Grant Number:	5R00CA281094-04 Interpret this number
Primary Investigator:	Lee, Donghee
Organization:	University Of Hawaii At Manoa
Project Title:	Identifying and Examining the Effects of Source and Presentation on Responses to Electronic Cigarette Public Education Messages in Young Adult Vapers and Non-Vapers
Fiscal Year:	2026

PROJECT SUMMARY E-cigarette use (vaping) in 18-24-year-olds is a public health crisis. It is an urgent public health priority to communicate to young adults about the health harm of vaping to stop and prevent them from vaping. However, effective communication has become challenging in the new age of health misinformation and low trust in health experts. My goal is to investigate the role of a trusted source and strategic message presentation to increase young adults’ acceptance of e- cigarette education messages to impact their behavior. In this two-phased study, I will determine an optimal source and message presentation type for young adult vapers and non-vapers, respectively (K99) and examine the effects of messages optimized for source and presentation on young adults’ vaping cessation and vaping prevention (R00). In phase 1 (K99), I will use a multi-method approach to examine two source (expert and peer) and two message presentation types (one-sided and two-sided) to identify the optimal message type for each vaping status population. First, I will use crowdsourcing testing to collect self-report measures on message acceptance, source trust, message reactance, and harm perceptions. Second, I will use psychophysiological testing to measure participants’ eye-tracking, heart rate, and skin conductance to assess their visual attention, orienting responses, and arousal during message exposure. I will produce a single dataset integrating the crowdsourced and psychophysiological data to determine the optimal source and presentation type for vapers and non-vapers. In phase 2 (R00), I will use a text messaging intervention in a randomized trial to examine the behavioral effects of messages optimized for source and presentation to one’s vaping status (vapers and non-vapers). Participants in each vaping status will be randomized to either the treatment (receiving e-cigarette education messages with a source and presentation type optimized to one’s vaping status) or control arm (receiving non-tobacco health messages) via text messaging over the course of 6 months. I will examine vaping cessation rates among vapers and vaping initiation rates among non-vapers. Results will inform the public health communication campaign development and may apply to other public education campaigns to reduce tobacco use in young people.




Tailoring e-cigarette health messages by vaping status: How source and message presentation type shape young adults' perceptions.
Authors: Lee D.N. , Villanti A.C. , Stevens E.M. .
Source: Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco, 2026-01-07 00:00:00.0; , .
EPub date: 2026-01-07 00:00:00.0.
PMID: 41499158
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Young Adults' Responses to E-Cigarette Advertisements: An Examination for Potential Regulation.
Authors: Stevens E.M. , Lee D.N. , Kim S. , Clayton R.B. , Oduguwa K. , Leshner G. , Mays D. , Villanti A.C. , Wagener T.L. .
Source: American Journal Of Preventive Medicine, 2025-11-13 00:00:00.0; 70(4), p. 108188.
EPub date: 2025-11-13 00:00:00.0.
PMID: 41241158
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Breaking the vape-stress cycle: communicating mental health risks of vaping to mitigate reactance.
Authors: Kim H.M. , Lee D.N. , Stevens H.R. , Stevens E.M. .
Source: Journal Of Public Health (oxford, England), 2025-11-03 00:00:00.0; , .
EPub date: 2025-11-03 00:00:00.0.
PMID: 41182294
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Young Adult Responses to Cannabis Prevention Message Features.
Authors: Liu J. , Lee D.N. , Stevens E.M. .
Source: Substance Use & Addiction Journal, 2025 Oct; 46(4), p. 829-836.
EPub date: 2025-04-04 00:00:00.0.
PMID: 40183250
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Public Engagement with Lung Cancer Screening Information: Topic Modeling of Lung Cancer-Related Reddit Posts.
Authors: Jaiswal A. , Amin S. , Amin S.M.S. , Lee D.N. , Park S.L. , Pokhrel P. .
Source: Current Oncology (toronto, Ont.), 2025-09-23 00:00:00.0; 32(10), .
EPub date: 2025-09-23 00:00:00.0.
PMID: 41149449
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Experiences With Cancer Screenings Among Arabic-Speaking Refugee Women.
Authors: Zaidi M. , Fantasia H.C. , Ahmed R. , Lee D.N. , Valdman O. , Poghosyan H. , Cooley M.E. , Lemon S.C. .
Source: Nursing For Women's Health, 2025 Apr; 29(2), p. 109-119.
EPub date: 2025-02-10 00:00:00.0.
PMID: 39947246
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How stress influences e-cigarette health message perceptions and intentions to abstain from vaping among young adults who vape.
Authors: Lee D.N. , Kim H.M. , Stevens E.M. .
Source: Addictive Behaviors, 2025 Jan; 160, p. 108174.
EPub date: 2024-09-23 00:00:00.0.
PMID: 39321718
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Association of Vaping Reasons with Stress, Anxiety, and Depression Among Young Adults Who Currently Vape.
Authors: Lee D.N. , Kim H.M. , Stevens E.M. .
Source: Substance Use & Misuse, 2025; 60(2), p. 188-194.
EPub date: 2024-10-31 00:00:00.0.
PMID: 39482818
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Motivations for Tobacco, Cannabis, and Their Co-Use Among U.S. Young Adults Who Engage in Same-Day Co-Use.
Authors: Liu J. , Lee D.N. , Stevens E.M. .
Source: Substance Use & Misuse, 2025; 60(4), p. 515-521.
EPub date: 2024-11-29 00:00:00.0.
PMID: 39612200
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