Grant Details
Grant Number: |
3U24CA078146-05S4 Interpret this number |
Primary Investigator: |
Isaacs, Claudine |
Organization: |
Georgetown University |
Project Title: |
Cancer Genetics Network |
Fiscal Year: |
2006 |
Abstract
DESCRIPTION: (Applicant's Description) While advances in cancer genetics
are occurring at rapid pace, critical questions about genetic susceptibility
and prevention remain unanswered. In response to the RFA for the Cancer
Genetics Network, we propose to: (1) Enroll substantial numbers of the
following populations into the CGN: (a) hereditary breast, ovarian, and
colon cancer families, (b) newly diagnosed high risk breast cancer patients,
and (c) persons at low to moderate risk of cancer; (2) Utilize our existing
networks of community-based hospitals and primary care clinics to increase
CGN enrollment of African Americans and Latin Americans in the Washington,
D.C. area; (3) Contribute our well-validated IRB-approved protocols for
informed consent, pre-test education, and genetic counseling to the CGN; (4)
Provide CGN investigators with access to our state-of-the-art laboratory
technologies for diagnostic genetic analysis; (5) Utilize our existing
infrastructure for cancer DNA/tissue collection, processing, and storage to
contribute to basic cancer genetics research in the CGN; (6) Modify existing
cancer genetics educational materials to target African Americans and
develop Spanish language materials, consent forms and counseling protocols
for use with Latin Americans; (7) Provide genetics education and training
programs for a wide range of healthcare providers, including nurses and
medical students; and (8) Contribute our expertise conducting research on
the clinical, psychosocial, and economic outcomes of genetic testing for
cancer susceptibility.
Publications
None. See parent grant details.