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Grant Details

Grant Number: 5R03CA113086-02 Interpret this number
Primary Investigator: Mosavel, Maghboeba
Organization: Case Western Reserve University
Project Title: Cervical Cancer and the Mother-Daughter Relationship
Fiscal Year: 2006


DESCRIPTION (provided by applicant): Cervical cancer is a largely preventable disease when women receive regular pap smears. Estimates suggest that the introduction of pap smears to populations naive to screening reduces cervical cancer rates by 60-90% within three years of implementation. However, many women do not obtain screening because they know little about cervical cancer, fear the prospect of having a pap smear, or remain fatalistic about their health. Cervical cancer remains a major global problem. In South Africa, where we propose to conduct this study, cervical cancer is currently the second most common female cancer. The risk of developing cervical cancer for black South African women is 1 in 29. This extraordinarily high risk has been attributed, among other factors, to a lack of educational efforts aimed at informing women about cervical cancer and motivating them to utilize existing screening resources. In an effort to explore innovative and culturally appropriate strategies to promote screening, we have developed two specific aims: 1) explore the cervical cancer-related knowledge and behaviors of mothers and 2) explore the mother-daughter relationship and its potential for daughter-initiated cervical cancer prevention. This study plans to meet the first object through conducting focus groups with mothers. The second objective will be met by conducting semi-structured interviews to explore in-depth the dimensions of the mother-daughter relationship and the norms associated with advice giving and receiving, particularly health advice. Each of these aims will contribute formative data to better understand the potential of using daughters as advocates to promote cervical cancer screening with their mothers. Effective and innovative methods are needed to help promote screening for cervical cancer. The mother-daughter relationship offers unexplored opportunities for health promotion research and in particular for emphasizing the importance of pap smears. Finally, the mother-daughter relationship has implications for effecting inter-generational prevention behavior for cervical cancer.


South African, urban youth narratives: Resilience within community.
Authors: Mosavel M. , Ahmed R. , Ports K.A. , Simon C. .
Source: International journal of adolescence and youth, 2015-06-01; 20(2), p. 245-255.
PMID: 25897181
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Health promotion and cervical cancer in South Africa: why adolescent daughters can teach their mothers about early detection.
Authors: Mosavel M. .
Source: Health promotion international, 2012 Jun; 27(2), p. 157-66.
EPub date: 2011-03-18.
PMID: 21421580
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Getting personal: ethics and identity in global health research.
Authors: Simon C. , Mosavel M. .
Source: Developing world bioethics, 2011 Aug; 11(2), p. 82-92.
EPub date: 2011-03-22.
PMID: 21426482
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Community researchers conducting health disparities research: Ethical and other insights from fieldwork journaling.
Authors: Mosavel M. , Ahmed R. , Daniels D. , Simon C. .
Source: Social science & medicine (1982), 2011 Jul; 73(1), p. 145-52.
EPub date: 2011-05-30.
PMID: 21680071
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Cancer perceptions of South African mothers and daughters: implications for health promotion programs.
Authors: Mosavel M. , Simon C. , Ahmed R. .
Source: Health care for women international, 2010 Sep; 31(9), p. 784-800.
PMID: 20677037
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Community members as recruiters of human subjects: ethical considerations.
Authors: Simon C. , Mosavel M. .
Source: The American journal of bioethics : AJOB, 2010 Mar; 10(3), p. 3-11.
PMID: 20229402
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Response to open peer commentaries on "Community members as recruiters of human subjects: ethical considerations".
Authors: Simon C. , Mosavel M. .
Source: The American journal of bioethics : AJOB, 2010 Mar; 10(3), p. W1-3.
PMID: 20229401
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Exploratory Health Disparities Research: The Need to Provide a Tangible Benefit to Vulnerable Respondents.
Authors: Mosavel M. , Simon C. .
Source: Ethics & behavior, 2010; 20(1), p. 1-9.
PMID: 22211053
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Daughter-initiated health advice to mothers: perceptions of African-American and Latina daughters.
Authors: Mosavel M. , Thomas T. .
Source: Health education research, 2009 Oct; 24(5), p. 799-810.
EPub date: 2009-04-01.
PMID: 19339373
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Cervical cancer attitudes and beliefs-a Cape Town community responds on World Cancer Day.
Authors: Mosavel M. , Simon C. , Oakar C. , Meyer S. .
Source: Journal of cancer education : the official journal of the American Association for Cancer Education, 2009; 24(2), p. 114-9.
PMID: 19431027
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Key conceptual issues in the forging of "culturally competent" community health initiatives: a South African example.
Authors: Simon C. , Mosavel M. .
Source: Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees, 2008 Spring; 17(2), p. 195-205.
PMID: 18312734
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Ethical challenges in the design and conduct of locally relevant international health research.
Authors: Simon C. , Mosavel M. , van Stade D. .
Source: Social science & medicine (1982), 2007 May; 64(9), p. 1960-9.
EPub date: 2007-02-26.
PMID: 17321657
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The mother-daughter relationship: what is its potential as a locus for health promotion?
Authors: Mosavel M. , Simon C. , Van Stade D. .
Source: Health care for women international, 2006 Aug; 27(7), p. 646-64.
PMID: 16844676
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Community-based participatory research (CBPR) in South Africa: engaging multiple constituents to shape the research question.
Authors: Mosavel M. , Simon C. , van Stade D. , Buchbinder M. .
Source: Social science & medicine (1982), 2005 Dec; 61(12), p. 2577-87.
EPub date: 2005-06-13.
PMID: 15955605
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