We propose to undertake cancer prevention studies that focus on both
tobacco use behavior and dietary behavior. We will rely heavily on our
already developed core expertise in telephone counselling and assessment
and in biostatistical analysis. Our studies of tobacco use behavior are
designed to further hasten the progress towards a smokefree society:
Project One seeks to develop and test an effective intervention for those
smokers who seek information on quitting but who are not ready to take the
decisive step to quit Project 2 seeks to extend to adolescents our previous
research in helping young adult smokers successfully quit. Project 3
extends our considerable work in using available data sets to understand
the natural history of smoking behavior and to develop hypotheses for
altering that behavior. In particular, this project will enable us to
further test intervention hypotheses developed in Projects 1 and 2. We are
interested in a role that diet may have in preventing or delaying secondary
cancer events in women who have survived breast cancer. Our hypothesis is
that a protective effect may occur from a dietary pattern that consists of
the frequent ingestion of a wide variety of nutrients that have weak
anticarcinogenic activity. Our goal is to undertake a randomized
controlled trial of this dietary pattern hypothesis. Project 4 will extend
our feasibility study demonstrating that we can achieve a significantly
different dietary pattern among an ethnically diverse population and
maintain that difference over time. We will look for early support for our
hypothesis from the cancer event pattern in our two random groups. Project
5 is an analytic project that explores the relationship between self-
reported dietary intakes and plasma carotenoid concentration in these
groups of women and seeks to inform decisions on dietary guidelines in
these cancer prevention studies.
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