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Grant Details

Grant Number: 5R24CA095835-05 Interpret this number
Primary Investigator: Mayo, Matthew
Organization: University Of Kansas Medical Center
Project Title: Biostatistics/Informatics Shared Resource
Fiscal Year: 2006
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Abstract

DESCRIPTION (provided by applicant): The global objective of the Biostatistics/Informatics Shared Resource( BSR) is to provide the infrastructure and expertise for centralized and project specific database development, management, and analysis. In addition, the BSR will ensure that all oncology and oncology-related researchers have ready access to consultation related to biostatistics/informatics. The BSR will provide data entry, management and analytic support and aid in the design of experiments for oncology and oncology-related studies conducted by researchers affiliated with the Kansas Cancer Institute and the University of Kansas Medical Center. The specific aims are to: 1) Provide statistical expertise in study design and protocol development for investigators, 2) Serve as a repository for all basic science, clinical and behavioral studies conducted by the investigators, 3) Coordinate the preparation of data collection forms, 4) Develop a standardized reporting format across all studies conducted by the investigators, 5) Develop a computerized data quality control, monitoring and management system, 6) Maintain study databases, 7) Train investigators and their staff in data collection and quality procedures and statistical methodology, 8) Perform appropriate statistical analyses of study data, 9) Participate in the preparation of study presentations and publications, 10) Develop statistical methodology to enhance study design and analysis and interpretation of results of studies conducted by the investigators, 1l) Further develop expertise in bioinformatics, 12) Generate randomization schemes for investigators' studies. The BSR faculty and staff have considerable experience and expertise and excellent facilities, which include up-to-date hardware and software provided by the Kansas Cancer Institute and the Department of Preventive Medicine. A Resource Advisory Group has been formed with expertise in oncology, biostatistics and informatics to advise the BSR on an ongoing basis.

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Publications

Evaluating the Completeness of the SEER-Medicare Linked Database for Oral and Pharyngeal Cancer.
Authors: Mahnken J.D. , Keighley J.D. , Cumming C.G. , Girod D.A. , Mayo M.S. .
Source: Journal of registry management, 2008-01-01; 35(4), p. 145-148.
PMID: 20936096
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Developmental trajectories of overweight during childhood: role of early life factors.
Authors: Li C. , Goran M.I. , Kaur H. , Nollen N. , Ahluwalia J.S. .
Source: Obesity (Silver Spring, Md.), 2007 Mar; 15(3), p. 760-71.
PMID: 17372328
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Bayesian sample size calculations in phase II clinical trials using a mixture of informative priors.
Authors: Gajewski B.J. , Mayo M.S. .
Source: Statistics in medicine, 2006-08-15; 25(15), p. 2554-66.
PMID: 16345057
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Treatment of pediatric suppurative mastoiditis: is peripherally inserted central catheter (PICC) antibiotic therapy necessary?
Authors: Moore J.A. , Wei J.L. , Smith H.J. , Mayo M.S. .
Source: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2006 Jul; 135(1), p. 106-10.
PMID: 16815193
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Some statistical issues in microarray gene expression data.
Authors: Mayo M.S. , Gajewski B.J. , Morris J.S. .
Source: Radiation research, 2006 Jun; 165(6), p. 745-8.
PMID: 16802876
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Birth weight, puberty, and systolic blood pressure in children and adolescents: a longitudinal analysis.
Authors: Li C. , Huang T.K. , Cruz M.L. , Goran M.I. .
Source: Journal of human hypertension, 2006 Jun; 20(6), p. 444-50.
PMID: 16617311
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Risk factors for lung cancer in Iowa women: implications for prevention.
Authors: Neuberger J.S. , Mahnken J.D. , Mayo M.S. , Field R.W. .
Source: Cancer detection and prevention, 2006; 30(2), p. 158-67.
EPub date: 2006-04-03.
PMID: 16581199
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The influence of depressive symptoms on smoking cessation among African Americans in a randomized trial of bupropion.
Authors: Catley D. , Harris K.J. , Okuyemi K.S. , Mayo M.S. , Pankey E. , Ahluwalia J.S. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2005 Dec; 7(6), p. 859-70.
PMID: 16298721
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Additive interactions of maternal prepregnancy BMI and breast-feeding on childhood overweight.
Authors: Li C. , Kaur H. , Choi W.S. , Huang T.T. , Lee R.E. , Ahluwalia J.S. .
Source: Obesity research, 2005 Feb; 13(2), p. 362-71.
PMID: 15800295
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Self-efficacy and motivation to quit during participation in a smoking cessation program.
Authors: Boardman T. , Catley D. , Mayo M.S. , Ahluwalia J.S. .
Source: International journal of behavioral medicine, 2005; 12(4), p. 266-72.
PMID: 16262545
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Comparison of smoking relapse curves among African-American smokers.
Authors: Choi W.S. , Okuyemi K.S. , Kaur H. , Ahluwalia J.S. .
Source: Addictive behaviors, 2004 Nov; 29(8), p. 1679-83.
PMID: 15451137
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Predictors of smoking cessation among African-Americans enrolled in a randomized controlled trial of bupropion.
Authors: Harris K.J. , Okuyemi K.S. , Catley D. , Mayo M.S. , Ge B. , Ahluwalia J.S. .
Source: Preventive medicine, 2004 Apr; 38(4), p. 498-502.
PMID: 15020185
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Bayesian sample size calculations in phase II clinical trials using informative conjugate priors.
Authors: Mayo M.S. , Gajewski B.J. .
Source: Controlled clinical trials, 2004 Apr; 25(2), p. 157-67.
PMID: 15020034
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Does menthol attenuate the effect of bupropion among African American smokers?
Authors: Okuyemi K.S. , Ahluwalia J.S. , Ebersole-Robinson M. , Catley D. , Mayo M.S. , Resnicow K. .
Source: Addiction (Abingdon, England), 2003 Oct; 98(10), p. 1387-93.
PMID: 14519175
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Overexpression of manganese superoxide dismutase selectively modulates the activity of Jun-associated transcription factors in fibrosarcoma cells.
Authors: Kiningham K.K. , St Clair D.K. .
Source: Cancer research, 1997-12-01; 57(23), p. 5265-71.
PMID: 9393747
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