This study will develop, test, and disseminate cancer prevention
strategies for high-risk youth, defined as adolescents aged 10 to 11
years from families with incomes that fall below the Federal poverty
line. The study has three aims: 1) Develop intervention strategies
suitable for community sites to reduce cancer risks associated with
tobacco and alcohol use; 2) Test the effects of these strategies in a
randomized clinical trial; and 3) Disseminate the tested prevention
The proposed study will occur in three phases. In a 12-month preparation
phase, the investigators will develop intervention and measurement
protocols, draw a representative sample of community organizations for
study participation, and recruit and train intervention delivery agents.
An 18-month implementation phase will initiate field operations of a
clinical trial, including pretesting, intervention delivery, process data
collection, and posttesting. A follow-up and dissemination phase in the
last 30 months of the study will involve booster session delivery, data
analyses, and, if outcome results are positive, intervention
The study's cancer risk reduction strategy includes skills intervention
that will engage groups of high-risk youth in community settings and
parent-enhanced skills intervention that will help family members nurture
and sustain youths' cancer risk reduction efforts. The randomized field
trial will involve the administration of psychometrically tested and
refined pretest measurement batteries to all consenting youths at all
collaborating community sites. Following analyses of pretest data to
ensure comparability among sites, sites will be divided among three arms:
a skills intervention alone arm, a parent-enhanced skills intervention
arm, and a no-intervention control arm. Initial delivery of skills and
parent-enhanced skills interventions will occur at intervention condition
After initial intervention and semiannually, all youths will retake
outcome measurement batteries and intervention arm youths will receive
booster sessions specific to the initial intervention that they received.
The planned research enjoys the support of community organizations in
greater New York City that serve high-risk youth.
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