Grant Details
Grant Number: |
5R03CA088598-02 Interpret this number |
Primary Investigator: |
Moadel, Alyson |
Organization: |
Albert Einstein Col Of Med Yeshiva Univ |
Project Title: |
Effects of Yoga on Quality of Life During Breast Cancer |
Fiscal Year: |
2002 |
Abstract
DESCRIPTION: (provided by applicant)
Breast cancer and its treatment are often associated with great psychological,
physical and functional impairment. Recent research indicates that newly
diagnosed cancer patients of all cultural backgrounds are seeking out
increased behavioral/complementary medicine modalities to help them cope with
cancer and its treatment. Yoga is one such practice that is becoming
increasingly popular among cancer support organizations and cancer patients.
While Yoga has been empirically shown to provide numerous physical and
psychological benefits in both healthy and chronically ill individuals, there
has been only one published study to date of Yoga's effects on quality of life
(QOL) in cancer patients. The overall aim of this pilot study is to examine
the effect of a Yoga intervention to improve QOL among breast cancer patients
receiving chemotherapy within an urban, multi-ethnic cancer center. This
clinical trial will utilize a stratified (by type of chemotherapy)-randomized,
prospective, single-blinded design. Breast cancer patients (n=130) will be
randomly assigned (before the initiation of chemotherapy) to either a Yoga
program (n=65), or a Wait List Control group (n=65; Standard Care), and
followed for a 3-month period. Measures will be obtained at three time
points: baseline (T1) (prior to chemotherapy and group assignment), at one
month (T2); and at three months (T3), by blinded interviewers using
standardized QOL measurements (e.g., Functional Assessment of Cancer Therapy)
and clinician ratings. Objective health measures will include adverse medical
events and treatment compliance. Multivariate analyses will be used to
examine the hypothesis that a Yoga program will improve upon overall QOL by at
least 15 percent (based on a .25 effect size) in comparison to Standard Care.
Publications
Randomized Controlled Trial Of Yoga Among A Multiethnic Sample Of Breast Cancer Patients: Effects On Quality Of Life
Authors: Moadel A.B.
, Shah C.
, Wylie-Rosett J.
, Harris M.S.
, Patel S.R.
, Hall C.B.
, Sparano J.A.
.
Source: Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology, 2007-10-01 00:00:00.0; 25(28), p. 4387-95.
PMID: 17785709
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