DESCRIPTION (provided by applicant): The First International Conference on
Male-Mediated Developmental Toxicity was held in Pittsburgh in 1992. This
Conference was the first to bring together clinicians, biologists and
epidemiologists from around the world to discuss various aspects of research
in the area of male-mediated effects on progeny. This was a highly successful
conference that resulted in a book with the proceedings. Since 1992, the field
has progressed significantly; leading organizers and participants of the first
conference to schedule a Second International Conference on Male-Mediated
Developmental Toxicity, to be held in Montreal, Quebec, Canada from June 20-
23, 2001. The goals of the Second International Meeting on Male-Mediated
Developmental Toxicity are to identify new developments and directions in the
field over the past decade, as well as the challenges for the years ahead, and
to promote communication/integration among basic scientists, epidemiologists
and clinicians. The scientific program will feature leaders in the fields of
reproductive toxicology, teratology, epidemiology, cancer, developmental
biology, environmental toxicology, and occupational health. The conference
will include state-of-the-art lectures, symposia, poster sessions and
workshops. Plenum Press has agreed to once again publish the meeting
proceedings. The most recent developments will be presented on a range of
topics including: parental legacies and genomics; lifestyle, occupational and
therapeutic paternal exposures and effects; effects on the gamete-packaging of
human sperm; effects on fertilization and the embryo; role of DNA repair and
germ cell apoptosis; stem cells, epigenetics and cloning; markers of sperm
quality and relationship to progeny; model systems; implications to clinicians
and genetic counsellors; and impact on reproductive technology and
legislation. It is anticipated that this conference will foster improvements
in risk assessment for male-mediated developmental effects and aid in the
identification of specific biomarkers of damage. The meeting is organized to
maximize participation and increase interactions among attendees and speakers
as well as senior and junior investigators and students. The first
International Conference received funding from NIH based on the high quality
of the program and the important contribution of the meeting to this
interdisciplinary area of research.
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