||5R44CA069864-03 Interpret this number
||Software for Geographic Boundary Analysis
DESCRIPTION: (From the Investigator's Abstract) This Phase II SBIR
project will complete development of geographic boundary analysis software
for the evaluation of spatial relationships among oncogenes, the
environment, and cancer. Boundaries are the edges of homogeneous areas or
are zones of rapid change in a variable's value, and are of fundamental
scientific interest in fields such as population genetics, exposure
assessment, and cancer epidemiology. Examples include borders of health,
water, and political districts; features such as rivers and roads; edges
of pollution plumes; ecotones; and zones of rapid change in health
outcomes such as cancer mortality. During Phase I, investigators
developed prototype software (GEM) and User Manual. The prototype was
evaluated by a panel of experts and applied to detect zones of rapid
change in cancer mortality in Illinois. These results firmly demonstrate
project feasibility, and Phase II will build on them to accomplish five
objectives: 1) Refine the software in response to expert panel's
critique; 2) Conduct applied studies for inclusion in the User Manual; 3)
Assess the statistical power of boundary statistics; 4) Implement fuzzy
boundary statistics; and 5) Prepare educational materials for university
courses. Accomplishment of these aims will provide the educational
foundation and tools needed to explore boundary-generating phenomena.
PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE
Geographic boundaries in breast, lung and colorectal cancers in relation to exposure to air toxics in Long Island, New York.
, Greiling D.A.
International journal of health geographics, 2003-02-17; 2(1), p. 4.
The map comparison problem: tests for the overlap of geographic boundaries.
Statistics in medicine, 1995 Nov 15-30; 14(21-22), p. 2343-61.