Grant Details
Grant Number: |
5R03CA077118-02 Interpret this number |
Primary Investigator: |
Yang, Ping |
Organization: |
Mayo Clinic |
Project Title: |
Development of Lung Cancer Epidemiology Research |
Fiscal Year: |
1998 |
Abstract
DESCRIPTION (Applicant's Description) Lung cancer has been the leading cause
of death due to malignancy in the United States for decades. While
cigarette smoking has been identified as a major risk factor, it is known
that only a small proportion of all heavy smokers will develop lung cancer
eventually. Evidence of lung cancer familial aggregation suggests
variability in inherited susceptibility. Genetic polymorphisms in several
microsomal mixed-function oxidases and phase II detoxification enzymes, both
of which are important in the activation and detoxification of chemical
carcinogens, have been reported to affect risk of lung cancer. Genomic
alterations and instabilities have also been indicated for lung cancer risk
in the recent literature. In addition, studies of both smokers and
nonsmokers suggested overlapping etiology between lung cancer and selected
chronic pulmonary diseases. Thoroughly evaluating the intricate roles and
interactive effects of major susceptibility gene(s), risk modifier gene(s),
and exogenous carcinogens requires a comprehensive study design and data
resource which integrates the traditional epidemiologic approaches and newly
developed genetic and molecular tools. The purpose of this protocol is to
identify newly diagnosed lung cancer patients seen at Mayo Clinic and to
build a patient, family and biosample resource for a comprehensive
genetic-epidemiologic study of lung cancer. From the estimated 3,840 lung
cancer patients newly diagnosed at the clinic between 1/1/1995 and
12/31/1998, 1,118 will be identified as study subjects. There are 250
Olmsted county residents anticipated for population-based studies. Data on
approximately 900 selected clinical-based patients will be available for the
following genetic and molecular epidemiologic studies: (1) 384 patients
with positive family history of lung cancer and 152 patients with strong
family history of cancer in general will be ascertained for identifying lung
cancer susceptibility gene(s); (2) 190 nonsmoking and 114 young-age (50
years old at diagnosis) patients will be identified for investigating the
causes other than or in addition to tobacco smoking; (3) 100 sporadic cases
who are smokers older than 50 years will also be included as an internal
comparison group. Thus, the developed data resource will enable us to
further test and locate the lung cancer susceptibility gene and its
interaction with other genes and tobacco exposure. A specific hypothesis,
i.e. whether lung cancer is associated with alpha-1 antitrypsin deficiency
heterozygous status, will be tested in this proposed study.
Publications
Targeted therapy‑associated cardiotoxicity in patients with stage‑IV lung cancer with or without cardiac comorbidities.
Authors: Peng Y.
, Li D.
, Wampfler J.A.
, Luo Y.H.
, Kumar A.V.
, Gu Z.
, Kosuru N.
, Yu N.Y.
, Wang Z.
, Leventakos K.
, et al.
.
Source: Oncology Reports, 2025 Feb; 53(2), .
EPub date: 2024-12-20 00:00:00.0.
PMID: 39704259
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Dermatologic toxicity associated with targeted and immunotherapies in stage-IV non-small cell lung cancer patients: A 14-year cohort.
Authors: Peng Y.
, Kumar A.V.
, Gu Z.
, Kosuru N.
, Wampfler J.A.
, Reck Dos Santos P.A.
, Yu N.Y.
, D'Cunha J.
, Ernani V.
, Costello C.M.
, et al.
.
Source: Journal Of The American Academy Of Dermatology, 2024 Jul; 91(1), p. 172-175.
EPub date: 2024-03-29 00:00:00.0.
PMID: 38556092
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Extracting Systemic Anticancer Therapy and Response Information From Clinical Notes Following the RECIST Definition.
Authors: Zuo X.
, Kumar A.
, Shen S.
, Li J.
, Cong G.
, Jin E.
, Chen Q.
, Warner J.L.
, Yang P.
, Xu H.
.
Source: Jco Clinical Cancer Informatics, 2024 Jun; 8, p. e2300166.
PMID: 38885475
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Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.
Authors: Shi J.
, Shiraishi K.
, Choi J.
, Matsuo K.
, Chen T.Y.
, Dai J.
, Hung R.J.
, Chen K.
, Shu X.O.
, Kim Y.T.
, et al.
.
Source: Nature Communications, 2023-05-26 00:00:00.0; 14(1), p. 3043.
EPub date: 2023-05-26 00:00:00.0.
PMID: 37236969
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Real-world efficacy of osimertinib in previously EGFR-TKI treated NSCLC patients without identification of T790M mutation.
Authors: Luo Y.H.
, Liu H.
, Wampfler J.A.
, Tazelaar H.D.
, Li Y.
, Peikert T.
, Liu D.
, Leventakos K.
, Chen Y.M.
, Yang Y.
, et al.
.
Source: Journal Of Cancer Research And Clinical Oncology, 2022 Aug; 148(8), p. 2099-2114.
EPub date: 2021-08-26 00:00:00.0.
PMID: 34436667
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Genetic Variation and Recurrent Haplotypes on Chromosome 6q23-25 Risk Locus in Familial Lung Cancer.
Authors: Musolf A.M.
, Simpson C.L.
, Moiz B.A.
, Pikielny C.W.
, Middlebrooks C.D.
, Mandal D.
, de Andrade M.
, Cole M.D.
, Gaba C.
, Yang P.
, et al.
.
Source: Cancer Research, 2021-06-15 00:00:00.0; 81(12), p. 3162-3173.
EPub date: 2021-04-14 00:00:00.0.
PMID: 33853833
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Rare deleterious germline variants and risk of lung cancer.
Authors: Liu Y.
, Xia J.
, McKay J.
, Tsavachidis S.
, Xiao X.
, Spitz M.R.
, Cheng C.
, Byun J.
, Hong W.
, Li Y.
, et al.
.
Source: Npj Precision Oncology, 2021-02-16 00:00:00.0; 5(1), p. 12.
EPub date: 2021-02-16 00:00:00.0.
PMID: 33594163
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The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients.
Authors: Jiang M.
, Fares A.F.
, Shepshelovich D.
, Yang P.
, Christiani D.
, Zhang J.
, Shiraishi K.
, Ryan B.M.
, Chen C.
, Schwartz A.G.
, et al.
.
Source: Lung Cancer (amsterdam, Netherlands), 2021 02; 152, p. 58-65.
EPub date: 2020-12-04 00:00:00.0.
PMID: 33352384
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Precise diagnosis of three top cancers using dbGaP data.
Authors: Liu X.Q.
, Liu X.S.
, Rong J.Y.
, Gao F.
, Wu Y.D.
, Deng C.H.
, Jiang H.Y.
, Li X.F.
, Chen Y.Q.
, Zhao Z.G.
, et al.
.
Source: Scientific Reports, 2021-01-12 00:00:00.0; 11(1), p. 823.
EPub date: 2021-01-12 00:00:00.0.
PMID: 33436913
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Efficient and Accurate Extracting of Unstructured EHRs on Cancer Therapy Responses for the Development of RECIST Natural Language Processing Tools: Part I, the Corpus.
Authors: Li Y.
, Luo Y.H.
, Wampfler J.A.
, Rubinstein S.M.
, Tiryaki F.
, Ashok K.
, Warner J.L.
, Xu H.
, Yang P.
.
Source: Jco Clinical Cancer Informatics, 2020 May; 4, p. 383-391.
PMID: 32364754
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Whole Exome Sequencing of Highly Aggregated Lung Cancer Families Reveals Linked Loci for Increased Cancer Risk on Chromosomes 12q, 7p, and 4q.
Authors: Musolf A.M.
, Moiz B.A.
, Sun H.
, Pikielny C.W.
, Bossé Y.
, Mandal D.
, de Andrade M.
, Gaba C.
, Yang P.
, Li Y.
, et al.
.
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2020 Feb; 29(2), p. 434-442.
EPub date: 2019-12-11 00:00:00.0.
PMID: 31826912
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5-year overall survival in patients with lung cancer eligible or ineligible for screening according to US Preventive Services Task Force criteria: a prospective, observational cohort study.
Authors: Luo Y.H.
, Luo L.
, Wampfler J.A.
, Wang Y.
, Liu D.
, Chen Y.M.
, Adjei A.A.
, Midthun D.E.
, Yang P.
.
Source: The Lancet. Oncology, 2019 Aug; 20(8), p. 1098-1108.
EPub date: 2019-06-26 00:00:00.0.
PMID: 31255490
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Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer.
Authors: Liu Y.
, Lusk C.M.
, Cho M.H.
, Silverman E.K.
, Qiao D.
, Zhang R.
, Scheurer M.E.
, Kheradmand F.
, Wheeler D.A.
, Tsavachidis S.
, et al.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2018 Oct; 13(10), p. 1483-1495.
EPub date: 2018-07-04 00:00:00.0.
PMID: 29981437
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Nomogram prediction of overall survival for patients with non-small-cell lung cancer incorporating pretreatment peripheral blood markers.
Authors: Xie D.
, Allen M.S.
, Marks R.
, Jiang G.
, Sun Z.
, Nichols F.
, Zhang M.
, Chen C.
, Aubry M.C.
, Jatoi A.
, et al.
.
Source: European Journal Of Cardio-thoracic Surgery : Official Journal Of The European Association For Cardio-thoracic Surgery, 2018-06-01 00:00:00.0; 53(6), p. 1214-1222.
PMID: 29293957
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Common TDP1 Polymorphisms in Relation to Survival among Small Cell Lung Cancer Patients: A Multicenter Study from the International Lung Cancer Consortium.
Authors: Lohavanichbutr P.
, Sakoda L.C.
, Amos C.I.
, Arnold S.M.
, Christiani D.C.
, Davies M.P.A.
, Field J.K.
, Haura E.B.
, Hung R.J.
, Kohno T.
, et al.
.
Source: Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research, 2017-12-15 00:00:00.0; 23(24), p. 7550-7557.
EPub date: 2017-10-03 00:00:00.0.
PMID: 28974547
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T category of non-small cell lung cancer invading the fissure to the adjacent lobe.
Authors: Liu M.
, Wigle D.
, Wampfler J.A.
, Dai J.
, Stoddard S.M.
, Xue Z.
, Nichols F.C.
, Jiang G.
, Yang P.
.
Source: The Journal Of Thoracic And Cardiovascular Surgery, 2017 Nov; 154(5), p. 1777-1783.e3.
EPub date: 2017-08-17 00:00:00.0.
PMID: 29042049
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Emotional Problems, Quality of Life, and Symptom Burden in Patients With Lung Cancer.
Authors: Morrison E.J.
, Novotny P.J.
, Sloan J.A.
, Yang P.
, Patten C.A.
, Ruddy K.J.
, Clark M.M.
.
Source: Clinical Lung Cancer, 2017 09; 18(5), p. 497-503.
EPub date: 2017-03-02 00:00:00.0.
PMID: 28412094
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Regional Emphysema Score Predicting Overall Survival, Quality Of Life And Pulmonary Function Recovery In Early-stage Lung Cancer Patients
Authors: Dai J.
, Liu M.
, Swensen S.J.
, Stoddard S.M.
, Wampfler J.A.
, Limper A.H.
, Jiang G.
, Yang P.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2017-01-23 00:00:00.0; , .
PMID: 28126539
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Nonsyndromic Cleft Lip With Or Without Cleft Palate And Cancer: Evaluation Of A Possible Common Genetic Background Through The Analysis Of Gwas Data
Authors: Dunkhase E.
, Ludwig K.U.
, Knapp M.
, Skibola C.F.
, Figueiredo J.C.
, Hosking F.J.
, Ellinghaus E.
, Landi M.T.
, Ma H.
, Nakagawa H.
, et al.
.
Source: Genomics Data, 2016 Dec; 10, p. 22-9.
PMID: 27630819
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Predictors Of Active Cancer Thromboembolic Outcomes: Validation Of The Khorana Score Among Patients With Lung Cancer
Authors: Mansfield A.S.
, Tafur A.J.
, Wang C.E.
, Kourelis T.V.
, Wysokinska E.M.
, Yang P.
.
Source: Journal Of Thrombosis And Haemostasis : Jth, 2016 Sep; 14(9), p. 1773-8.
PMID: 27273134
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Receptivity And Preferences For Lifestyle Programs To Reduce Cancer Risk Among Lung Cancer Family Members
Authors: Howell L.A.
, Brockman T.A.
, Sinicrope P.S.
, Patten C.A.
, Decker P.A.
, Busta A.
, Stoddard S.
, McNallan S.R.
, Yang P.
.
Source: Advances In Cancer Prevention, 2016 Sep; 1(3), .
PMID: 27917414
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Metformin Use And Young Age Lung Cancer: A Case Series Report
Authors: Deng B.O.
, Wang Y.I.
, Xie D.
, Stoddard S.M.
, Yang P.
.
Source: Oncology Letters, 2016 Apr; 11(4), p. 2899-2902.
PMID: 27073573
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Trends In Subpopulations At High Risk For Lung Cancer
Authors: Yang P.
, Wang Y.
, Wampfler J.A.
, Xie D.
, Stoddard S.M.
, She J.
, Midthun D.E.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2016 Feb; 11(2), p. 194-202.
PMID: 26811226
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Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer.
Authors: Liu Y.
, Kheradmand F.
, Davis C.F.
, Scheurer M.E.
, Wheeler D.
, Tsavachidis S.
, Armstrong G.
, Simpson C.
, Mandal D.
, Kupert E.
, et al.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2016 Jan; 11(1), p. 52-61.
PMID: 26762739
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Impact Of Self-reported Physical Activity And Health Promotion Behaviors On Lung Cancer Survivorship
Authors: Sloan J.A.
, Cheville A.L.
, Liu H.
, Novotny P.J.
, Wampfler J.A.
, Garces Y.I.
, Clark M.M.
, Yang P.
.
Source: Health And Quality Of Life Outcomes, 2016; 14, p. 66.
PMID: 27129406
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Secondhand Tobacco Smoke Exposure And Lung Adenocarcinoma In Situ/minimally Invasive Adenocarcinoma (ais/mia)
Authors: Kim C.H.
, Lee Y.C.
, Hung R.J.
, Boffetta P.
, Xie D.
, Wampfler J.A.
, Cote M.L.
, Chang S.C.
, Ugolini D.
, Neri M.
, et al.
.
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2015 Dec; 24(12), p. 1902-6.
PMID: 26503035
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Nomograms Predict Overall Survival For Patients With Small-cell Lung Cancer Incorporating Pretreatment Peripheral Blood Markers
Authors: Xie D.
, Marks R.
, Zhang M.
, Jiang G.
, Jatoi A.
, Garces Y.I.
, Mansfield A.
, Molina J.
, Yang P.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2015 Aug; 10(8), p. 1213-20.
PMID: 26200277
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Bilobectomy Versus Lobectomy For Non-small Cell Lung Cancer: A Comparative Study Of Outcomes, Long-term Survival, And Quality Of Life
Authors: Xie D.
, Deschamps C.
, Shen R.K.
, Deng B.
, Wampfler J.A.
, Cassivi S.D.
, Nichols F.C.
, Allen M.S.
, Wigle D.A.
, Yang P.
.
Source: The Annals Of Thoracic Surgery, 2015 Jul; 100(1), p. 242-50.
PMID: 26007206
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Dna Methylation And Rna Expression Profiles In Lung Adenocarcinomas Of Never-smokers
Authors: Mansfield A.S.
, Wang L.
, Cunningham J.M.
, Jen J.
, Kolbert C.P.
, Sun Z.
, Yang P.
.
Source: Cancer Genetics, 2015 May; 208(5), p. 253-60.
PMID: 25650174
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Trends In The Proportion Of Patients With Lung Cancer Meeting Screening Criteria
Authors: Wang Y.
, Midthun D.E.
, Wampfler J.A.
, Deng B.
, Stoddard S.M.
, Zhang S.
, Yang P.
.
Source: Jama, 2015-02-24 00:00:00.0; 313(8), p. 853-5.
PMID: 25710663
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Exposure To Secondhand Tobacco Smoke And Lung Cancer By Histological Type: A Pooled Analysis Of The International Lung Cancer Consortium (ilcco)
Authors: Kim C.H.
, Lee Y.C.
, Hung R.J.
, McNallan S.R.
, Cote M.L.
, Lim W.Y.
, Chang S.C.
, Kim J.H.
, Ugolini D.
, Chen Y.
, et al.
.
Source: International Journal Of Cancer, 2014-10-15 00:00:00.0; 135(8), p. 1918-30.
PMID: 24615328
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Clinical Outcomes And Changes In Lung Function After Segmentectomy Versus Lobectomy For Lung Cancer Cases
Authors: Deng B.
, Cassivi S.D.
, de Andrade M.
, Nichols F.C.
, Trastek V.F.
, Wang Y.
, Wampfler J.A.
, Stoddard S.M.
, Wigle D.A.
, Shen R.K.
, et al.
.
Source: The Journal Of Thoracic And Cardiovascular Surgery, 2014 Oct; 148(4), p. 1186-1192.e3.
PMID: 24746994
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Genome-wide Association Study Of Genetic Predictors Of Overall Survival For Non-small Cell Lung Cancer In Never Smokers
Authors: Wu X.
, Wang L.
, Ye Y.
, Aakre J.A.
, Pu X.
, Chang G.C.
, Yang P.C.
, Roth J.A.
, Marks R.S.
, Lippman S.M.
, et al.
.
Source: Cancer Research, 2013-07-01 00:00:00.0; 73(13), p. 4028-38.
PMID: 23704207
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Network-based Approach Identified Cell Cycle Genes As Predictor Of Overall Survival In Lung Adenocarcinoma Patients
Authors: Li Y.
, Tang H.
, Sun Z.
, Bungum A.O.
, Edell E.S.
, Lingle W.L.
, Stoddard S.M.
, Zhang M.
, Jen J.
, Yang P.
, et al.
.
Source: Lung Cancer (amsterdam, Netherlands), 2013 Apr; 80(1), p. 91-8.
PMID: 23357462
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Soluble Human Epidermal Growth Factor Receptor 2 (sher2) As A Potential Risk Assessment, Screening, And Diagnostic Biomarker Of Lung Adenocarcinoma
Authors: Cosentino-Boehm A.L.
, Lafky J.M.
, Greenwood T.M.
, Kimbler K.D.
, Buenafe M.C.
, Wang Y.
, Branscum A.J.
, Yang P.
, Maihle N.J.
, Baron A.T.
.
Source: Diagnostics (basel, Switzerland), 2013-01-14 00:00:00.0; 3(1), p. 13-32.
PMID: 26835666
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Increased Mir-708 Expression In Nsclc And Its Association With Poor Survival In Lung Adenocarcinoma From Never Smokers
Authors: Jang J.S.
, Jeon H.S.
, Sun Z.
, Aubry M.C.
, Tang H.
, Park C.H.
, Rakhshan F.
, Schultz D.A.
, Kolbert C.P.
, Lupu R.
, et al.
.
Source: Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research, 2012-07-01 00:00:00.0; 18(13), p. 3658-67.
PMID: 22573352
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Egfr Somatic Mutations In Lung Tumors: Radon Exposure And Passive Smoking In Former- And Never-smoking U.s. Women
Authors: Taga,M.
, Mechanic,L.E.
, Hagiwara,N.
, Vähäkangas,K.H.
, Bennett,W.P.
, Alavanja,M.C.
, Welsh,J.A.
, Khan,M.A.
, Lee,A.
, Diasio,R.
, et al.
.
Source: Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology, 2012 Jun; 21(6), p. 988-92.
PMID: 22523180
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Genetic Variations And Patient-reported Quality Of Life Among Patients With Lung Cancer
Authors: Sloan J.A.
, de Andrade M.
, Decker P.
, Wampfler J.
, Oswold C.
, Clark M.
, Yang P.
.
Source: Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology, 2012-05-10 00:00:00.0; 30(14), p. 1699-704.
PMID: 22454423
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Relationship Between Deficits In Overall Quality Of Life And Non-small-cell Lung Cancer Survival
Authors: Sloan J.A.
, Zhao X.
, Novotny P.J.
, Wampfler J.
, Garces Y.
, Clark M.M.
, Yang P.
.
Source: Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology, 2012-05-01 00:00:00.0; 30(13), p. 1498-504.
PMID: 22454418
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Genetic Variants Associated With The Risk Of Chronic Obstructive Pulmonary Disease With And Without Lung Cancer
Authors: de Andrade M.
, Li Y.
, Marks R.S.
, Deschamps C.
, Scanlon P.D.
, Olswold C.L.
, Jiang R.
, Swensen S.J.
, Sun Z.
, Cunningham J.M.
, et al.
.
Source: Cancer Prevention Research (philadelphia, Pa.), 2012 Mar; 5(3), p. 365-73.
PMID: 22044695
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Asthma And Lung Cancer Risk: A Systematic Investigation By The International Lung Cancer Consortium
Authors: Rosenberger A.
, Bickeböller H.
, McCormack V.
, Brenner D.R.
, Duell E.J.
, Tjønneland A.
, Friis S.
, Muscat J.E.
, Yang P.
, Wichmann H.E.
, et al.
.
Source: Carcinogenesis, 2012 Mar; 33(3), p. 587-97.
PMID: 22198214
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Quality Of Life And Symptom Burden Among Long-term Lung Cancer Survivors
Authors: Yang P.
, Cheville A.L.
, Wampfler J.A.
, Garces Y.I.
, Jatoi A.
, Clark M.M.
, Cassivi S.D.
, Midthun D.E.
, Marks R.S.
, Aubry M.C.
, et al.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2012 Jan; 7(1), p. 64-70.
PMID: 22134070
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Systematic Evaluation Of Genetic Variants In Three Biological Pathways On Patient Survival In Low-stage Non-small Cell Lung Cancer
Authors: Pankratz V.S.
, Sun Z.
, Aakre J.
, Li Y.
, Johnson C.
, Garces Y.I.
, Aubry M.C.
, Molina J.R.
, Wigle D.A.
, Yang P.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2011 Sep; 6(9), p. 1488-95.
PMID: 21792076
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Tobacco Smoking As A Risk Factor Of Bronchioloalveolar Carcinoma Of The Lung: Pooled Analysis Of Seven Case-control Studies In The International Lung Cancer Consortium (ilcco)
Authors: Boffetta P.
, Jayaprakash V.
, Yang P.
, Asomaning K.
, Muscat J.E.
, Schwartz A.G.
, Zhang Z.F.
, Le Marchand L.
, Cote M.L.
, Stoddard S.M.
, et al.
.
Source: Cancer Causes & Control : Ccc, 2011 Jan; 22(1), p. 73-9.
PMID: 21072579
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Gpc5 Gene And Its Related Pathways In Lung Cancer
Authors: Li Y.
, Yang P.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2011 Jan; 6(1), p. 2-5.
PMID: 21178712
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Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutation And Lung Cancer Risk
Authors: Li Y.
, Sun Z.
, Wu Y.
, Babovic-Vuksanovic D.
, Li Y.
, Cunningham J.M.
, Pankratz V.S.
, Yang P.
.
Source: Lung Cancer (amsterdam, Netherlands), 2010 Oct; 70(1), p. 14-21.
PMID: 20116881
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Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.
Authors: Truong T.
, Hung R.J.
, Amos C.I.
, Wu X.
, Bickeböller H.
, Rosenberger A.
, Sauter W.
, Illig T.
, Wichmann H.E.
, Risch A.
, et al.
.
Source: Journal Of The National Cancer Institute, 2010-07-07 00:00:00.0; 102(13), p. 959-71.
EPub date: 2010-07-07 00:00:00.0.
PMID: 20548021
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Methylation Markers For Small Cell Lung Cancer In Peripheral Blood Leukocyte Dna
Authors: Wang L.
, Aakre J.A.
, Jiang R.
, Marks R.S.
, Wu Y.
, Chen J.
, Thibodeau S.N.
, Pankratz V.S.
, Yang P.
.
Source: Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer, 2010 Jun; 5(6), p. 778-85.
PMID: 20421821
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