Grant Number:	5R01MH057738-05 Interpret this number
Primary Investigator:	Redd, William
Organization:	Mount Sinai School Of Medicine
Project Title:	Maternal Distress, Cognitive Processing & Pediatric Bmt
Fiscal Year:	2002

DESCRIPTION (Adapted from the Applicant's Abstract): The proposed research will investigate the role of cognitive/social processing in maternal distress associated with pediatric bone marrow transplantation (BMT) in the treatment of pediatric cancer. Although heightened levels of distress among these mothers has been documented in clinical studies, little is known about the course of such distress during and after BMT or factors that place mothers at increased risk for adjustment problems. The research is guided by the integration of current models of cognitive/social processing. According to these models, the psychosocial impact of severe negative life events is related to how well the individual is able to integrate the event into his/her beliefs. This recovery process can be stifled when social constraints on talking about the event exist. In the proposed longitudinal analysis 509 mothers will be recruited to participate in a series of five structured interviews during the course of their child's BMT. Assessments of psychosocial and background factors will be conducted two weeks before BMT hospitalization, during the acute BMT hospitalization, and at 6, 12, and 18 months post-BMT. Specific aims are to: 1) examine the course of psychological distress among mothers of children undergoing BMT; 2) determine the role of cognitive and social processing in the development and maintenance of mothers' psychological distress during and after their children's BMT; and 3) assess how dispositional optimism, monitoring coping style, and prior negative life events influence mothers' cognitive processing and development/maintenance of psychological distress. A combination of latent growth curve and structural equation modeling will be used in the data analysis.




Pre-bereavement meaning and post-bereavement distress in mothers of children who underwent haematopoietic stem cell transplantation.
Authors: Wu L. , Bonanno G. , Duhamel K. , Redd W.H. , Rini C. , Austin J. , Nereo N. , Ostroff J. , Parsons S. , Martini R. , et al. .
Source: British Journal Of Health Psychology, 2008 Sep; 13(Pt 3), p. 419-33.
PMID: 17535504
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Authors: Rini C. , Manne S. , DuHamel K. , Austin J. , Ostroff J. , Boulad F. , Parsons S.K. , Martini R. , Williams S.E. , Mee L. , et al. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2008 Sep; 27(5), p. 593-603.
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Optimism and life events as predictors of fear appraisals in mothers of children undergoing hematopoietic stem cell transplantation.
Authors: DuHamel K.N. , Rini C. , Austin J. , Ostroff J. , Parsons S. , Martini R. , Williams S. , Mee L. , Sexson S. , Winkel G. , et al. .
Source: Psycho-oncology, 2007 Sep; 16(9), p. 821-33.
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Maternal perspectives on children's health-related quality of life during the first year after pediatric hematopoietic stem cell transplant.
Authors: Parsons S.K. , Shih M.C. , Duhamel K.N. , Ostroff J. , Mayer D.K. , Austin J. , Martini D.R. , Williams S.E. , Mee L. , Sexson S. , et al. .
Source: Journal Of Pediatric Psychology, 2006 Nov-Dec; 31(10), p. 1100-15.
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Mothers' perceptions of benefit following pediatric stem cell transplantation: a longitudinal investigation of the roles of optimism, medical risk, and sociodemographic resources.
Authors: Rini C. , Manne S. , DuHamel K.N. , Austin J. , Ostroff J. , Boulad F. , Parsons S.K. , Martini R. , Williams S.E. , Mee L. , et al. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2004 Oct; 28(2), p. 132-41.
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Changes in mothers' basic beliefs following a child's bone marrow transplantation: the role of prior trauma and negative life events.
Authors: Rini C. , Manne S. , DuHamel K.N. , Austin J. , Ostroff J. , Boulad F. , Parsons S.K. , Martini R. , Williams S. , Mee L. , et al. .
Source: Journal Of Traumatic Stress, 2004 Aug; 17(4), p. 325-33.
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Source: Pediatrics, 2004 Jun; 113(6), p. 1700-8.
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Commentary: The evolution of evidence-based psychotherapy.
Authors: Redd W.H. .
Source: Journal Of Clinical Psychology, 2004 Apr; 60(4), p. 443-6.
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Cognitive processing among mothers of children undergoing bone marrow/stem cell transplantation.
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Source: Psychosomatic Medicine, 2004 Jan-Feb; 66(1), p. 92-103.
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Perceived partner critical and avoidant behaviors as predictors of anxious and depressive symptoms among mothers of children undergoing hemopaietic stem cell transplantation.
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Coping and the course of mother's depressive symptoms during and after pediatric bone marrow transplantation.
Authors: Manne S. , Duhamel K. , Ostroff J. , Parsons S. , Martini D.R. , Williams S.E. , Mee L. , Sexson S. , Austin J. , Winkel G. , et al. .
Source: Journal Of The American Academy Of Child And Adolescent Psychiatry, 2003 Sep; 42(9), p. 1055-68.
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Predictors of PTSD in mothers of children undergoing bone marrow transplantation: the role of cognitive and social processes.
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Source: Journal Of Pediatric Psychology, 2002 Oct-Nov; 27(7), p. 607-17.
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Anxiety and depression in mothers of children undergoing bone marrow transplant: symptom prevalence and use of the Beck depression and Beck anxiety inventories as screening instruments.
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