde L. , et al. .
Source: Nature Communications, 2015-01-08 00:00:00.0; 6, p. 5751.
EPub date: 2015-01-08 00:00:00.0.
PMID: 25569183
Related Citations

The Association Of Copy Number Variation And Percent Mammographic Density
Authors: Atkinson E.J. , Eckel-Passow J.E. , Wang A. , Greenberg A.J. , Scott C.G. , Pankratz V.S. , Purrington K.N. , Sellers T.A. , Rider D.N. , Heit J.A. , et al. .
Source: Bmc Research Notes, 2015; 8, p. 297.
PMID: 26152678
Related Citations

Elevated Soluble Il-2r¿, Il-8, And Mip-1ß Levels Are Associated With Inferior Outcome And Are Independent Of Mipi Score In Patients With Mantle Cell Lymphoma
Authors: Sonbol M.B. , Maurer M.J. , Stenson M.J. , Allmer C. , LaPlant B.R. , Weiner G.J. , Macon W.R. , Cerhan J.R. , Witzig T.E. , Gupta M. .
Source: American Journal Of Hematology, 2014 Dec; 89(12), p. E223-7.
PMID: 25164110
Related Citations

Genome-wide association study identifies multiple susceptibility loci for diffuse large B cell lymphoma.
Authors: Cerhan J.R. , Berndt S.I. , Vijai J. , Ghesquières H. , McKay J. , Wang S.S. , Wang Z. , Yeager M. , Conde L. , de Bakker P.I. , et al. .
Source: Nature Genetics, 2014 Nov; 46(11), p. 1233-8.
PMID: 25261932
Related Citations

Rationale and Design of the International Lymphoma Epidemiology Consortium (InterLymph) Non-Hodgkin Lymphoma Subtypes Project.
Authors: Morton L.M. , Sampson J.N. , Cerhan J.R. , Turner J.J. , Vajdic C.M. , Wang S.S. , Smedby K.E. , de Sanjosé S. , Monnereau A. , Benavente Y. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 1-14.
PMID: 25174022
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for diffuse large B-cell lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Cerhan J.R. , Kricker A. , Paltiel O. , Flowers C.R. , Wang S.S. , Monnereau A. , Blair A. , Dal Maso L. , Kane E.V. , Nieters A. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 15-25.
PMID: 25174023
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for follicular lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Linet M.S. , Vajdic C.M. , Morton L.M. , de Roos A.J. , Skibola C.F. , Boffetta P. , Cerhan J.R. , Flowers C.R. , de Sanjosé S. , Monnereau A. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 26-40.
PMID: 25174024
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for chronic lymphocytic leukemia/small lymphocytic lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Slager S.L. , Benavente Y. , Blair A. , Vermeulen R. , Cerhan J.R. , Costantini A.S. , Monnereau A. , Nieters A. , Clavel J. , Call T.G. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 41-51.
PMID: 25174025
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for marginal zone lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Bracci P.M. , Benavente Y. , Turner J.J. , Paltiel O. , Slager S.L. , Vajdic C.M. , Norman A.D. , Cerhan J.R. , Chiu B.C. , Becker N. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 52-65.
PMID: 25174026
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for peripheral T-cell lymphomas: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Wang S.S. , Flowers C.R. , Kadin M.E. , Chang E.T. , Hughes A.M. , Ansell S.M. , Feldman A.L. , Lightfoot T. , Boffetta P. , Melbye M. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 66-75.
PMID: 25174027
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for mantle cell lymphoma: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Smedby K.E. , Sampson J.N. , Turner J.J. , Slager S.L. , Maynadié M. , Roman E. , Habermann T.M. , Flowers C.R. , Berndt S.I. , Bracci P.M. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 76-86.
PMID: 25174028
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for lymphoplasmacytic lymphoma/Waldenström's macroglobulinemia: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Vajdic C.M. , Landgren O. , McMaster M.L. , Slager S.L. , Brooks-Wilson A. , Smith A. , Staines A. , Dogan A. , Ansell S.M. , Sampson J.N. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 87-97.
PMID: 25174029
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for mycosis fungoides and Sézary syndrome: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Aschebrook-Kilfoy B. , Cocco P. , La Vecchia C. , Chang E.T. , Vajdic C.M. , Kadin M.E. , Spinelli J.J. , Morton L.M. , Kane E.V. , Sampson J.N. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 98-105.
PMID: 25174030
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for sporadic Burkitt lymphoma/leukemia: the Interlymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Mbulaiteye S.M. , Morton L.M. , Sampson J.N. , Chang E.T. , Costas L. , de Sanjosé S. , Lightfoot T. , Kelly J. , Friedberg J.W. , Cozen W. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 106-14.
PMID: 25174031
Related Citations

Medical history, lifestyle, and occupational risk factors for hairy cell leukemia: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Monnereau A. , Slager S.L. , Hughes A.M. , Smith A. , Glimelius B. , Habermann T.M. , Berndt S.I. , Staines A. , Norman A.D. , Cerhan J.R. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 115-24.
PMID: 25174032
Related Citations

Medical history, lifestyle, family history, and occupational risk factors for adult acute lymphocytic leukemia: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Skibola C.F. , Slager S.L. , Berndt S.I. , Lightfoot T. , Sampson J.N. , Morton L.M. , Weisenburger D.D. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 125-9.
PMID: 25174033
Related Citations

Etiologic heterogeneity among non-Hodgkin lymphoma subtypes: the InterLymph Non-Hodgkin Lymphoma Subtypes Project.
Authors: Morton L.M. , Slager S.L. , Cerhan J.R. , Wang S.S. , Vajdic C.M. , Skibola C.F. , Bracci P.M. , de Sanjosé S. , Smedby K.E. , Chiu B.C. , et al. .
Source: Journal Of The National Cancer Institute. Monographs, 2014 Aug; 2014(48), p. 130-44.
PMID: 25174034
Related Citations

A meta-analysis of Hodgkin lymphoma reveals 19p13.3 TCF3 as a novel susceptibility locus.
Authors: Cozen W. , Timofeeva M.N. , Li D. , Diepstra A. , Hazelett D. , Delahaye-Sourdeix M. , Edlund C.K. , Franke L. , Rostgaard K. , Van Den Berg D.J. , et al. .
Source: Nature Communications, 2014-06-12 00:00:00.0; 5, p. 3856.
EPub date: 2014-06-12 00:00:00.0.
PMID: 24920014
Related Citations

Cytokine Gene Polymorphisms And Progression-free Survival In Classical Hodgkin Lymphoma By Ebv Status: Results From Two Independent Cohorts
Authors: Ghesquières H. , Maurer M.J. , Casasnovas O. , Ansell S.M. , Larrabee B.R. , Lech-Maranda E. , Novak A.J. , Borrel A.L. , Slager S.L. , Brice P. , et al. .
Source: Cytokine, 2013 Nov; 64(2), p. 523-31.
PMID: 24008079
Related Citations

Genetic Susceptibility To Chronic Lymphocytic Leukemia
Authors: Slager S.L. , Caporaso N.E. , de Sanjose S. , Goldin L.R. .
Source: Seminars In Hematology, 2013 Oct; 50(4), p. 296-302.
PMID: 24246697
Related Citations

CXCR5 polymorphisms in non-Hodgkin lymphoma risk and prognosis.
Authors: Charbonneau B. , Wang A.H. , Maurer M.J. , Asmann Y.W. , Zent C.S. , Link B.K. , Ansell S.M. , Weiner G.J. , Ozsan N. , Feldman A.L. , et al. .
Source: Cancer Immunology, Immunotherapy : Cii, 2013 Sep; 62(9), p. 1475-84.
PMID: 23812490
Related Citations

Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia.
Authors: Berndt S.I. , Skibola C.F. , Joseph V. , Camp N.J. , Nieters A. , Wang Z. , Cozen W. , Monnereau A. , Wang S.S. , Kelly R.S. , et al. .
Source: Nature Genetics, 2013 Aug; 45(8), p. 868-76.
PMID: 23770605
Related Citations