Grant Number:	5R01CA078995-04 Interpret this number
Primary Investigator:	Carver, Charles
Organization:	University Of Miami Coral Gables
Project Title:	Quality of Life in Adult Cancer Survivors
Fiscal Year:	2001

DESCRIPTION: (Applicant's Description) This project will examine quality of life (QOL) in adult long-term survivors of cancer (five years or more cancer-free). Given what is seen as a lack of good measures, the project's first goal is to develop a measure of QOL for this group, based on extensive interviews of long-term cancer survivors and on sound principles of test construction. After development of this measure, the second goal will be to assess QOL in a tri-ethnic (Hispanic, non-Hispanic White, and African American) sample of survivors of breast, prostate, colorectal cancers, and Hodgkin's disease, yielding information on normative experiences of long-term survivors, on possible ethnic differences, and on long-term impact of adjuvant therapies. We will also examine this group prospectively, testing factors that may influence further change in their QOL over time. Indeed, studying how differences in personality, social context, coping patterns, etc. influence long-term QOL is the project's third goal, taking advantage of the fact that we have been studying psychosocial adaptation to breast cancer for many years. Women who participated in those earlier studies completed measures of several resilience and vulnerability factors at the time of their cancer diagnosis. Now, 5 to 13 years later, we will return to these women, assess QOL, and use the measures collected earlier to prospectively predict current QOL. We will be able to examine several personal and contextual variables as prospective predictors in this way. The fact that we have this information available on large numbers of women who were treated for breast cancer also permits us to conduct a very different kind of study of survivorship. In particular, we will be able to test these variables (collected early in the cancer experience) as predictors of who survives free from cancer at particular lengths of time after treatment. The idea that psychosocial variables play a role in recurrence (or its absence) is controversial. We will examine several psychosocial variables from our data sets that are relevant as predictors of recurrence. Conducting this research at this time will allow us to make use of - and further solidify - a resource that has been years in building. There is a large cadre of survivors of breast cancer about whom we know a good deal, thanks to their earlier research involvement. These people can continue providing important information about the experience of cancer survivorship and what qualities make the process easier or harder.




Self-regulation processes and health: the importance of optimism and goal adjustment.
Authors: Rasmussen H.N. , Wrosch C. , Scheier M.F. , Carver C.S. .
Source: Journal Of Personality, 2006 Dec; 74(6), p. 1721-47.
PMID: 17083664
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Evaluation of the Quality of Life in Adult Cancer Survivors (QLACS) scale for long-term cancer survivors in a sample of breast cancer survivors.
Authors: Avis N.E. , Ip E. , Foley K.L. .
Source: Health And Quality Of Life Outcomes, 2006-12-01 00:00:00.0; 4, p. 92.
EPub date: 2006-12-01 00:00:00.0.
PMID: 17140438
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Relations of serotonin function to personality: current views and a key methodological issue.
Authors: Carver C.S. , Miller C.J. .
Source: Psychiatry Research, 2006-09-30 00:00:00.0; 144(1), p. 1-15.
EPub date: 2006-09-30 00:00:00.0.
PMID: 16914207
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Quality of life among long-term survivors of breast cancer: Different types of antecedents predict different classes of outcomes.
Authors: Carver C.S. , Smith R.G. , Petronis V.M. , Antoni M.H. .
Source: Psycho-oncology, 2006 Sep; 15(9), p. 749-58.
PMID: 16304622
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A qualitative exploration of the cancer experience among long-term survivors: comparisons by cancer type, ethnicity, gender, and age.
Authors: Foley K.L. , Farmer D.F. , Petronis V.M. , Smith R.G. , McGraw S. , Smith K. , Carver C.S. , Avis N. .
Source: Psycho-oncology, 2006 Mar; 15(3), p. 248-58.
PMID: 15940742
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Extreme Goal Setting and Vulnerability to Mania Among Undiagnosed Young Adults.
Authors: Johnson S.L. , Carver C.S. .
Source: Cognitive Therapy And Research, 2006; 30(3), p. 377-395.
PMID: 20198117
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Enhancing adaptation during treatment and the role of individual differences.
Authors: Carver C.S. .
Source: Cancer, 2005-12-01 00:00:00.0; 104(11 Suppl), p. 2602-7.
PMID: 16247785
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Optimistic personality and psychosocial well-being during treatment predict psychosocial well-being among long-term survivors of breast cancer.
Authors: Carver C.S. , Smith R.G. , Antoni M.H. , Petronis V.M. , Weiss S. , Derhagopian R.P. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2005 Sep; 24(5), p. 508-16.
PMID: 16162045
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Assessing quality of life in adult cancer survivors (QLACS).
Authors: Avis N.E. , Smith K.W. , McGraw S. , Smith R.G. , Petronis V.M. , Carver C.S. .
Source: Quality Of Life Research : An International Journal Of Quality Of Life Aspects Of Treatment, Care And Rehabilitation, 2005 May; 14(4), p. 1007-23.
PMID: 16041897
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Perceived partner reactions to diagnosis and treatment of breast cancer: impact on psychosocial and psychosexual adjustment.
Authors: Wimberly S.R. , Carver C.S. , Laurenceau J.P. , Harris S.D. , Antoni M.H. .
Source: Journal Of Consulting And Clinical Psychology, 2005 Apr; 73(2), p. 300-11.
PMID: 15796638
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Impulse and constraint: perspectives from personality psychology, convergence with theory in other areas, and potential for integration.
Authors: Carver C.S. .
Source: Personality And Social Psychology Review : An Official Journal Of The Society For Personality And Social Psychology, Inc, 2005; 9(4), p. 312-33.
PMID: 16223354
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Finding benefit in breast cancer during the year after diagnosis predicts better adjustment 5 to 8 years after diagnosis.
Authors: Carver C.S. , Antoni M.H. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2004 Nov; 23(6), p. 595-8.
PMID: 15546227
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Negative affects deriving from the behavioral approach system.
Authors: Carver C.S. .
Source: Emotion (washington, D.c.), 2004 Mar; 4(1), p. 3-22.
PMID: 15053723
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Adaptive self-regulation of unattainable goals: goal disengagement, goal reengagement, and subjective well-being.
Authors: Wrosch C. , Scheier M.F. , Miller G.E. , Schulz R. , Carver C.S. .
Source: Personality & Social Psychology Bulletin, 2003 Dec; 29(12), p. 1494-508.
PMID: 15018681
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Dispositional pessimism predicts illness-related disruption of social and recreational activities among breast cancer patients.
Authors: Carver C.S. , Lehman J.M. , Antoni M.H. .
Source: Journal Of Personality And Social Psychology, 2003 Apr; 84(4), p. 813-21.
PMID: 12703650
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Coping and distress among women under treatment for early stage breast cancer: comparing African Americans, Hispanics and non-Hispanic Whites.
Authors: Culver J.L. , Arena P.L. , Antoni M.H. , Carver C.S. .
Source: Psycho-oncology, 2002 Nov-Dec; 11(6), p. 495-504.
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The role of optimism in social network development, coping, and psychological adjustment during a life transition.
Authors: Brissette I. , Scheier M.F. , Carver C.S. .
Source: Journal Of Personality And Social Psychology, 2002 Jan; 82(1), p. 102-11.
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On the continuous calibration of happiness.
Authors: Carver C.S. .
Source: American Journal Of Mental Retardation : Ajmr, 2000 Sep; 105(5), p. 336-41.
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Scaling back goals and recalibration of the affect system are processes in normal adaptive self-regulation: understanding 'response shift' phenomena.
Authors: Carver C.S. , Scheier M.F. .
Source: Social Science & Medicine (1982), 2000 Jun; 50(12), p. 1715-22.
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Influences of personality and coping variables on health behaviors and health outcomes.
Authors: Carver C.S. .
Source: Compendium Of Continuing Education In Dentistry. (jamesburg, N.j. : 1995). Supplement, 2000; (30), p. 49-56; quiz 66-7.
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