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Grant Details

Grant Number: 5R01CA063146-05 Interpret this number
Primary Investigator: Urban, Nicole
Organization: Fred Hutchinson Cancer Research Center
Project Title: Mammography Tumor Registry for Breast Cancer Research
Fiscal Year: 1998


Abstract

Continued expansion and enhancement of the Mammography Tumor Registry (MTR) in Washington State is proposed in order to build a foundation for collaborative interdisciplinary research on mammography performance in a community setting. New methods for measuring the performance of mammography will be developed which will rely only on the dates of diagnosis and mammograms and characteristics of the tumor, in order to obviate the use of mammographers' coding of the reason for the mammogram, symptoms, assessment, or recommendations for follow up. The methods will be evaluated by analyzing variation in performance among facilities using new and standard methods as well as by using a simulation model to generate a gold standard. Using these measures, the roles of tumor biology, breast density, and hormone use in the failure of mammography will be investigated. The MTR will be expanded by adding 20 facilities selected for their potential contribution to research goals, and enhanced by adding a pathologist, surgeon, medical oncologist/cancer geneticist, and statistician to the investigator team. The database will be enhanced by including measurement of tumor biology (cell proliferation and genetic markers) in selected cases in which characteristics of the patient and mammograms are known. A pilot study is proposed to assess the feasibility of adding electronically transmitted pathology data directly to the MTR to allow timely feedback to mammography facilities to assist them in MQSA compliance. An ancillary study is proposed involving retrospective review of prior films ofrandontly selected cases diagnosed in TNM stage III or IV despite screening in the preceding 2-26 month period.



Publications

Computer-assisted Mammography Feedback Program (camfp) An Electronic Tool For Continuing Medical Education
Authors: Urban N. , Longton G.M. , Crowe A.D. , Drucker M.J. , Lehman C.D. , Peacock S. , Lowe K.A. , Zeliadt S.B. , Gaul M.A. .
Source: Academic Radiology, 2007 Sep; 14(9), p. 1036-42.
PMID: 17707310
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Mammography Surveillance Following Breast Cancer
Authors: Geller B.M. , Kerlikowske K. , Carney P.A. , Abraham L.A. , Yankaskas B.C. , Taplin S.H. , Ballard-Barbash R. , Dignan M.B. , Rosenberg R. , Urban N. , et al. .
Source: Breast Cancer Research And Treatment, 2003 Sep; 81(2), p. 107-15.
PMID: 14572153
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Concordance Of Breast Imaging Reporting And Data System Assessments And Management Recommendations In Screening Mammography
Authors: Taplin S.H. , Ichikawa L.E. , Kerlikowske K. , Ernster V.L. , Rosenberg R.D. , Yankaskas B.C. , Carney P.A. , Geller B.M. , Urban N. , Dignan M.B. , et al. .
Source: Radiology, 2002 Feb; 222(2), p. 529-35.
PMID: 11818624
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Use Of The American College Of Radiology Bi-rads To Report On The Mammographic Evaluation Of Women With Signs And Symptoms Of Breast Disease
Authors: Geller B.M. , Barlow W.E. , Ballard-Barbash R. , Ernster V.L. , Yankaskas B.C. , Sickles E.A. , Carney P.A. , Dignan M.B. , Rosenberg R.D. , Urban N. , et al. .
Source: Radiology, 2002 Feb; 222(2), p. 536-42.
PMID: 11818625
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Performance Of Screening Mammography Among Women With And Without A First-degree Relative With Breast Cancer
Authors: Kerlikowske K. , Carney P.A. , Geller B. , Mandelson M.T. , Taplin S.H. , Malvin K. , Ernster V. , Urban N. , Cutter G. , Rosenberg R. , et al. .
Source: Annals Of Internal Medicine, 2000-12-05 00:00:00.0; 133(11), p. 855-63.
PMID: 11103055
Related Citations

Effect Of Age And Breast Density On Screening Mammograms With False-positive Findings
Authors: Lehman C.D. , White E. , Peacock S. , Drucker M.J. , Urban N. .
Source: Ajr. American Journal Of Roentgenology, 1999 Dec; 173(6), p. 1651-5.
PMID: 10584815
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Instrumental Variables When Evaluating Screening Trials: Estimating The Benefit Of Detecting Cancer By Screening
Authors: McIntosh M.W. .
Source: Statistics In Medicine, 1999-10-30 00:00:00.0; 18(20), p. 2775-94.
PMID: 10521866
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On Estimating The Causal Effects Of Dnr Orders
Authors: McIntosh M.W. , Rubin D.B. .
Source: Medical Care, 1999 Aug; 37(8), p. 722-6.
PMID: 10448715
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Prostate-specific Antigen For Prostate Cancer Screening. Do Physician Characteristics Affect Its Use?
Authors: Edlefsen K.L. , Mandelson M.T. , McIntosh M.W. , Andersen M.R. , Wagner E.H. , Urban N. .
Source: American Journal Of Preventive Medicine, 1999 Jul; 17(1), p. 87-90.
PMID: 10429758
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Involvement In Decision-making And Breast Cancer Survivor Quality Of Life
Authors: Andersen M.R. , Urban N. .
Source: Annals Of Behavioral Medicine : A Publication Of The Society Of Behavioral Medicine, 1999 Summer; 21(3), p. 201-9.
PMID: 10626025
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Design Of A Study To Improve Accuracy In Reading Mammograms
Authors: Pepe M.S. , Urban N. , Rutter C. , Longton G. .
Source: Journal Of Clinical Epidemiology, 1997 Dec; 50(12), p. 1327-38.
PMID: 9449936
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Recent Trends In Breast Cancer Mortality Among White And Black Us Women
Authors: Chevarley F. , White E. .
Source: American Journal Of Public Health, 1997 May; 87(5), p. 775-81.
PMID: 9184505
Related Citations

Physician Gender And Screening: Do Patient Differences Account For Differences In Mammography Use?
Authors: Andersen M.R. , Urban N. .
Source: Women & Health, 1997; 26(1), p. 29-39.
PMID: 9311098
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