Grant Details
Grant Number: |
1R03CA115191-01A2 Interpret this number |
Primary Investigator: |
Zhang, Amy |
Organization: |
Case Western Reserve University |
Project Title: |
Assessing Depression in African American Cancer Patients |
Fiscal Year: |
2006 |
Abstract
DESCRIPTION (provided by applicant): African Americans (AA) have the highest incidence and death rates from all cancers in the U.S. Adequate assessment and treatment of depression in AA cancer patients is essential to reduce this unequal burden of cancer and health disparity. Current knowledge of AA cancer patients' depression is extremely limited. A few existing studies suggest inadequate recognition of the extent of depression in this population. Currently no available instrument has been validated for screening depression of AA cancer patients, despite increasing evidence of cultural insensitivity of depression measures for African Americans. It is imperative to develop a culturally sensitive screening instrument for AA cancer patients' depression, in order to provide adequate referral and needed care. The development of this instrument would require a deep understanding of AA depressive experience. This application is the first study of the lived experience of depression in AA cancer patients. It is significant because of the large size of AA cancer population, the need to combat cancer disparity, and its implication for quality of life and long-term survival of AA cancer patients. Using a mixed design, the study will provide baseline knowledge of AA depressive experience and identify AA depressive symptoms as an initial step of the instrument construction. The specific aims are as follows: 1) Describe the meaning and structure of AA depressive experience in the context of living with cancer; 2) Compare depressed and nondepressed AA cancer patients to identify beliefs and attitudes about having cancer, which are associated with depression; and 3) Identify manifestations of AA depression and create a symptom catalogue that can be developed into a culturally sensitive screening instrument for assessing AA cancer patient's depression in a future study. The interview sample will consist of 80 cancer patients-20 patients in each of four groups: 3 AA groups and a white group consisting of two subgroups, varying by degree of depression. The group members will be further stratified by age and cancer diagnosis for an unstructured individual interview that will be audiotaped, transcribed, and analyzed verbatim. In the validation phase, an additional 10 AA cancer patients will be recruited to determine the credibility of study outcomes. Qualitative data analysis using the NUDIST software will identify themes and their relationships to describe: 1) meanings and structure of the lived depressive experience of AA cancer patients; 2) beliefs and attitudes about having cancer; and 3) self- explanations of depressive experiences. The mixed method analysis using statistical and qualitative methods will be used to identify AA depressive symptoms. Consequently, a symptom catalogue that inventories the identified AA depressive symptoms will be constructed so that a culturally sensitive screening instrument for assessing depression in AA cancer patients can be developed in a future study.
Publications
Social Support and Self-Coping of Depressed African-American Cancer Patients.
Authors: Gary F.
, Li R.
, Zhu H.
, Zhang A.Y.
, Killion C.
.
Source: Journal Of National Black Nurses' Association : Jnbna, 2016 Dec; 27(2), p. 11-19.
PMID: 29932591
Related Citations
Exploration Of Depressive Symptoms In African American Cancer Patients
Authors: Zhang A.Y.
, Gary F.
, Zhu H.
.
Source: Journal Of Mental Health (abingdon, England), 2015 Dec; 24(6), p. 351-6.
PMID: 25564890
Related Citations
Attitudes Toward Cancer And Implications For Mental Health Outcome In African-american Cancer Patients
Authors: Zhang A.Y.
, Gary F.
, Zhu H.
.
Source: Journal Of Cancer Education : The Official Journal Of The American Association For Cancer Education, 2015 Mar; 30(1), p. 138-44.
PMID: 25015841
Related Citations
Initial Evidence Of Religious Practice And Belief In Depressed African American Cancer Patients
Authors: Zhang A.Y.
, Gary F.
, Zhu H.
.
Source: The Open Nursing Journal, 2013; 7, p. 1-5.
PMID: 23346265
Related Citations
Discord Of Measurements In Assessing Depression Among African Americans With Cancer Diagnoses
Authors: Zhang A.Y.
, Gary F.
.
Source: International Journal Of Culture And Mental Health, 2013-01-01 00:00:00.0; 6(1), p. 58-71.
PMID: 23682296
Related Citations
What Precipitates Depression In African-american Cancer Patients? Triggers And Stressors
Authors: Zhang A.Y.
, Gary F.
, Zhu H.
.
Source: Palliative & Supportive Care, 2012 Dec; 10(4), p. 279-86.
PMID: 22436086
Related Citations
Discord Of Biological And Psychological Measures In A Group Of Depressed African American And White Cancer Patients
Authors: Zhang,A.Y.
.
Source: The Open Nursing Journal, 2011; 5, p. 60-4.
PMID: 22135714
Related Citations
Measurement of Irritability in Cancer Patients.
Authors: Zhang A.Y.
, Ganocy S.J.
.
Source: Nursing Research, 2020 Mar/Apr; 69(2), p. 91-99.
PMID: 31764606
Related Citations