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Grant Details

Grant Number: 7R01CA075003-03 Interpret this number
Primary Investigator: Albrecht, Terrance
Organization: Wayne State University
Project Title: Effects of Physician Communication on Patient Accrual
Fiscal Year: 2003


DESCRIPTION (investigator's abstract): The Institute of Medicine recommends that providing "access to high quality clinical trials" and "policies to ensure full disclosure of information about appropriate treatment options" could improve clinical care. This revised application addresses these areas by investigating patient (PT) and physician (MD) communication behaviors and their relationship to treatment decisions, generally, and participating in a clinical trial, specifically. Previous work by the principal investigator has demonstrated that PT-MD communication is linked to patient decisions about treatment choices (i.e. whether to participate in a clinical trial) and that significant variability and problems exist in the ways physicians explain clinical trials and treatment options to patients and their families. The objective of this study is to demonstrate the role of PT-MD communication on treatment decision-making while considering predisposing factors of the patient (including sociodemographic variables, coping style, preference for information, perceived life expectancy), predisposing factors of the physician (sociodemographic and attitudinal), the features of the protocol and the impact of the presence of a key family member (usually a spouse) on the interaction. The central hypothesis is that the PT-MD interaction mediates the predisposing factors of the PT, MD and protocol and is therefore the important element in understanding and explaining cancer PT's decisions about treatment options. In addition, it is hypothesized that the presence and participation of a family member significantly increases the complexity of the interaction and needs to be systematically assessed to better understand how PTs make treatment decisions and how communication with MDs can be improved. The encounter in which a clinical trial is discussed is the observational unit. At Time 1, self-reported data on predisposing variables will be collected from 260 adult cancer patients (eligible for a Phase II or Phase III clinical trial and who have a key family member with them), and 50-68 MDs at two sites, the Moffit Cancer Center (Tampa) and the Cancer Center at the Albany Medical Center (Albany NY). At Time 2, the PT-MD interaction in (the presentation and discussion of the option to enroll in a clinical trial) will be videotaped. These data will be coded using the Moffit Accrual Analysis System (MAAS). Interactions between the family member and the MD also will be videotaped, coded and analyzed. At Time 3, an interview will be conducted with the patients to assess their decision, perceptions of factors leading to the decision, comfort level with the decision and the process, their sense of therapeutic alliance with the MD, and the role of the key family member in the decision-making process.


A disparity of words: racial differences in oncologist-patient communication about clinical trials.
Authors: Eggly S. , Barton E. , Winckles A. , Penner L.A. , Albrecht T.L. .
Source: Health expectations : an international journal of public participation in health care and health policy, 2015 Oct; 18(5), p. 1316-26.
EPub date: 2013-08-02.
PMID: 23910630
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Strategies of persuasion in offers to participate in cancer clinical trials I: Topic placement and topic framing.
Authors: Barton E. , Eggly S. , Winckles A. , Albrecht T.L. .
Source: Communication & medicine, 2014; 11(1), p. 1-14.
PMID: 26402960
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The influence of patient expectations regarding cure on treatment decisions.
Authors: Gleason M.E. , Harper F.W. , Eggly S. , Ruckdeschel J.C. , Albrecht T.L. .
Source: Patient education and counseling, 2009 May; 75(2), p. 263-9.
EPub date: 2009-01-14.
PMID: 19147315
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Influence of clinical communication on patients' decision making on participation in clinical trials.
Authors: Albrecht T.L. , Eggly S.S. , Gleason M.E. , Harper F.W. , Foster T.S. , Peterson A.M. , Orom H. , Penner L.A. , Ruckdeschel J.C. .
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-06-01; 26(16), p. 2666-73.
PMID: 18509178
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Oncologists' recommendations of clinical trial participation to patients.
Authors: Eggly S. , Albrecht T.L. , Harper F.W. , Foster T. , Franks M.M. , Ruckdeschel J.C. .
Source: Patient education and counseling, 2008 Jan; 70(1), p. 143-8.
EPub date: 2007-11-05.
PMID: 17983722
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The roles of patients' internet use for cancer information and socioeconomic status in oncologist-patient communication.
Authors: Welch Cline R.J. , Penner L.A. , Harper F.W. , Foster T.S. , Ruckdeschel J.C. , Albrecht T.L. .
Source: Journal of oncology practice, 2007 May; 3(3), p. 167-71.
PMID: 20859403
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Information seeking during "bad news" oncology interactions: Question asking by patients and their companions.
Authors: Eggly S. , Penner L.A. , Greene M. , Harper F.W. , Ruckdeschel J.C. , Albrecht T.L. .
Source: Social science & medicine (1982), 2006 Dec; 63(11), p. 2974-85.
EPub date: 2006-09-07.
PMID: 16962218
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Discussing bad news in the outpatient oncology clinic: rethinking current communication guidelines.
Authors: Eggly S. , Penner L. , Albrecht T.L. , Cline R.J. , Foster T. , Naughton M. , Peterson A. , Ruckdeschel J.C. .
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-02-01; 24(4), p. 716-9.
PMID: 16446346
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Communication and informed consent.
Authors: Albrecht T.L. , Franks M.M. , Ruckdeschel J.C. .
Source: Current opinion in oncology, 2005 Jul; 17(4), p. 336-9.
PMID: 15933463
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A portable, unobtrusive device for videorecording clinical interactions.
Authors: Albrecht T.L. , Ruckdeschel J.C. , Ray F.L. , Pethe B.J. , Riddle D.L. , Strohm J. , Penner L.A. , Coovert M.D. , Quinn G. , Blanchard C.G. .
Source: Behavior research methods, 2005 Feb; 37(1), p. 165-9.
PMID: 16097357
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Understanding patient decisions about clinical trials and the associated communication process: a preliminary report.
Authors: Albrecht T.L. , Penner L.A. , Ruckdeschel J.C. .
Source: Journal of cancer education : the official journal of the American Association for Cancer Education, 2003 Winter; 18(4), p. 210-4.
PMID: 14766331
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