Grant Details
| Grant Number: |
1UG3CA315303-01 Interpret this number |
| Primary Investigator: |
Charlton, Mary |
| Organization: |
University Of Iowa |
| Project Title: |
Dissemination and Implementation of a Network-Based Facilitation Strategy to Improve Quality and Comprehensiveness of Cancer Care for Rural Patients |
| Fiscal Year: |
2026 |
Abstract
PROJECT SUMMARY
Rural cancer patients experience worse cancer survival outcomes than urban patients despite similar incidence
rates, due in part to significant barriers to accessing high-quality comprehensive care. Rural hospitals struggle
to offer guideline-concordant cancer care because of financial constraints, administrative burden, staffing
shortages, and physician recruitment and retention. One strategy to address this is through a network, whereby
a large cancer center serves as a hub for rural community hospitals and extends its resources to support them.
In our current R01 study, we successfully adapted an existing network model in Kentucky shown to improve
delivery of guideline-concordant care to create the Iowa Cancer Affiliation Network (I-CAN) with rural
hospitals in Iowa. Both networks use the Commission on Cancer (CoC) accreditation program as a framework
to enhance cancer care in its affiliate hospitals by providing support for achieving accreditation. The CoC
program employs evidence-based standards and disease-specific performance measures to ensure the
collection and monitoring of cancer care data, quality improvement, and delivery of comprehensive guideline-
concordant care. We identified the core functions of Kentucky’s intervention and iteratively developed a team-
based external facilitation strategy, Cancer Affiliated Networks Achieve Standards of Quality (CANASQ). This
approach was successfully used to enhance the capabilities of I-CAN affiliate hospitals to meet CoC standards,
including developing data infrastructure and offering the full range of cancer care services from psychosocial
services to palliative care. Based on our findings, the CoC has developed a modified accreditation track for rural
hospitals tailored to their limited resources. It is unknown whether the rural hospitals can implement the
modified accreditation standards independently. We hypothesize that external facilitation within a network
will continue to be necessary to successfully implement and maintain the quality standards of the rural
accreditation track because of limited capacity of under-resourced hospitals to integrate the multiple
components of accreditation without support. We aim to test our hypothesis with Kansas and Alabama, rural
states with existing cancer networks, by comparing CANASQ to a self-directed web-based toolkit. We will train
the networks in the CANASQ strategy and recruit 6 rural affiliate hospitals from each network to participate in
a pragmatic trial. Hospitals will be randomized to the CANASQ strategy vs. use of our self-directed web-based
toolkit. We will compare progress towards achieving the CoC standards of care and improvement in quality
measures between arms, and assess the feasibility, fidelity, acceptability, and sustainability of each strategy.
This work will fill in gaps in implementation research by increasing our understanding of the effectiveness of
external facilitation in rural settings. Widespread dissemination of the CANASQ strategy to other states could
result in reduced disparities in rural cancer outcomes and improved care.
Publications
None