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Grant Details

Grant Number: 5R01CA084225-02 Interpret this number
Primary Investigator: Severson, Herbert
Organization: Oregon Research Institute
Project Title: Xchew Net-Internet Smokeless Tobacco Cessation
Fiscal Year: 2002


Abstract

DESCRIPTION: While cigarette smoking has steadily declined for several years, the use of smokeless tobacco (ST) is increasing. Many ST users wish to quit but lack resources. There is a need for innovative, validated, and widely applicable low-cost interventions to facilitate ST cessation. An effective interactive Internet-based cessation program could meet this need. This proposed study will compare the efficacy of a tailored Internet-based interactive ST cessation program with a Web site that provides typical cessation materials and links to other Web-based ST resources. Smokeless tobacco users who wish to quit will be recruited to our Web site and randomized to receive either the personalized, interactive multimedia program plus links to other Web-based resources (Tailored Condition) or a cessation information site with links to other Web-based resources (Usual Care Condition). The Tailored Condition will be based on empirically validated ST cessation programs and will take advantage of the unique properties of the Internet to provide individualized cessation assistance, and social support via forums and chat rooms. After completion of entry criteria questions and informed consent, 2,400 ST users aged 18 and older will be equally randomized to either the Usual Care Condition or the Tailored intervention Condition. Cessation outcomes will be evaluated at 6 weeks, 6 months, and 12 months post-enrollment via Internet surveys. The primary outcomes are tobacco cessation at 6- and 12-month follow-up, with quit rates expected to be higher in subjects in the Tailored Condition. The study will also investigate baseline subject characteristics, program utilization, social support, and process variables as predictive of cessation outcomes. A cost analysis will determine the cost per quit and relative cost-effectiveness of the two conditions. The public health potential of the proposed Web-based application to promote smokeless tobacco cessation is great. The use of the Internet as a resource for health care information continues to grow. An empirical evaluation of this delivery system for smokeless tobacco cessation is warranted and timely.



Publications

Randomized Controlled Trial Of The Combined Effects Of Web And Quitline Interventions For Smokeless Tobacco Cessation
Authors: Danaher B.G. , Severson H.H. , Zhu S.H. , Andrews J.A. , Cummins S.E. , Lichtenstein E. , Tedeschi G.J. , Hudkins C. , Widdop C. , Crowley R. , et al. .
Source: Internet Interventions : The Application Of Information Technology In Mental And Behavioural Health, 2015-05-01 00:00:00.0; 2(2), p. 143-151.
PMID: 25914872
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A Comparison Of Three Smokeless Tobacco Dependence Measures
Authors: Ebbert J.O. , Severson H.H. , Danaher B.G. , Schroeder D.R. , Glover E.D. .
Source: Addictive Behaviors, 2012 Nov; 37(11), p. 1271-7.
PMID: 22762958
Related Citations

Modeling Missing Binary Outcome Data In A Successful Web-based Smokeless Tobacco Cessation Program
Authors: Smolkowski K. , Danaher B.G. , Seeley J.R. , Kosty D.B. , Severson H.H. .
Source: Addiction (abingdon, England), 2010 Jun; 105(6), p. 1005-15.
PMID: 20148782
Related Citations

Methodological Issues In Research On Web-based Behavioral Interventions
Authors: Danaher B.G. , Seeley J.R. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 2009 Aug; 38(1), p. 28-39.
PMID: 19806416
Related Citations

Mediators Of A Successful Web-based Smokeless Tobacco Cessation Program
Authors: Danaher B.G. , Smolkowski K. , Seeley J.R. , Severson H.H. .
Source: Addiction (abingdon, England), 2008 Oct; 103(10), p. 1706-12.
PMID: 18715238
Related Citations

Chewfree.com: Evaluation Of A Web-based Cessation Program For Smokeless Tobacco Users
Authors: Severson H.H. , Gordon J.S. , Danaher B.G. , Akers L. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2008 Feb; 10(2), p. 381-91.
PMID: 18236303
Related Citations

Use of smokeless tobacco is a risk factor for cigarette smoking.
Authors: Severson H.H. , Forrester K.K. , Biglan A. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2007 Dec; 9(12), p. 1331-7.
PMID: 18058351
Related Citations

Measuring participant rurality in Web-based interventions.
Authors: Danaher B.G. , Hart L.G. , McKay H.G. , Severson H.H. .
Source: Bmc Public Health, 2007-08-31 00:00:00.0; 7, p. 228.
EPub date: 2007-08-31 00:00:00.0.
PMID: 17764564
Related Citations

Self-help Cessation Programs For Smokeless Tobacco Users: Long-term Follow-up Of A Randomized Trial
Authors: Severson H.H. , Andrews J.A. , Lichtenstein E. , Danaher B.G. , Akers L. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2007 Feb; 9(2), p. 281-9.
PMID: 17365759
Related Citations

Successful Participant Recruitment Strategies For An Online Smokeless Tobacco Cessation Program
Authors: Gordon J.S. , Akers L. , Severson H.H. , Danaher B.G. , Boles S.M. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2006 Dec; 8 Suppl 1, p. S35-41.
PMID: 17491169
Related Citations

Tobacco Control Research: A Journey Of Discovery In Prevention And Cessation
Authors: Severson,H.H. .
Source: American Journal Of Health Behavior, 2006 Nov-Dec; 30(6), p. 567-79.
PMID: 17096614
Related Citations

Defining Participant Exposure Measures In Web-based Health Behavior Change Programs
Authors: Danaher B.G. , Boles S.M. , Akers L. , Gordon J.S. , Severson H.H. .
Source: Journal Of Medical Internet Research, 2006; 8(3), p. e15.
PMID: 16954125
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