Grant Number:	1R43CA132347-01 Interpret this number
Primary Investigator:	Goovaerts, Pierre
Organization:	Biomedware
Project Title:	Geostatistical Software for the Analysis of Individual-Level Epidemiologic Data
Fiscal Year:	2007

DESCRIPTION (provided by applicant): The overall objective of this project is to develop the first GIS-based software to offer tools that are specifically designed for the geostatistical analysis of both aggregated and individual-level health data, providing: description of spatial patterns of cancer incidence and mortality rates and identification of scales of variability, spatial interpolation of individual-level data to create isopleth maps of relative risk, identification of clusters and hotspots of significantly high or low incidence or mortality rates, detection of significant discrepancies between health outcomes for different ethnic or racial groups (health disparities), and visualization of changes in disparity through time. This product will allow the investigation of geographic and ethnic variations in cancer stage at diagnosis and survival data, and the exploration of relationships between health outcomes and potential factors, such as environmental and occupational exposures, socio-economic conditions, proximity to screening centers, leading to: (1) a better understanding of the causes underlying observed geographic and racial disparities in cancer incidence, mortality and survival, and (2) long-term quantification of the benefits of current strategies for reducing the disproportionate incidence of cancer morbidity and mortality among minorities and the medically underserved in the United States. Instructional materials will be developed to promote the use of this relatively new methodology among health scientists. Phase I of the project will: risk maps from individual-level data and statistical tests to detect significant differences in cancer rates among sub-populations and across space. into the software: TerraSeer Space-Time Intelligence System(tm) (STIS(tm)). geographical and racial disparities. The substantial benefit of this research is its utility in accessing, linking, mapping and analyzing diverse population-based and individual-level data including cancer vital events and measures of socioeconomic, demographic, behavioral and environmental conditions. The methods developed in this project will help understanding the causes underlying the disparities in cancer incidence, mortality and morbidity observed across space and among sub-populations, as well as lead to a better assessment of the benefits of current strategies for reducing these disparities.




Comparison of Soft Indicator and Poisson Kriging for the Noise-Filtering and Downscaling of Areal Data: Application to Daily COVID-19 Incidence Rates.
Authors: Goovaerts P. , Hermans T. , Goossens P.F. , Van De Vijver E. .
Source: Isprs International Journal Of Geo-information, 2023 Aug; 12(8), .
EPub date: 2023-08-05 00:00:00.0.
PMID: 38846757
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Impact Of Age, Race And Socio-economic Status On Temporal Trends In Late-stage Prostate Cancer Diagnosis In Florida
Authors: Goovaerts P. , Xiao H. , Gwede C.K. , Tan F. , Huang Y. , Adunlin G. , Ali A. .
Source: Spatial Statistics, 2015-11-01 00:00:00.0; 14(Pt 100), p. 321-337.
PMID: 26644992
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GEOGRAPHICALLY-WEIGHTED REGRESSION ANALYSIS OF PERCENTAGE OF LATE-STAGE PROSTATE CANCER DIAGNOSIS IN FLORIDA.
Authors: Goovaerts P. , Xiao H. , Adunlin G. , Ali A. , Tan F. , Gwede C.K. , Huang Y. .
Source: Applied Geography (sevenoaks, England), 2015-08-01 00:00:00.0; 62, p. 191-200.
PMID: 26257450
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Analysis of geographical disparities in temporal trends of health outcomes using space-time joinpoint regression.
Authors: Goovaerts P. .
Source: International Journal Of Applied Earth Observation And Geoinformation : Itc Journal, 2013 Jun; 22, p. 75-85.
PMID: 23710162
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A comparison of multiple indicator kriging and area-to-point Poisson kriging for mapping patterns of herbivore species abundance in Kruger National Park, South Africa.
Authors: Kerry R. , Goovaerts P. , Smit I.P. , Ingram B.R. .
Source: International Journal Of Geographical Information Science : Ijgis, 2013; 27(1), p. 47-67.
PMID: 25729318
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The impact of place and time on the proportion of late-stage diagnosis: the case of prostate cancer in Florida, 1981-2007.
Authors: Goovaerts P. , Xiao H. .
Source: Spatial And Spatio-temporal Epidemiology, 2012 Sep; 3(3), p. 243-53.
PMID: 22749210
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Identifying risk factors for disparities in breast cancer mortality among African-American and Hispanic women.
Authors: Tian N. , Goovaerts P. , Zhan F.B. , Chow T.E. , Wilson J.G. .
Source: Women's Health Issues : Official Publication Of The Jacobs Institute Of Women's Health, 2012 May-Jun; 22(3), p. e267-76.
PMID: 22265181
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Geostatistical analysis of health data with different levels of spatial aggregation.
Authors: Goovaerts P. .
Source: Spatial And Spatio-temporal Epidemiology, 2012 Apr; 3(1), p. 83-92.
PMID: 22469493
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Inequality in Human Resources for Health: Measurement Issues.
Authors: Speybroeck N. , Paraje G. , Prasad A. , Goovaerts P. , Ebener S. , Evans D.B. .
Source: Geographical Analysis, 2012-04-01 00:00:00.0; 44(2), p. 151-161.
EPub date: 2012-04-01 00:00:00.0.
PMID: 22736806
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Disaggregation of legacy soil data using area to point kriging for mapping soil organic carbon at the regional scale.
Authors: Kerry R. , Goovaerts P. , Rawlins B.G. , Marchant B.P. .
Source: Geoderma, 2012-01-15 00:00:00.0; 170, p. 347-358.
PMID: 25729090
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Geographical, temporal and racial disparities in late-stage prostate cancer incidence across Florida: a multiscale joinpoint regression analysis.
Authors: Goovaerts P. , Xiao H. .
Source: International Journal Of Health Geographics, 2011-12-05 00:00:00.0; 10, p. 63.
EPub date: 2011-12-05 00:00:00.0.
PMID: 22142274
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A coherent geostatistical approach for combining choropleth map and field data in the spatial interpolation of soil properties.
Authors: Goovaerts P. .
Source: European Journal Of Soil Science, 2011 Jun; 62(3), p. 371-380.
PMID: 22308075
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Racial and geographic disparities in late-stage prostate cancer diagnosis in Florida.
Authors: Xiao H. , Tan F. , Goovaerts P. .
Source: Journal Of Health Care For The Poor And Underserved, 2011; 22(4 Suppl), p. 187-99.
PMID: 22102314
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Incorporating individual-level distributions of exposure error in epidemiologic analyses: an example using arsenic in drinking water and bladder cancer.
Authors: Meliker J.R. , Goovaerts P. , Jacquez G.M. , Nriagu J.O. .
Source: Annals Of Epidemiology, 2010 Oct; 20(10), p. 750-8.
PMID: 20816314
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Identification of racial disparities in breast cancer mortality: does scale matter?
Authors: Tian N. , Goovaerts P. , Zhan F.B. , Wilson J.G. .
Source: International Journal Of Health Geographics, 2010-07-05 00:00:00.0; 9, p. 35.
EPub date: 2010-07-05 00:00:00.0.
PMID: 20602784
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Combining Areal and Point Data in Geostatistical Interpolation: Applications to Soil Science and Medical Geography.
Authors: Goovaerts P. .
Source: Mathematical Geosciences, 2010-07-01 00:00:00.0; 42(5), p. 535-554.
PMID: 21132098
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Visualizing and testing the impact of place on late-stage breast cancer incidence: a non-parametric geostatistical approach.
Authors: Goovaerts P. .
Source: Health & Place, 2010 Mar; 16(2), p. 321-30.
PMID: 19959392
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Geostatistical Analysis of County-Level Lung Cancer Mortality Rates in the Southeastern United States.
Authors: Goovaerts P. .
Source: Geographical Analysis, 2010-01-01 00:00:00.0; 42(1), p. 32-52.
PMID: 20445829
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Applying Geostatistical Analysis to Crime Data: Car-Related Thefts in the Baltic States.
Authors: Kerry R. , Goovaerts P. , Haining R.P. , Ceccato V. .
Source: Geographical Analysis, 2010 Jan; 42(1), p. 53-77.
PMID: 22190762
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Combining area-based and individual-level data in the geostatistical mapping of late-stage cancer incidence.
Authors: Goovaerts P. .
Source: Spatial And Spatio-temporal Epidemiology, 2009 Oct-Dec; 1(1), p. 61-71.
PMID: 20300557
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Spatial cluster analysis of early stage breast cancer: a method for public health practice using cancer registry data.
Authors: Meliker J.R. , Jacquez G.M. , Goovaerts P. , Copeland G. , Yassine M. .
Source: Cancer Causes & Control : Ccc, 2009 Sep; 20(7), p. 1061-9.
PMID: 19219634
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AUTO-IK: a 2D indicator kriging program for the automated non-parametric modeling of local uncertainty in earth sciences.
Authors: Goovaerts P. .
Source: Computers & Geosciences, 2009 Jun; 35(6), p. 1255-1270.
PMID: 20161335
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Medical Geography: a Promising Field of Application for Geostatistics.
Authors: Goovaerts P. .
Source: Mathematical Geology, 2009; 41, p. 243-264.
PMID: 19412347
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