Grant Number:	5R01CA033193-42 Interpret this number
Primary Investigator:	Schubauer-Berigan, Mary
Organization:	International Agency For Res On Cancer
Project Title:	Iarc Monographs on the Identification of Carcinogenic Hazards to Humans
Fiscal Year:	2024

Project Summary/Abstract Since 1971, the IARC Monographs on the Identification of Carcinogenic Hazards to Humans has provided an evidence-based approach to identifying the preventable causes of human cancer. Organizations worldwide rely on the IARC Monographs as a trustworthy source of carcinogenicity evaluations in their efforts to control cancer. Agents evaluated by the Monographs encompass chemicals, physical and biological agents, complex mixtures, occupational exposure circumstances, and other exposures of everyday life. To date, 1021 agents have been evaluated, with 121 classified as “carcinogenic”, 89 as “probably carcinogenic”, and 315 as “possibly carcinogenic” to humans. Agents are selected for evaluation based on evidence of human exposure and of carcinogenicity, and public health importance. Monographs are developed by independent global experts without conflicts of interest. Each Monograph includes systematic reviews of the pertinent scientific literature covering three unique streams of evidence (cancer in humans, cancer in experimental animals, and mechanistic evidence). The




Carcinogenicity of talc and acrylonitrile.
Authors: Stayner L.T. , Carreón-Valencia T. , Demers P.A. , Fritz J.M. , Sim M.R. , Stewart P. , Tsuda H. , Cardenas A. , Consonni D. , Davies L. , et al. .
Source: The Lancet. Oncology, 2024 Aug; 25(8), p. 962-963.
EPub date: 2024-07-05 00:00:00.0.
PMID: 38976996
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Advisory Group recommendations on priorities for the IARC Monographs.
Authors: Berrington de González A. , Masten S.A. , Bhatti P. , Fortner R.T. , Peters S. , Santonen T. , Yakubovskaya M.G. , Barouki R. , Barros S.B.M. , Barupal D. , et al. .
Source: The Lancet. Oncology, 2024 May; 25(5), p. 546-548.
EPub date: 2024-04-12 00:00:00.0.
PMID: 38621402
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Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid.
Authors: Zahm S. , Bonde J.P. , Chiu W.A. , Hoppin J. , Kanno J. , Abdallah M. , Blystone C.R. , Calkins M.M. , Dong G.H. , Dorman D.C. , et al. .
Source: The Lancet. Oncology, 2024 Jan; 25(1), p. 16-17.
EPub date: 2023-11-30 00:00:00.0.
PMID: 38043561
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Research Recommendations for Selected IARC-Classified Agents: Impact and Lessons Learned.
Authors: Turner M.C. , Cogliano V. , Guyton K. , Madia F. , Straif K. , Ward E.M. , Schubauer-Berigan M.K. .
Source: Environmental Health Perspectives, 2023 Oct; 131(10), p. 105001.
EPub date: 2023-10-30 00:00:00.0.
PMID: 37902675
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Carcinogenicity of aspartame, methyleugenol, and isoeugenol.
Authors: Riboli E. , Beland F.A. , Lachenmeier D.W. , Marques M.M. , Phillips D.H. , Schernhammer E. , Afghan A. , Assunção R. , Caderni G. , Corton J.C. , et al. .
Source: The Lancet. Oncology, 2023 Aug; 24(8), p. 848-850.
EPub date: 2023-07-13 00:00:00.0.
PMID: 37454664
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Firefighting and Cancer: A Meta-analysis of Cohort Studies in the Context of Cancer Hazard Identification.
Authors: DeBono N.L. , Daniels R.D. , Beane Freeman L.E. , Graber J.M. , Hansen J. , Teras L.R. , Driscoll T. , Kjaerheim K. , Demers P.A. , Glass D.C. , et al. .
Source: Safety And Health At Work, 2023 Jun; 14(2), p. 141-152.
EPub date: 2023-03-07 00:00:00.0.
PMID: 37389311
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Carcinogenicity of anthracene, 2-bromopropane, butyl methacrylate, and dimethyl hydrogen phosphite.
Authors: Cattley R.C. , Kromhout H. , Sun M. , Tokar E.J. , Abdallah M.A. , Bauer A.K. , Broadwater K.R. , Campo L. , Corsini E. , Houck K.A. , et al. .
Source: The Lancet. Oncology, 2023 May; 24(5), p. 431-432.
EPub date: 2023-03-23 00:00:00.0.
PMID: 36966774
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The carcinogenicity of opium consumption: a systematic review and meta-analysis.
Authors: M Filho A. , Turner M.C. , Warnakulasuriya S. , Richardson D.B. , Hosseini B. , Kamangar F. , Pourshams A. , Sewram V. , Cronin-Fenton D. , Etemadi A. , et al. .
Source: European Journal Of Epidemiology, 2023 Apr; 38(4), p. 373-389.
EPub date: 2023-02-11 00:00:00.0.
PMID: 36773182
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IARC-NCI workshop on an epidemiological toolkit to assess biases in human cancer studies for hazard identification: beyond the algorithm.
Authors: Schubauer-Berigan M.K. , Richardson D.B. , Fox M.P. , Fritschi L. , Guseva Canu I. , Pearce N. , Stayner L. , Berrington de Gonzalez A. .
Source: Occupational And Environmental Medicine, 2023 Mar; 80(3), p. 119-120.
EPub date: 2023-01-30 00:00:00.0.
PMID: 36717257
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Carcinogenicity of occupational exposure as a firefighter.
Authors: Demers P.A. , DeMarini D.M. , Fent K.W. , Glass D.C. , Hansen J. , Adetona O. , Andersen M.H. , Freeman L.E.B. , Caban-Martinez A.J. , Daniels R.D. , et al. .
Source: The Lancet. Oncology, 2022 Aug; 23(8), p. 985-986.
EPub date: 2022-07-01 00:00:00.0.
PMID: 35780778
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kc-hits: a tool to aid in the evaluation and classification of chemical carcinogens.
Authors: Reisfeld B. , de Conti A. , El Ghissassi F. , Benbrahim-Tallaa L. , Gwinn W. , Grosse Y. , Schubauer-Berigan M. .
Source: Bioinformatics (oxford, England), 2022-05-13 00:00:00.0; 38(10), p. 2961-2962.
PMID: 35561175
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Carcinogenicity of cobalt, antimony compounds, and weapons-grade tungsten alloy.
Authors: Karagas M.R. , Wang A. , Dorman D.C. , Hall A.L. , Pi J. , Sergi C.M. , Symanski E. , Ward E.M. , Arrandale V.H. , Azuma K. , et al. .
Source: The Lancet. Oncology, 2022 May; 23(5), p. 577-578.
EPub date: 2022-04-07 00:00:00.0.
PMID: 35397803
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Carcinogenicity of 1,1,1-trichloroethane and four other industrial chemicals.
Authors: IARC Monographs Vol 130 group .
Source: The Lancet. Oncology, 2021 Dec; 22(12), p. 1661-1662.
EPub date: 2021-11-11 00:00:00.0.
PMID: 34774220
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Prioritizing cancer hazard assessments for IARC Monographs using an integrated approach of database fusion and text mining.
Authors: Barupal D.K. , Schubauer-Berigan M.K. , Korenjak M. , Zavadil J. , Guyton K.Z. .
Source: Environment International, 2021 Nov; 156, p. 106624.
EPub date: 2021-05-10 00:00:00.0.
PMID: 33984576
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Carcinogenicity of gentian violet, leucogentian violet, malachite green, leucomalachite green, and CI Direct Blue 218.
Authors: IARC Monographs Vol 129 group .
Source: The Lancet. Oncology, 2021 May; 22(5), p. 585-586.
EPub date: 2021-03-25 00:00:00.0.
PMID: 33773614
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Carcinogenicity of some aromatic amines and related compounds.
Authors: IARC Monographs Vol 127 group .
Source: The Lancet. Oncology, 2020 Aug; 21(8), p. 1017-1018.
EPub date: 2020-06-25 00:00:00.0.
PMID: 32593317
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Carcinogenicity of some industrial chemical intermediates and solvents.
Authors: IARC Monographs Vol 125 group .
Source: The Lancet. Oncology, 2020 Jan; 21(1), p. 25-26.
EPub date: 2019-11-29 00:00:00.0.
PMID: 31787538
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Key Characteristics Approach to Carcinogenic Hazard Identification.
Authors: Guyton K.Z. , Rieswijk L. , Wang A. , Chiu W.A. , Smith M.T. .
Source: Chemical Research In Toxicology, 2018-12-17 00:00:00.0; 31(12), p. 1290-1292.
EPub date: 2018-12-06 00:00:00.0.
PMID: 30521319
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Software Tools to Facilitate Systematic Review Used for Cancer Hazard Identification.
Authors: Shapiro A.J. , Antoni S. , Guyton K.Z. , Lunn R.M. , Loomis D. , Rusyn I. , Jahnke G.D. , Schwingl P.J. , Mehta S.S. , Addington J. , et al. .
Source: Environmental Health Perspectives, 2018 Oct; 126(10), p. 104501.
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Re: 'Application of the key characteristics of carcinogens in cancer hazard evaluation': response to Goodman, Lynch and Rhomberg.
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Source: Carcinogenesis, 2018-07-30 00:00:00.0; 39(8), p. 1091-1093.
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Coffee Drinking and the Risk of Endometrial Cancer: An Updated Meta-Analysis of Observational Studies.
Authors: Lukic M. , Guha N. , Licaj I. , van den Brandt P.A. , Stayner L.T. , Tavani A. , Weiderpass E. .
Source: Nutrition And Cancer, 2018 May-Jun; 70(4), p. 513-528.
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Carcinogenicity of welding, molybdenum trioxide, and indium tin oxide.
Authors: Guha N. , Loomis D. , Guyton K.Z. , Grosse Y. , El Ghissassi F. , Bouvard V. , Benbrahim-Tallaa L. , Vilahur N. , Muller K. , Straif K. , et al. .
Source: The Lancet. Oncology, 2017 May; 18(5), p. 581-582.
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Prioritizing Chemicals for Risk Assessment Using Chemoinformatics: Examples from the IARC Monographs on Pesticides.
Authors: Guha N. , Guyton K.Z. , Loomis D. , Barupal D.K. .
Source: Environmental Health Perspectives, 2016 Dec; 124(12), p. 1823-1829.
EPub date: 2016-05-10 00:00:00.0.
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Carcinogenicity of pentachlorophenol and some related compounds.
Authors: Guyton K.Z. , Loomis D. , Grosse Y. , El Ghissassi F. , Bouvard V. , Benbrahim-Tallaa L. , Guha N. , Mattock H. , Straif K. , International Agency for Research on Cancer Monograph Working Group .
Source: The Lancet. Oncology, 2016 Dec; 17(12), p. 1637-1638.
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Target Organ Metabolism, Toxicity, and Mechanisms of Trichloroethylene and Perchloroethylene: Key Similarities, Differences, and Data Gaps.
Authors: Cichocki J.A. , Guyton K.Z. , Guha N. , Chiu W.A. , Rusyn I. , Lash L.H. .
Source: The Journal Of Pharmacology And Experimental Therapeutics, 2016 Oct; 359(1), p. 110-23.
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Carcinogenicity of drinking coffee, mate, and very hot beverages.
Authors: Loomis D. , Guyton K.Z. , Grosse Y. , Lauby-Secretan B. , El Ghissassi F. , Bouvard V. , Benbrahim-Tallaa L. , Guha N. , Mattock H. , Straif K. , et al. .
Source: The Lancet. Oncology, 2016 Jul; 17(7), p. 877-878.
EPub date: 2016-06-15 00:00:00.0.
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Carcinogenicity of some industrial chemicals.
Authors: Grosse Y. , Loomis D. , Guyton K.Z. , El Ghissassi F. , Bouvard V. , Benbrahim-Tallaa L. , Mattock H. , Straif K. , International Agency for Research on Cancer Monograph Working Group .
Source: The Lancet. Oncology, 2016 Apr; 17(4), p. 419-420.
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Polychlorinated Biphenyls and Polybrominated Biphenyls.

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