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Grant Details

Grant Number: 5R01CA079946-05 Interpret this number
Primary Investigator: Mckay, H
Organization: Oregon Research Institute
Project Title: Interactive Internet Interventions for Smoking
Fiscal Year: 2005


DESCRIPTION (provided by investigator): There is an important need for validated, low-cost smoking cessation interventions that can reach large populations of smokers. Internet-based cessation programs can reach an increasingly large number of smokers. Approximately one third of all persons are Internet users; an estimated 8 million of them are cigarette smokers. Internet-based smoking cessation programs can be interactive, personalize information based on participant characteristics and interests, provide a high degree of choice and flexibility, and provide social support from both peers and professionals. While initial start-up costs can be high, interactive Internet interventions cost little to maintain, and provide 24-hour/7-day access to smoking cessation assistance. We will develop a comprehensive Internet smoking cessation program with three major components: (a) support for the use of efficacious pharmacological therapies (e.g., nicotine replacement therapy and Zyban), (b) a cognitive-behavioral skills development, and (c) social support (primarily via on-line forums and chat rooms), and evaluate it in a randomized control trial designed to assess the impact of the program. The control condition will be an exercise and nutrition program of proven efficacy (PACE+) designed for Internet use. This program serves as a credible attention-placebo control. Approximately 2000 persons will be enrolled from large worksites that provide intranet links (and high-bandwidth connections) to our website. All assessment will be accomplished via the Internet and much of the process data--use of various intervention elements and transcripts of discussion groups--is recorded and stored automatically. Seven-day point prevalence cessation at three- and six-month follow-ups will serve as the primary outcomes, augmented by other prevalence and sustained quit outcomes. A variety of subject characteristics and process measures will be examined as predictors or mediators. After outcomes are assessed at six months, participants will be given access to the contrasting condition and encouraged to enroll. Secondary analyses will examine the effectiveness of the PACE+ program. The proposed design will provide important practical information about effectiveness of a low-cost Internet intervention to assist smokers in stopping smoking.


Use of non-assigned smoking cessation programs among participants of a Web-based randomized controlled trial.
Authors: Danaher B.G. , Lichtenstein E. , McKay H.G. , Seeley J.R. .
Source: Journal of medical Internet research, 2009-06-25; 11(2), p. e26.
EPub date: 2009-06-25.
PMID: 19632976
Related Citations

Comparing two web-based smoking cessation programs: randomized controlled trial.
Authors: McKay H.G. , Danaher B.G. , Seeley J.R. , Lichtenstein E. , Gau J.M. .
Source: Journal of medical Internet research, 2008-11-18; 10(5), p. e40.
EPub date: 2008-11-18.
PMID: 19017582
Related Citations

Measuring participant rurality in Web-based interventions.
Authors: Danaher B.G. , Hart L.G. , McKay H.G. , Severson H.H. .
Source: BMC public health, 2007-08-31; 7, p. 228.
EPub date: 2007-08-31.
PMID: 17764564
Related Citations

Bandwidth constraints to using video and other rich media in behavior change websites.
Authors: Danaher B.G. , Jazdzewski S.A. , McKay H.G. , Hudson C.R. .
Source: Journal of medical Internet research, 2005-09-16; 7(4), p. e49.
EPub date: 2005-09-16.
PMID: 16236701
Related Citations

The information architecture of behavior change websites.
Authors: Danaher B.G. , McKay H.G. , Seeley J.R. .
Source: Journal of medical Internet research, 2005-05-18; 7(2), p. e12.
EPub date: 2005-05-18.
PMID: 15914459
Related Citations

Evaluation of an Internet-based smoking cessation program: lessons learned from a pilot study.
Authors: Feil E.G. , Noell J. , Lichtenstein E. , Boles S.M. , McKay H.G. .
Source: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2003 Apr; 5(2), p. 189-94.
PMID: 12745491
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