Grant Number:	4R37CA240807-06 Interpret this number
Primary Investigator:	Devine, Katie
Organization:	Rutgers Biomedical And Health Sciences
Project Title:	Bright Ideas-Young Adults: Problem-Solving Skills Training to Reduce Distress Among Young Adults with Cancer
Fiscal Year:	2025

Project Summary/Abstract Young adults with cancer experience more emotional distress and greater impairments in health-related quality of life (HRQOL) than older patients. Cancer diagnosis during young adulthood interferes with participation in normal developmental tasks such as obtaining higher education, starting a career, establishing financial independence, and developing romantic partnerships. This disruption in normal activities coupled with the unfamiliar and challenging demands of cancer treatment results in emotional distress and reduced HRQOL. There is an urgent and critical need to develop, test, and implement evidence-based interventions to support these young adults as they navigate perhaps the most challenging and debilitating period of their lives. Current psychosocial care does not adequately address the unique concerns of young adults. An optimal solution would give young adults the skills to deal with diverse and numerous stressors, address underdeveloped problem-solving ability characteristic of this age group, and be relatively simple to learn and use during the highly stressful time following a diagnosis of cancer. To address these clinical care gaps, the parent award is evaluating the efficacy of a problem-solving skills training intervention developed specifically for young adults and grounded in the core tenets of problem-solving therapy. “Bright IDEAS-Young Adults” (Bright IDEAS-YA) draws upon and notably extends prior research demonstrating the efficacy of a cognitive-behavioral problem-solving skills training program for reducing emotional distress in caregivers of pediatric patients. Bright IDEAS-YA is a 6-session, one- on-one intervention that teaches patients a systematic approach to overcome personal challenges across any life domain. It aims to enhance patients’ problem-solving ability in the face of significant stressors such as cancer. In preliminary work, young adults with cancer found Bright IDEAS-YA acceptable, relevant, and useful. Patients who received Bright IDEAS-YA showed improvements in problem-solving ability and reductions in symptoms of depression and anxiety. In the parent award, we are currently conducting a multi-site randomized controlled trial of Bright IDEAS-YA compared with enhanced usual psychosocial care with 344 YA patients (ages 18-39 years) undergoing cancer treatment. We will evaluate efficacy and examine mediators and moderators of intervention effects using assessments at baseline, post-intervention (3 months), and follow-up (6 and 12 months). In the proposed extension period, we will evaluate the sustainability of intervention effects by extending the follow-up to 2-years post-enrollment; identify barriers and facilitators of integrating Bright IDEAS-YA into clinical practice; and address barriers to access by culturally and linguistically translating for Hispanic young adults.




"There's a lot of unknowns": a thematic analysis of the experiences of young adults with cancer who died during a psychosocial intervention trial.
Authors: Bono M.H. , Reese S. , Levonyan-Radloff K. , Donovan K.A. , Sahler O.J.Z. , Barnett M.E. , Collins M. , Devine K.A. .
Source: Bmc Palliative Care, 2025-04-09 00:00:00.0; 24(1), p. 98.
EPub date: 2025-04-09 00:00:00.0.
PMID: 40205419
Related Citations

Protocol of a Multisite Randomized Controlled Trial of Bright IDEAS-Young Adults: Problem-Solving Skills Training to Reduce Distress among Young Adults with Cancer.
Authors: Devine K.A. , Ohman-Strickland P. , Barnett M. , Donovan K.A. , Thompson L.M.A. , Manne S.L. , Kearney J. , Levonyan-Radloff K. , Diaz D. , Dugad S. , et al. .
Source: Contemporary Clinical Trials, 2024 Oct; 145, p. 107656.
EPub date: 2024-08-05 00:00:00.0.
PMID: 39111386
Related Citations

Stop and Think: A Case Study Illustrating the Implementation of Bright IDEAS-YA Being Delivered via Telehealth to a Young Adult Cancer Patient.
Authors: Reese S. , Bono M.H. , Díaz D.B. , Donovan K.A. , Sahler O.J.Z. , Barnett M.E. , Levonyan-Radloff K. , Devine K.A. .
Source: Journal Of Clinical Psychology In Medical Settings, 2024-03-16 00:00:00.0; , .
EPub date: 2024-03-16 00:00:00.0.
PMID: 38491206
Related Citations

Factors Associated with COVID‑19 Vaccine Uptake Among Adolescents and Young Adults Recently Diagnosed with Cancer.
Authors: Kwok G. , Reese S. , Dugad S. , Donovan K.A. , Tsui J. , Sahler O.J.Z. , Levonyan-Radloff K. , Barnett M.E. , Manne S. , Ohman-Strickland P. , et al. .
Source: Journal Of Adolescent And Young Adult Oncology, 2022-11-11 00:00:00.0; , .
EPub date: 2022-11-11 00:00:00.0.
PMID: 36367717
Related Citations

Feasibility and Acceptability of Bright IDEAS-Young Adults: A Problem-Solving Skills Training Intervention.
Authors: Viola A.S. , Kwok G. , Levonyan-Radloff K. , Manne S.L. , Noll R.B. , Phipps S. , Sahler O.J.Z. , Devine K.A. .
Source: Cancers, 2022-06-25 00:00:00.0; 14(13), .
EPub date: 2022-06-25 00:00:00.0.
PMID: 35804896
Related Citations