Skip to main content
An official website of the United States government
Grant Details

Grant Number: 5R01CA066635-09 Interpret this number
Primary Investigator: Sandler, Robert
Organization: Univ Of North Carolina Chapel Hill
Project Title: Population Study of Rectal Cancer in Blacks and Whites
Fiscal Year: 2005


Abstract

DESCRIPTION (provided by applicant): Between 1973 and 1995 the incidence of rectal cancer decreased 2.0 percent in blacks compared to 20.2 percent in whites. From 1989-94, the five-year relative survival was 52.5 percentin blacks and 63.0 percent in whites. These differences have not been explained. In fact, black-white differences in rectal cancer incidence and mortality have not been adequately studied. This competing renewal application seeks funds to conduct a population-based study of rectal cancer in blacks and whites in a 33-county area of North Carolina, building on the infrastructure developed in an ongoing and successful study of colon cancer. The primary goal of the proposed research is to examine possible exposure, susceptibility, and health care factors that might explain diverging incidence and mortality trends in blacks and whites. The specific aims of this research are: (1) To identify environmental and lifestyle risk factors for rectal cancer in blacks and whites. The proposed study will explore a range of exposures that may be related to rectal cancer. (2) To assess the prevalence and etiologic importance of specific inherited susceptibility characteristics in a large mixed-race population. The study will focus on the known alleles of the N-acetyltransferase genes (NAT1 and NAT2) and manganese superoxide dismutase (MnSOD) genes using DNA obtained from blood samples. The study will investigate interactions between these genes and environmental exposures. (3) To evaluate factors that might account for the higher mortality among blacks including poverty, insurance, access to care, delay in the medical system, and transportation. A secondary aim is to collect biological specimens for subsequent analyses such as the role of other inherited genetic characteristics and the presence or absence of specific somatic genetic alterations. The study will recruit 1000 cases of rectal cancer age 40-80 and 1000 population-based controls. Cancer cases (250 blacks and 750 whites) will be identified using the rapid ascertainment system of the North Carolina Central Cancer Registry. Controls (250 blacks and 750 whites) will be selected using Division of Motor Vehicle Registry data for those under age 65 and HCFA files for those age 65 and over. Dietary, lifestyle and environmental exposure information will be obtained for cases and controls by personal, in-home interviews. The interview instrument includes comprehensive questions concerning diet and the use of dietary supplements, and seeks information about medications, education, physical activity, poverty, health care access and utilization. DNA extracted from peripheral blood lymphocytes will be used to determine NAT and MnSOD genotypes.



Publications

Pathway Polygenic Risk Scores (pPRS) for the Analysis of Gene-environment Interaction.
Authors: Gauderman W.J. , Fu Y. , Queme B. , Kawaguchi E. , Wang Y. , Morrison J. , Brenner H. , Chan A. , Gruber S.B. , Keku T. , et al. .
Source: Biorxiv : The Preprint Server For Biology, 2024-12-19 00:00:00.0; , .
EPub date: 2024-12-19 00:00:00.0.
PMID: 39763728
Related Citations

Plasma Ghrelin and Risks of Sex-Specific, Site-Specific, and Early-Onset Colorectal Cancer: A Mendelian Randomization Analysis.
Authors: Hazelwood E. , Lopez Manzano C. , Vincent E.E. , Albanes D. , Bishop D.T. , Le Marchand L. , Ulrich C.M. , Peters U. , Murphy G. , Samadder N.J. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2024-12-02 00:00:00.0; 33(12), p. 1727-1732.
PMID: 39361354
Related Citations

Racial Differences in Over-the-Counter Non-steroidal Anti-inflammatory Drug Use Among Individuals at Risk of Adverse Cardiovascular Events.
Authors: Benson K.R.K. , Diamantidis C.J. , Davenport C.A. , Sandler R.S. , Boulware L.E. , Mohottige D. .
Source: Journal Of Racial And Ethnic Health Disparities, 2024 Oct; 11(5), p. 2816-2826.
EPub date: 2023-08-18 00:00:00.0.
PMID: 37594625
Related Citations

Sex hormones and risk of lung and colorectal cancers in women: a Mendelian randomization study.
Authors: Denos M. , Sun Y.Q. , Brumpton B. , Li Y. , Albanes D. , Burnett-Hartman A. , Campbell P.T. , Küry S. , Li C.I. , White E. , et al. .
Source: Research Square, 2024-04-10 00:00:00.0; , .
EPub date: 2024-04-10 00:00:00.0.
PMID: 38659935
Related Citations

Genome-Wide Gene-Environment Interaction Analyses to Understand the Relationship between Red Meat and Processed Meat Intake and Colorectal Cancer Risk.
Authors: Stern M.C. , Sanchez Mendez J. , Kim A.E. , Obón-Santacana M. , Moratalla-Navarro F. , Martín V. , Moreno V. , Lin Y. , Bien S.A. , Qu C. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2024-03-01 00:00:00.0; 33(3), p. 400-410.
PMID: 38112776
Related Citations

Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis.
Authors: Yarmolinsky J. , Robinson J.W. , Mariosa D. , Karhunen V. , Huang J. , Dimou N. , Murphy N. , Burrows K. , Bouras E. , Smith-Byrne K. , et al. .
Source: Ebiomedicine, 2024 Feb; 100, p. 104991.
EPub date: 2024-02-01 00:00:00.0.
PMID: 38301482
Related Citations

A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk.
Authors: Aglago E.K. , Kim A. , Lin Y. , Qu C. , Evangelou M. , Ren Y. , Morrison J. , Albanes D. , Arndt V. , Barry E.L. , et al. .
Source: Cancer Research, 2023-08-01 00:00:00.0; 83(15), p. 2572-2583.
PMID: 37249599
Related Citations

Identifying metabolic features of colorectal cancer liability using Mendelian randomization.
Authors: Bull C.J. , Hazelwood E. , Bell J.A. , Tan V.Y. , Constantinescu A.E. , Borges M.C. , Legge D.N. , Burrows K. , Huyghe J.R. , Brenner H. , et al. .
Source: Medrxiv : The Preprint Server For Health Sciences, 2023-07-17 00:00:00.0; , .
EPub date: 2023-07-17 00:00:00.0.
PMID: 36945480
Related Citations

Probing the diabetes and colorectal cancer relationship using gene - environment interaction analyses.
Authors: Dimou N. , Kim A.E. , Flanagan O. , Murphy N. , Diez-Obrero V. , Shcherbina A. , Aglago E.K. , Bouras E. , Campbell P.T. , Casey G. , et al. .
Source: British Journal Of Cancer, 2023-06-26 00:00:00.0; , .
EPub date: 2023-06-26 00:00:00.0.
PMID: 37365285
Related Citations

Association between circulating inflammatory markers and adult cancer risk: a Mendelian randomization analysis.
Authors: Yarmolinsky J. , Robinson J.W. , Mariosa D. , Karhunen V. , Huang J. , Dimou N. , Murphy N. , Burrows K. , Bouras E. , Smith-Byrne K. , et al. .
Source: Medrxiv : The Preprint Server For Health Sciences, 2023-05-05 00:00:00.0; , .
EPub date: 2023-05-05 00:00:00.0.
PMID: 37205426
Related Citations

Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation and immune response.
Authors: Carreras-Torres R. , Kim A.E. , Lin Y. , Díez-Obrero V. , Bien S.A. , Qu C. , Wang J. , Dimou N. , Aglago E.K. , Albanes D. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2022-12-28 00:00:00.0; , .
EPub date: 2022-12-28 00:00:00.0.
PMID: 36576985
Related Citations

Genetic Predictors for Fecal Propionate and Butyrate-Producing Microbiome Pathway are Not Associated with Colorectal Cancer Risk: A Mendelian Randomization Analysis.
Authors: Lu Y. , Zhao Y.C. , Chang-Claude J. , Gruber S.B. , Gsur A. , Offit K. , Vodickova L. , Woods M.O. , Nguyen L.H. , Wade K.H. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2022-12-13 00:00:00.0; , .
EPub date: 2022-12-13 00:00:00.0.
PMID: 36512731
Related Citations

Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.
Authors: Martin S. , Tyrrell J. , Thomas E.L. , Bown M.J. , Wood A.R. , Beaumont R.N. , Tsoi L.C. , Stuart P.E. , Elder J.T. , Law P. , et al. .
Source: Elife, 2022-01-25 00:00:00.0; 11, .
EPub date: 2022-01-25 00:00:00.0.
PMID: 35074047
Related Citations

Circulating Levels of Testosterone, Sex Hormone Binding Globulin and Colorectal Cancer Risk: Observational and Mendelian Randomization Analyses.
Authors: Dimou N. , Mori N. , Harlid S. , Harbs J. , Martin R.M. , Smith-Byrne K. , Papadimitriou N. , Bishop D.T. , Casey G. , Colorado-Yohar S.M. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2021 07; 30(7), p. 1336-1348.
EPub date: 2021-04-20 00:00:00.0.
PMID: 33879453
Related Citations

Nongenetic Determinants of Risk for Early-Onset Colorectal Cancer.
Authors: Archambault A.N. , Lin Y. , Jeon J. , Harrison T.A. , Bishop D.T. , Brenner H. , Casey G. , Chan A.T. , Chang-Claude J. , Figueiredo J.C. , et al. .
Source: Jnci Cancer Spectrum, 2021 Jun; 5(3), p. pkab029.
EPub date: 2021-05-20 00:00:00.0.
PMID: 34041438
Related Citations

Causal Effects of Lifetime Smoking on Breast and Colorectal Cancer Risk: Mendelian Randomization Study.
Authors: Dimou N. , Yarmolinsky J. , Bouras E. , Tsilidis K.K. , Martin R.M. , Lewis S.J. , Gram I.T. , Bakker M.F. , Brenner H. , Figueiredo J.C. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2021 May; 30(5), p. 953-964.
EPub date: 2021-03-02 00:00:00.0.
PMID: 33653810
Related Citations

A Combined Proteomics and Mendelian Randomization Approach to Investigate the Effects of Aspirin-Targeted Proteins on Colorectal Cancer.
Authors: Nounu A. , Greenhough A. , Heesom K.J. , Richmond R.C. , Zheng J. , Weinstein S.J. , Albanes D. , Baron J.A. , Hopper J.L. , Figueiredo J.C. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2020-12-14 00:00:00.0; , .
EPub date: 2020-12-14 00:00:00.0.
PMID: 33318029
Related Citations

Identifying novel susceptibility genes for colorectal cancer risk from a transcriptome-wide association study of 125,478 subjects.
Authors: Guo X. , Lin W. , Wen W. , Huyghe J. , Bien S. , Cai Q. , Harrison T. , Chen Z. , Qu C. , Bao J. , et al. .
Source: Gastroenterology, 2020-10-12 00:00:00.0; , .
EPub date: 2020-10-12 00:00:00.0.
PMID: 33058866
Related Citations

Circulating adipokine concentrations and risk of five obesity-related cancers: A Mendelian randomization study.
Authors: Dimou N.L. , Papadimitriou N. , Mariosa D. , Johansson M. , Brennan P. , Peters U. , Chanock S.J. , Purdue M. , Bishop D.T. , Gago-Dominquez M. , et al. .
Source: International Journal Of Cancer, 2020-10-10 00:00:00.0; , .
EPub date: 2020-10-10 00:00:00.0.
PMID: 33038280
Related Citations

Identification of Novel Loci and New Risk Variant in Known Loci for Colorectal Cancer Risk in East Asians.
Authors: Lu Y. , Kweon S.S. , Cai Q. , Tanikawa C. , Shu X.O. , Jia W.H. , Xiang Y.B. , Huyghe J.R. , Harrison T.A. , Kim J. , et al. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2020 02; 29(2), p. 477-486.
EPub date: 2019-12-11 00:00:00.0.
PMID: 31826910
Related Citations

Cumulative Burden of Colorectal Cancer-Associated Genetic Variants is More Strongly Associated With Early-onset vs Late-onset Cancer.
Authors: Archambault A.N. , Su Y.R. , Jeon J. , Thomas M. , Lin Y. , Conti D.V. , Win A.K. , Sakoda L.C. , Lansdorp-Vogelaar I. , Peterse E.F. , et al. .
Source: Gastroenterology, 2019-12-19 00:00:00.0; , .
EPub date: 2019-12-19 00:00:00.0.
PMID: 31866242
Related Citations

Lifestyle Factors, Colorectal Tumor Methylation, and Survival Among African Americans and European Americans.
Authors: Busch E.L. , Galanko J.A. , Sandler R.S. , Goel A. , Keku T.O. .
Source: Scientific Reports, 2018-06-21 00:00:00.0; 8(1), p. 9470.
EPub date: 2018-06-21 00:00:00.0.
PMID: 29930328
Related Citations

Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.
Authors: Wang H. , Schmit S.L. , Haiman C.A. , Keku T.O. , Kato I. , Palmer J.R. , van den Berg D. , Wilkens L.R. , Burnett T. , Conti D.V. , et al. .
Source: International Journal Of Cancer, 2017-06-15 00:00:00.0; 140(12), p. 2728-2733.
EPub date: 2017-06-15 00:00:00.0.
PMID: 28295283
Related Citations

Interaction between Red Meat Intake and NAT2 Genotype in Increasing the Risk of Colorectal Cancer in Japanese and African Americans.
Authors: Wang H. , Iwasaki M. , Haiman C.A. , Kono S. , Wilkens L.R. , Keku T.O. , Berndt S.I. , Tsugane S. , Le Marchand L. .
Source: Plos One, 2015; 10(12), p. e0144955.
PMID: 26683305
Related Citations

Shared and independent colorectal cancer risk alleles in TGFß-related genes in African and European Americans.
Authors: Kupfer S.S. , Skol A.D. , Hong E. , Ludvik A. , Kittles R.A. , Keku T.O. , Sandler R.S. , Ellis N.A. .
Source: Carcinogenesis, 2014 Sep; 35(9), p. 2025-30.
PMID: 24753543
Related Citations

Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A.
Authors: Wang H. , Burnett T. , Kono S. , Haiman C.A. , Iwasaki M. , Wilkens L.R. , Loo L.W. , Van Den Berg D. , Kolonel L.N. , Henderson B.E. , et al. .
Source: Nature Communications, 2014-08-08 00:00:00.0; 5, p. 4613.
EPub date: 2014-08-08 00:00:00.0.
PMID: 25105248
Related Citations

Nucleotide excision repair gene polymorphisms, meat intake and colon cancer risk.
Authors: Steck S.E. , Butler L.M. , Keku T. , Antwi S. , Galanko J. , Sandler R.S. , Hu J.J. .
Source: Mutation Research, 2014 Apr; 762, p. 24-31.
PMID: 24607854
Related Citations

Fine-mapping of genome-wide association study-identified risk loci for colorectal cancer in African Americans.
Authors: Wang H. , Haiman C.A. , Burnett T. , Fortini B.K. , Kolonel L.N. , Henderson B.E. , Signorello L.B. , Blot W.J. , Keku T.O. , Berndt S.I. , et al. .
Source: Human Molecular Genetics, 2013-12-15 00:00:00.0; 22(24), p. 5048-55.
EPub date: 2013-12-15 00:00:00.0.
PMID: 23851122
Related Citations

Somatic gene mutations in African Americans may predict worse outcomes in colorectal cancer.
Authors: Kang M. , Shen X.J. , Kim S. , Araujo-Perez F. , Galanko J.A. , Martin C.F. , Sandler R.S. , Keku T.O. .
Source: Cancer Biomarkers : Section A Of Disease Markers, 2013; 13(5), p. 359-66.
PMID: 24440976
Related Citations

Genetic variants in IGF-I, IGF-II, IGFBP-3, and adiponectin genes and colon cancer risk in African Americans and Whites.
Authors: Keku T.O. , Vidal A. , Oliver S. , Hoyo C. , Hall I.J. , Omofoye O. , McDoom M. , Worley K. , Galanko J. , Sandler R.S. , et al. .
Source: Cancer Causes & Control : Ccc, 2012 Jul; 23(7), p. 1127-38.
PMID: 22565227
Related Citations

A high-fiber diet does not protect against asymptomatic diverticulosis.
Authors: Peery A.F. , Barrett P.R. , Park D. , Rogers A.J. , Galanko J.A. , Martin C.F. , Sandler R.S. .
Source: Gastroenterology, 2012 Feb; 142(2), p. 266-72.e1.
PMID: 22062360
Related Citations

IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites.
Authors: Hoyo C. , Murphy S.K. , Schildkraut J.M. , Vidal A.C. , Skaar D. , Millikan R.C. , Galanko J. , Sandler R.S. , Jirtle R. , Keku T. .
Source: Disease Markers, 2012; 32(2), p. 133-41.
PMID: 22377707
Related Citations

Characterization of the colorectal cancer-associated enhancer MYC-335 at 8q24: the role of rs67491583.
Authors: Tuupanen S. , Yan J. , Turunen M. , Gylfe A.E. , Kaasinen E. , Li L. , Eng C. , Culver D.A. , Kalady M.F. , Pennison M.J. , et al. .
Source: Cancer Genetics, 2012 Jan-Feb; 205(1-2), p. 25-33.
PMID: 22429595
Related Citations

Inverse relationship between moderate alcohol intake and rectal cancer: analysis of the North Carolina Colon Cancer Study.
Authors: Crockett S.D. , Long M.D. , Dellon E.S. , Martin C.F. , Galanko J.A. , Sandler R.S. .
Source: Diseases Of The Colon And Rectum, 2011 Jul; 54(7), p. 887-94.
PMID: 21654257
Related Citations

Genetic associations in the vitamin D receptor and colorectal cancer in African Americans and Caucasians.
Authors: Kupfer S.S. , Anderson J.R. , Ludvik A.E. , Hooker S. , Skol A. , Kittles R.A. , Keku T.O. , Sandler R.S. , Ruiz-Ponte C. , Castellvi-Bel S. , et al. .
Source: Plos One, 2011; 6(10), p. e26123.
PMID: 22046258
Related Citations

Genetic heterogeneity in colorectal cancer associations between African and European americans.
Authors: Kupfer S.S. , Anderson J.R. , Hooker S. , Skol A. , Kittles R.A. , Keku T.O. , Sandler R.S. , Ellis N.A. .
Source: Gastroenterology, 2010 Nov; 139(5), p. 1677-85, 1685.e1-8.
PMID: 20659471
Related Citations

Antioxidant and DNA methylation-related nutrients and risk of distal colorectal cancer.
Authors: Williams C.D. , Satia J.A. , Adair L.S. , Stevens J. , Galanko J. , Keku T.O. , Sandler R.S. .
Source: Cancer Causes & Control : Ccc, 2010 Aug; 21(8), p. 1171-81.
PMID: 20352485
Related Citations

Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African Americans.
Authors: Kim S. , Sandler D.P. , Galanko J. , Martin C. , Sandler R.S. .
Source: American Journal Of Epidemiology, 2010-05-01 00:00:00.0; 171(9), p. 969-79.
EPub date: 2010-05-01 00:00:00.0.
PMID: 20392864
Related Citations

trans-Fatty acid consumption and its association with distal colorectal cancer in the North Carolina Colon Cancer Study II.
Authors: Vinikoor L.C. , Millikan R.C. , Satia J.A. , Schroeder J.C. , Martin C.F. , Ibrahim J.G. , Sandler R.S. .
Source: Cancer Causes & Control : Ccc, 2010 Jan; 21(1), p. 171-80.
PMID: 19842051
Related Citations

Associations of red meat, fat, and protein intake with distal colorectal cancer risk.
Authors: Williams C.D. , Satia J.A. , Adair L.S. , Stevens J. , Galanko J. , Keku T.O. , Sandler R.S. .
Source: Nutrition And Cancer, 2010; 62(6), p. 701-9.
PMID: 20661817
Related Citations

A randomized trial of tailoring and motivational interviewing to promote fruit and vegetable consumption for cancer prevention and control.
Authors: Campbell M.K. , Carr C. , Devellis B. , Switzer B. , Biddle A. , Amamoo M.A. , Walsh J. , Zhou B. , Sandler R. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2009 Oct; 38(2), p. 71-85.
PMID: 20012809
Related Citations

Dietary patterns, food groups, and rectal cancer risk in Whites and African-Americans.
Authors: Williams C.D. , Satia J.A. , Adair L.S. , Stevens J. , Galanko J. , Keku T.O. , Sandler R.S. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2009 May; 18(5), p. 1552-61.
PMID: 19423533
Related Citations

The association between diabetes, insulin use, and colorectal cancer among Whites and African Americans.
Authors: Vinikoor L.C. , Long M.D. , Keku T.O. , Martin C.F. , Galanko J.A. , Sandler R.S. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2009 Apr; 18(4), p. 1239-42.
PMID: 19336553
Related Citations

Selenium, folate, and colon cancer.
Authors: Connelly-Frost A. , Poole C. , Satia J.A. , Kupper L.L. , Millikan R.C. , Sandler R.S. .
Source: Nutrition And Cancer, 2009; 61(2), p. 165-78.
PMID: 19235033
Related Citations

Dietary patterns and colon cancer risk in Whites and African Americans in the North Carolina Colon Cancer Study.
Authors: Satia J.A. , Tseng M. , Galanko J.A. , Martin C. , Sandler R.S. .
Source: Nutrition And Cancer, 2009; 61(2), p. 179-93.
PMID: 19235034
Related Citations

Associations between trans fatty acid consumption and colon cancer among Whites and African Americans in the North Carolina colon cancer study I.
Authors: Vinikoor L.C. , Satia J.A. , Schroeder J.C. , Millikan R.C. , Martin C.F. , Ibrahim J.G. , Sandler R.S. .
Source: Nutrition And Cancer, 2009; 61(4), p. 427-36.
PMID: 19838914
Related Citations

Use of nonsteroidal antiinflammatory drugs and distal large bowel cancer in whites and African Americans.
Authors: Kim S. , Martin C. , Galanko J. , Woosley J.T. , Schroeder J.C. , Keku T.O. , Satia J.A. , Halabi S. , Sandler R.S. .
Source: American Journal Of Epidemiology, 2008-12-01 00:00:00.0; 168(11), p. 1292-300.
EPub date: 2008-12-01 00:00:00.0.
PMID: 18945689
Related Citations

UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.
Authors: Girard H. , Butler L.M. , Villeneuve L. , Millikan R.C. , Sinha R. , Sandler R.S. , Guillemette C. .
Source: Mutation Research, 2008-09-26 00:00:00.0; 644(1-2), p. 56-63.
EPub date: 2008-09-26 00:00:00.0.
PMID: 18675828
Related Citations

Studying genetic research participants: lessons from the "Learning About Research in North Carolina" study.
Authors: Corbie-Smith G. , Blumenthal C. , Henderson G. , Garrett J. , Bussey-Jones J. , Moloney M. , Sandler R.S. , Lloyd S.W. , Dorrance J. , Darter J. .
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2008 Aug; 17(8), p. 2019-24.
PMID: 18708393
Related Citations

Modification by N-acetyltransferase 1 genotype on the association between dietary heterocyclic amines and colon cancer in a multiethnic study.
Authors: Butler L.M. , Millikan R.C. , Sinha R. , Keku T.O. , Winkel S. , Harlan B. , Eaton A. , Gammon M.D. , Sandler R.S. .
Source: Mutation Research, 2008-02-01 00:00:00.0; 638(1-2), p. 162-74.
EPub date: 2008-02-01 00:00:00.0.
PMID: 18022202
Related Citations



Back to Top