Grant Number:	5R01CA106928-02 Interpret this number
Primary Investigator:	Kazak, Anne
Organization:	Children'S Hosp Of Philadelphia
Project Title:	Psychological Outcome in Childhood Cancer Survivors
Fiscal Year:	2005

DESCRIPTION (provided by applicant): Appropriate care for long-term survivors of childhood cancer depends on understanding the psychology being a young adult long-term survivor, including psychosocial late effects, reactions to follow-up care, and predictors of distress and participation in health care. Although young adult cancer survivors have elevated rates of distress relative to norms, it is not known how their distress compares to that reported by a matched of never ill peers, or how other variables related to health care might be associated with distress. Beliefs about one's medical vulnerability and medical competence (health competence beliefs; HCB) are theoretically related to distress and to participation in health care, although these relationships have not been examined empirically with long-term survivors of childhood cancer. This study aims to examine these links. Aim 1 identifies distress that is cancer-specific by comparing long-term survivors of childhood cancer to a matched group of well individuals at the time of a medical visit and two months later. Aim 2 proposes to develop a reliable and valid brief screening tool of health competence beliefs (HCB) that are associated with distress. Aim 3 proposes to test the association among survivors HCB, health risk knowledge, psychological distress, and follow-up care. Analysis of existing data and focus groups of 8-12 long-term survivors will be used to develop the HCB measure. After pilot feasbility testing, 150 16-39 year old long-term survivors of childhood cancer and 300 never ill young adults will complete questionnaires assessing beliefs and distress at a routine follow-up/health maintenance medical visit, and two months later (by mail or Internet). Survivors will also complete the questionnaires 12 months later; medical late effect and treatment intensity will be rated and contact with the oncology medical team will be tracked over 12 months. The findings of this study are expected to inform the structure of follow-up visits by providing a tool to identify distressed survivors, as well as guidelines to optimize patients adaptive beliefs about their health competence, thereby maximizing long-term survivors' use of health care and enhancing their physical and psychological well-being.




Relationship between sleep problems and psychological outcomes in adolescent and young adult cancer survivors and controls.
Authors: Daniel L. , Kazak A.E. , Li Y. , Hobbie W. , Ginsberg J. , Butler E. , Schwartz L. .
Source: Supportive Care In Cancer : Official Journal Of The Multinational Association Of Supportive Care In Cancer, 2016 Feb; 24(2), p. 539-46.
PMID: 26130364
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Why mothers accompany adolescent and young adult childhood cancer survivors to follow-up clinic visits.
Authors: Doshi K. , Kazak A.E. , Hocking M.C. , DeRosa B.W. , Schwartz L.A. , Hobbie W.L. , Ginsberg J.P. , Deatrick J. .
Source: Journal Of Pediatric Oncology Nursing : Official Journal Of The Association Of Pediatric Oncology Nurses, 2014 Jan-Feb; 31(1), p. 51-7.
PMID: 24451909
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Prospectively examining physical activity in young adult survivors of childhood cancer and healthy controls.
Authors: Hocking M.C. , Schwartz L.A. , Hobbie W.L. , Derosa B.W. , Ittenbach R.F. , Mao J.J. , Ginsberg J.P. , Kazak A.E. .
Source: Pediatric Blood & Cancer, 2013 Feb; 60(2), p. 309-15.
PMID: 22434746
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Screening for psychosocial risk in pediatric cancer.
Authors: Kazak A.E. , Brier M. , Alderfer M.A. , Reilly A. , Fooks Parker S. , Rogerwick S. , Ditaranto S. , Barakat L.P. .
Source: Pediatric Blood & Cancer, 2012 Nov; 59(5), p. 822-7.
PMID: 22492662
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A revision of the intensity of treatment rating scale: classifying the intensity of pediatric cancer treatment.
Authors: Kazak A.E. , Hocking M.C. , Ittenbach R.F. , Meadows A.T. , Hobbie W. , DeRosa B.W. , Leahey A. , Kersun L. , Reilly A. .
Source: Pediatric Blood & Cancer, 2012-07-15 00:00:00.0; 59(1), p. 96-9.
EPub date: 2012-07-15 00:00:00.0.
PMID: 21858914
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The role of beliefs in the relationship between health problems and posttraumatic stress in adolescent and young adult cancer survivors.
Authors: Schwartz L.A. , Kazak A.E. , Derosa B.W. , Hocking M.C. , Hobbie W.L. , Ginsberg J.P. .
Source: Journal Of Clinical Psychology In Medical Settings, 2012 Jun; 19(2), p. 138-46.
PMID: 21964825
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Profiles of Health Competence Beliefs Among Young Adult Survivors of Childhood Cancer.
Authors: Brier M.J. , Kazak A.E. , Derosa B.W. , Hocking M.C. , Schwartz L.A. , Ginsberg J.P. , Hobbie W. , Ittenbach R.F. .
Source: Journal Of Adolescent And Young Adult Oncology, 2011 Dec; 1(4), p. 195-202.
PMID: 23610738
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Measuring health-related beliefs of mothers of adolescent and young adult childhood cancer survivors.
Authors: Doshi K. , Kazak A.E. , Derosa B.W. , Schwartz L.A. , Hobbie W. , Ginsberg J. , Ittenbach R.F. .
Source: Families, Systems & Health : The Journal Of Collaborative Family Healthcare, 2011 Mar; 29(1), p. 55-63.
PMID: 21417524
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Development and validation of the health competence beliefs inventory in young adults with and without a history of childhood cancer.
Authors: DeRosa B.W. , Kazak A.E. , Doshi K. , Schwartz L.A. , Ginsberg J. , Mao J.J. , Straton J. , Hobbie W. , Rourke M.T. , Carlson C. , et al. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2011 Feb; 41(1), p. 48-58.
PMID: 20936390
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Self-reported health problems of young adults in clinical settings: survivors of childhood cancer and healthy controls.
Authors: Schwartz L.A. , Mao J.J. , Derosa B.W. , Ginsberg J.P. , Hobbie W.L. , Carlson C.A. , Mougianis I.D. , Ogle S.K. , Kazak A.E. .
Source: Journal Of The American Board Of Family Medicine : Jabfm, 2010 May-Jun; 23(3), p. 306-14.
PMID: 20453176
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Psychological outcomes and health beliefs in adolescent and young adult survivors of childhood cancer and controls.
Authors: Kazak A.E. , Derosa B.W. , Schwartz L.A. , Hobbie W. , Carlson C. , Ittenbach R.F. , Mao J.J. , Ginsberg J.P. .
Source: Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology, 2010-04-20 00:00:00.0; 28(12), p. 2002-7.
EPub date: 2010-04-20 00:00:00.0.
PMID: 20231679
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Classifying the intensity of pediatric cancer treatment protocols: the intensity of treatment rating scale 2.0 (ITR-2).
Authors: Werba B.E. , Hobbie W. , Kazak A.E. , Ittenbach R.F. , Reilly A.F. , Meadows A.T. .
Source: Pediatric Blood & Cancer, 2007-06-15 00:00:00.0; 48(7), p. 673-7.
PMID: 17427232
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