Grant Number:	5R01CA060586-03 Interpret this number
Primary Investigator:	Severson, Herbert
Organization:	Oregon Research Institute
Project Title:	Evaluation of Self Help Smokeeless Tobacco Cessation
Fiscal Year:	1998

DESCRIPTION: This study evaluates the effectiveness of an assisted self-help intervention for smokeless tobacco (SLT) cessation. The primary aim is to evaluate sustained (6-week and 12-month) cessation effects of the intervention. Secondary aims include assessment of the spontaneous quit rate by conducting a random-digit-dialed telephone survey of SLT users in Oregon, Washington, and Idaho; comparison of intervention quit rates with estimates from the telephone survey; assessment of the relationship between baseline demographic and psychosocial variables and SLT cessation and maintenance; economic analysis to determine relative cost-effectiveness, assessment of the impact of other tobacco use on SLT cessation, and process evaluation of intervention components. Subjects will be recruited from three Northwest states, and adults who express an interest in quitting their use of SLT will be screened by telephone for eligibility. Eligible subjects (estimated N 1,026) will be randomized to receive either (1) a self-help manual only (control), or (2) a self-help manual, a video tape on quitting, and two supportive phone calls (Assisted Self-Help condition). In Phase One of the study, the intervention and assessment will be developed and piloted. Phase Two will involve subject recruitment, randomization of subjects to the two conditions, and intervention and assessment. Phase Two also includes a random-digit-dialed telephone survey to interview 1,100 SLT users about current use, quit attempts, and interest in quitting. Phase Three involves one-year follow-up with all intervention subjects and with phone survey participants who were SLT users at baseline. Phase Four involves analysis of results, preparation of manuscripts, and revision of materials for dissemination. Data from this study can significantly contribute to our understanding of how to provide effective, low-intensity programs to help adults quit their use of snuff or chewing tobacco.




Women Helping Chewers: Effects Of Partner Support On 12-month Tobacco Abstinence In A Smokeless Tobacco Cessation Trial
Authors: Danaher B.G. , Lichtenstein E. , Andrews J.A. , Severson H.H. , Akers L. , Barckley M. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2009 Mar; 11(3), p. 332-5.
PMID: 19264861
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Cost-effectiveness Of Self-help Smokeless Tobacco Cessation Programs
Authors: Akers L. , Severson H.H. , Andrews J.A. , Lichtenstein E. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2007 Sep; 9(9), p. 907-14.
PMID: 17763106
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Self-help Cessation Programs For Smokeless Tobacco Users: Long-term Follow-up Of A Randomized Trial
Authors: Severson H.H. , Andrews J.A. , Lichtenstein E. , Danaher B.G. , Akers L. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2007 Feb; 9(2), p. 281-9.
PMID: 17365759
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Women Helping Chewers: Partner Support And Smokeless Tobacco Cessation
Authors: Lichtenstein E. , Andrews J.A. , Barckley M. , Akers L. , Severson H.H. .
Source: Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association, 2002 May; 21(3), p. 273-8.
PMID: 12027033
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From rapid smoking to the Internet: five decades of cessation research.
Authors: Lichtenstein E. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2002 May; 4(2), p. 139-45.
PMID: 12028845
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Who Enrolls In A Self-help Cessation Program For Smokeless Tobacco?
Authors: Andrews J.A. , Severson H.H. , Akers L. , Lichtenstein E. , Barckley M. .
Source: Addictive Behaviors, 2001 Sep-Oct; 26(5), p. 757-64.
PMID: 11676385
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A self-help cessation program for smokeless tobacco users: comparison of two interventions.
Authors: Severson H.H. , Andrews J.A. , Lichtenstein E. , Gordon J.S. , Barckley M. , Akers L. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2000 Nov; 2(4), p. 363-70.
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Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress.
Authors: Yamane Y. , Furuichi M. , Song R. , Van N.T. , Mulcahy R.T. , Ishikawa T. , Kuo M.T. .
Source: The Journal Of Biological Chemistry, 1998-11-20 00:00:00.0; 273(47), p. 31075-85.
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